Literature DB >> 22246561

Genetic testing integration panels (GTIPs): a novel approach for considering integration of direct-to-consumer and other new genetic tests into patient care.

Wendy R Uhlmann1, Richard R Sharp.   

Abstract

There has been a dramatic increase in the number of genetic tests available but few tests have practice guidelines. In addition, many tests have become available outside of clinical settings through direct-to-consumer (DTC) companies and several offer tests not considered standard of care. To address several practical challenges associated with the rapid introduction of clinical and DTC genetic tests, we propose that genetic counselors and geneticists organize expert panels in their institutions to discuss the integration of new tests into patient care. We propose the establishment of Genetic Testing Integration Panels (GTIPs) to bring together local experts in medical genetics, genetic counseling, bioethics and law, health communication and clinical laboratory genetics. We describe key features of this approach and consider some of the potential advantages and limitations of using a GTIP to address the many clinical challenges raised by rapidly emerging clinical and DTC genetic tests.

Entities:  

Mesh:

Year:  2012        PMID: 22246561      PMCID: PMC4125014          DOI: 10.1007/s10897-011-9468-4

Source DB:  PubMed          Journal:  J Genet Couns        ISSN: 1059-7700            Impact factor:   2.537


  7 in total

1.  Bioethical and clinical dilemmas of direct-to-consumer personal genomic testing: the problem of misattributed equivalence.

Authors:  Charis Eng; Richard R Sharp
Journal:  Sci Transl Med       Date:  2010-02-03       Impact factor: 17.956

2.  Health-care referrals from direct-to-consumer genetic testing.

Authors:  Monica A Giovanni; Matthew R Fickie; Lisa S Lehmann; Robert C Green; Lisa M Meckley; David Veenstra; Michael F Murray
Journal:  Genet Test Mol Biomarkers       Date:  2010-10-28

3.  An agenda for personalized medicine.

Authors:  Pauline C Ng; Sarah S Murray; Samuel Levy; J Craig Venter
Journal:  Nature       Date:  2009-10-08       Impact factor: 49.962

4.  Primary care physicians' awareness, experience and opinions of direct-to-consumer genetic testing.

Authors:  Karen P Powell; Whitney A Cogswell; Carol A Christianson; Gaurav Dave; Amit Verma; Sonja Eubanks; Vincent C Henrich
Journal:  J Genet Couns       Date:  2011-07-16       Impact factor: 2.537

5.  Downsizing genomic medicine: approaching the ethical complexity of whole-genome sequencing by starting small.

Authors:  Richard R Sharp
Journal:  Genet Med       Date:  2011-03       Impact factor: 8.822

6.  Direct-to-consumer genetic testing: an assessment of genetic counselors' knowledge and beliefs.

Authors:  Kathryn T Hock; Kurt D Christensen; Beverly M Yashar; J Scott Roberts; Sarah E Gollust; Wendy R Uhlmann
Journal:  Genet Med       Date:  2011-04       Impact factor: 8.822

7.  The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group.

Authors:  Steven M Teutsch; Linda A Bradley; Glenn E Palomaki; James E Haddow; Margaret Piper; Ned Calonge; W David Dotson; Michael P Douglas; Alfred O Berg
Journal:  Genet Med       Date:  2009-01       Impact factor: 8.822

  7 in total
  6 in total

Review 1.  Ancestry Testing and the Practice of Genetic Counseling.

Authors:  Brianne E Kirkpatrick; Misha D Rashkin
Journal:  J Genet Couns       Date:  2016-10-04       Impact factor: 2.537

2.  The changing landscape of carrier screening: expanding technology and options?.

Authors:  Michelle L McGowan; Deborah Cho; Richard R Sharp
Journal:  Health Matrix Clevel       Date:  2013

3.  Utilization of Genetic Counseling after Direct-to-Consumer Genetic Testing: Findings from the Impact of Personal Genomics (PGen) Study.

Authors:  Diane R Koeller; Wendy R Uhlmann; Deanna Alexis Carere; Robert C Green; J Scott Roberts
Journal:  J Genet Couns       Date:  2017-05-16       Impact factor: 2.537

4.  Development of a Streamlined Work Flow for Handling Patients' Genetic Testing Insurance Authorizations.

Authors:  Wendy R Uhlmann; Katie Schwalm; Victoria M Raymond
Journal:  J Genet Couns       Date:  2017-04-24       Impact factor: 2.537

5.  Expanded carrier screening in reproductive healthcare: perspectives from genetics professionals.

Authors:  D Cho; M L McGowan; J Metcalfe; R R Sharp
Journal:  Hum Reprod       Date:  2013-04-14       Impact factor: 6.918

6.  Managing Expectational Language: Translational genetic professionals consider the clinical potential of next-generation sequencing technologies.

Authors:  Pei P Koay; Richard R Sharp
Journal:  New Genet Soc       Date:  2014-06-01
  6 in total

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