Literature DB >> 22195121

A pilot prospective feasibility study of organ-at-risk definition using Target Contour Testing/Instructional Computer Software (TaCTICS), a training and evaluation platform for radiotherapy target delineation.

Jayashree Kalpathy-Cramer1, Steven D Bedrick, Kelly Boccia, Clifton D Fuller.   

Abstract

Target volume delineation is a critical, but time-consuming step in the creation of radiation therapy plans used in the treatment of many types of cancer. However, variability in target volume definitions can introduce substantial differences in resulting doses to tumors and critical structures. We developed TaCTICS, a web-based educational training software application targeted towards non-expert users. We report on a small, prospective study to evaluate the utility of this online tool in improving conformance of regions-of-interest (ROIs) with a reference set. Eight residents contoured a set of structures for a head-and-neck cancer case. Subsequently, they were provided access to TaCTICS as well as contouring atlases to allow evaluation of their contours in reference to other users as well as reference ROIs. The residents then contoured a second case using these resources. Volume overlap metrics between the users showed a substantial improvement following the intervention. Additionally, 66% of users reported that they found TaCTICS to be a useful educational tool and all participants reported they would like to use TaCTICS to track their contouring skills over the course of their residency.

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Mesh:

Year:  2011        PMID: 22195121      PMCID: PMC3243186     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  22 in total

1.  CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines.

Authors:  Vincent Grégoire; Peter Levendag; Kian K Ang; Jacques Bernier; Marijel Braaksma; Volker Budach; Cliff Chao; Emmanuel Coche; Jay S Cooper; Guy Cosnard; Avraham Eisbruch; Samy El-Sayed; Bahman Emami; Cai Grau; Marc Hamoir; Nancy Lee; Philippe Maingon; Karin Muller; Hervé Reychler
Journal:  Radiother Oncol       Date:  2003-12       Impact factor: 6.280

Review 2.  Current ICRU definitions of volumes: limitations and future directions.

Authors:  James A Purdy
Journal:  Semin Radiat Oncol       Date:  2004-01       Impact factor: 5.934

Review 3.  The impact of gross tumor volume (GTV) and clinical target volume (CTV) definition on the total accuracy in radiotherapy theoretical aspects and practical experiences.

Authors:  Elisabeth Weiss; Clemens F Hess
Journal:  Strahlenther Onkol       Date:  2003-01       Impact factor: 3.621

4.  Contouring the middle and inner ear on radiotherapy planning scans.

Authors:  Heather D Pacholke; Robert J Amdur; Ilona M Schmalfuss; Debbie Louis; William M Mendenhall
Journal:  Am J Clin Oncol       Date:  2005-04       Impact factor: 2.339

Review 5.  IMRT: a review and preview.

Authors:  Thomas Bortfeld
Journal:  Phys Med Biol       Date:  2006-06-20       Impact factor: 3.609

Review 6.  Conformal radiotherapy: a clinical review.

Authors:  G Read
Journal:  Clin Oncol (R Coll Radiol)       Date:  1998       Impact factor: 4.126

Review 7.  Three-dimensional planning and conformal radiotherapy.

Authors:  C Harmer; M Bidmead
Journal:  Cancer Treat Res       Date:  1997

8.  Prospective randomized double-blind pilot study of site-specific consensus atlas implementation for rectal cancer target volume delineation in the cooperative group setting.

Authors:  Clifton D Fuller; Jasper Nijkamp; Joop C Duppen; Coen R N Rasch; Charles R Thomas; Samuel J Wang; Paul Okunieff; William E Jones; Daniel Baseman; Shilpen Patel; Carlo G N Demandante; Anna M Harris; Benjamin D Smith; Alan W Katz; Camille McGann; Jennifer L Harper; Daniel T Chang; Stephen Smalley; David T Marshall; Karyn A Goodman; Niko Papanikolaou; Lisa A Kachnic
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-04-18       Impact factor: 7.038

Review 9.  Target definition in prostate, head, and neck.

Authors:  Coen Rasch; Roel Steenbakkers; Marcel van Herk
Journal:  Semin Radiat Oncol       Date:  2005-07       Impact factor: 5.934

10.  Temporal changes in IMRT contouring of organs at risk for nasopharyngeal carcinoma - the learning curve blues and a tool that could help.

Authors:  Siddhartha Baxi; Eileen Park; Vincent Chong; Hans T Chung
Journal:  Technol Cancer Res Treat       Date:  2009-04
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  6 in total

1.  Development of a software for quantitative evaluation radiotherapy target and organ-at-risk segmentation comparison.

Authors:  Jayashree Kalpathy-Cramer; Musaddiq Awan; Steven Bedrick; Coen R N Rasch; David I Rosenthal; Clifton D Fuller
Journal:  J Digit Imaging       Date:  2014-02       Impact factor: 4.056

2.  Prospective assessment of an atlas-based intervention combined with real-time software feedback in contouring lymph node levels and organs-at-risk in the head and neck: Quantitative assessment of conformance to expert delineation.

Authors:  Musaddiq Awan; Jayashree Kalpathy-Cramer; G Brandon Gunn; Beth M Beadle; Adam S Garden; Jack Phan; Emma Holliday; William E Jones; Elizabeth Maani; Abhilasha Patel; Jehee Choi; Virginia Clyburn; Bundhit Tantiwongkosi; David I Rosenthal; Clifton D Fuller
Journal:  Pract Radiat Oncol       Date:  2012-12-21

3.  Auto-segmentation of the brachial plexus assessed with TaCTICS - a software platform for rapid multiple-metric quantitative evaluation of contours.

Authors:  Musaddiq Awan; Brandon Alan Dyer; Jayashree Kalpathy-Cramer; Eva Bongers; Max Dahele; Jinzhong Yang; Gary V Walker; Nikhil G Thaker; Emma Holliday; Andrew J Bishop; Charles R Thomas; David I Rosenthal; Clifton David Fuller
Journal:  Acta Oncol       Date:  2014-10-03       Impact factor: 4.089

4.  Quantitative assessment of target delineation variability for thymic cancers: Agreement evaluation of a prospective segmentation challenge.

Authors:  Emma Holliday; Clifton D Fuller; Jayashree Kalpathy-Cramer; Daniel Gomez; Andreas Rimner; Ying Li; Suresh Senan; Lynn D Wilson; Jehee Choi; Ritsuko Komaki; Charles R Thomas
Journal:  J Radiat Oncol       Date:  2015-11-03

5.  Consequences of anorectal cancer atlas implementation in the cooperative group setting: radiobiologic analysis of a prospective randomized in silico target delineation study.

Authors:  Panayiotis Mavroidis; Drosoula Giantsoudis; Musaddiq J Awan; Jasper Nijkamp; Coen R N Rasch; Joop C Duppen; Charles R Thomas; Paul Okunieff; William E Jones; Lisa A Kachnic; Niko Papanikolaou; Clifton D Fuller
Journal:  Radiother Oncol       Date:  2014-07-01       Impact factor: 6.280

6.  A Comparison of Lung Nodule Segmentation Algorithms: Methods and Results from a Multi-institutional Study.

Authors:  Jayashree Kalpathy-Cramer; Binsheng Zhao; Dmitry Goldgof; Yuhua Gu; Xingwei Wang; Hao Yang; Yongqiang Tan; Robert Gillies; Sandy Napel
Journal:  J Digit Imaging       Date:  2016-08       Impact factor: 4.056

  6 in total

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