BACKGROUND AND PURPOSE: Until now, endovascular treatment of symptomatic atherosclerotic stenosis in small intracranial arteries (≤2.5 mm) was limited. We evaluated the safety and efficacy of the treatment by using Wingspan stents in arteries of this caliber. MATERIALS AND METHODS: From March 2007 to July 2010, 53 symptomatic intracranial stenoses with narrowing of at least 50% in 53 patients were treated by using Wingspan stents. Clinical manifestations and imaging features were recorded. RESULTS: The technical success rate was 98.1%. There were no serious complications, with the exception of 1 patient who experienced a small cerebral hemorrhage caused by perforation of microwire. Thirty-nine patients (74%) were available for follow-up imaging with DSA. ISR was documented in 13 of these patients, including 2 patients with symptomatic ISR. The median length of the vascular lesions was 5.39 mm, and patients whose vascular lesions were longer than 5.39 mm had a much higher incidence of ISR than patients whose vascular lesions were shorter than 5.39 mm (53% versus 15%, respectively). The median ratio of the reference artery diameter to the stent diameter was 0.78, and patients whose ratio was smaller than 0.78 had a much higher incidence of ISR than patients whose ratio was larger than 0.78 (53% versus 15%, respectively). CONCLUSIONS: In our series, percutaneous transluminal angioplasty and stent placement of small intracranial arteries by using Wingspan stents was safe. The ISR rate was relatively high; most patients having ISR were asymptomatic. Further follow-up is needed to assess the long-term efficacy of this procedure.
BACKGROUND AND PURPOSE: Until now, endovascular treatment of symptomatic atherosclerotic stenosis in small intracranial arteries (≤2.5 mm) was limited. We evaluated the safety and efficacy of the treatment by using Wingspan stents in arteries of this caliber. MATERIALS AND METHODS: From March 2007 to July 2010, 53 symptomatic intracranial stenoses with narrowing of at least 50% in 53 patients were treated by using Wingspan stents. Clinical manifestations and imaging features were recorded. RESULTS: The technical success rate was 98.1%. There were no serious complications, with the exception of 1 patient who experienced a small cerebral hemorrhage caused by perforation of microwire. Thirty-nine patients (74%) were available for follow-up imaging with DSA. ISR was documented in 13 of these patients, including 2 patients with symptomatic ISR. The median length of the vascular lesions was 5.39 mm, and patients whose vascular lesions were longer than 5.39 mm had a much higher incidence of ISR than patients whose vascular lesions were shorter than 5.39 mm (53% versus 15%, respectively). The median ratio of the reference artery diameter to the stent diameter was 0.78, and patients whose ratio was smaller than 0.78 had a much higher incidence of ISR than patients whose ratio was larger than 0.78 (53% versus 15%, respectively). CONCLUSIONS: In our series, percutaneous transluminal angioplasty and stent placement of small intracranial arteries by using Wingspan stents was safe. The ISR rate was relatively high; most patients having ISR were asymptomatic. Further follow-up is needed to assess the long-term efficacy of this procedure.
Authors: Pierfrancesco Agostoni; Giuseppe G L Biondi-Zoccai; Gabriele L Gasparini; Maurizio Anselmi; Giorgio Morando; Marco Turri; Antonio Abbate; Eugene P McFadden; Corrado Vassanelli; Piero Zardini; Antonio Colombo; Patrick W Serruys Journal: Eur Heart J Date: 2005-01-28 Impact factor: 29.983
Authors: Michael M Chow; Thomas J Masaryk; Henry H Woo; Marc R Mayberg; Peter A Rasmussen Journal: AJNR Am J Neuroradiol Date: 2005-04 Impact factor: 3.825
Authors: Aquilla S Turk; Azam Ahmed; David B Niemann; Beverly Aagaard-Kienitz; Nathaniel Brooks; Ross L Levine Journal: Neuroradiology Date: 2007-03-27 Impact factor: 2.804
Authors: A S Turk; E I Levy; F C Albuquerque; G L Pride; H Woo; B G Welch; D B Niemann; P D Purdy; B Aagaard-Kienitz; P A Rasmussen; L N Hopkins; T J Masaryk; C G McDougall; D Fiorella Journal: AJNR Am J Neuroradiol Date: 2007-11-07 Impact factor: 3.825
Authors: O O Zaidat; R Klucznik; M J Alexander; J Chaloupka; H Lutsep; S Barnwell; M Mawad; B Lane; M J Lynn; M Chimowitz Journal: Neurology Date: 2008-01-30 Impact factor: 9.910
Authors: Colin P Derdeyn; David Fiorella; Michael J Lynn; Tanya N Turan; George A Cotsonis; Bethany F Lane; Jean Montgomery; L Scott Janis; Marc I Chimowitz Journal: Stroke Date: 2017-04-28 Impact factor: 7.914
Authors: David Fiorella; Colin P Derdeyn; Michael J Lynn; Stanley L Barnwell; Brian L Hoh; Elad I Levy; Mark R Harrigan; Richard P Klucznik; Cameron G McDougall; G Lee Pride; Osama O Zaidat; Helmi L Lutsep; Michael F Waters; J Maurice Hourihane; Andrei V Alexandrov; David Chiu; Joni M Clark; Mark D Johnson; Michel T Torbey; Zoran Rumboldt; Harry J Cloft; Tanya N Turan; Bethany F Lane; L Scott Janis; Marc I Chimowitz Journal: Stroke Date: 2012-09-13 Impact factor: 7.914