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Literature DB >> 22166995

Human pluripotent stem cells decouple respiration from energy production.

Ng Shyh-Chang¹, Yuxiang Zheng, Jason W Locasale, Lewis C Cantley.

Abstract

Entities: Species

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Year: 2011 PMID： 22166995 PMCID： PMC3242981 DOI： 10.1038/emboj.2011.436

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

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10 in total

1. The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells.

Authors: Alessandro Prigione; Beatrix Fauler; Rudi Lurz; Hans Lehrach; James Adjaye
Journal: Stem Cells Date: 2010-04 Impact factor: 6.277

2. Energetics and stoichiometry of oxidative phosphorylation from NADH to cytochrome c in isolated rat liver mitochondria.

Authors: N G Forman; D F Wilson
Journal: J Biol Chem Date: 1982-11-10 Impact factor: 5.157

3. Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

Authors: Clifford D L Folmes; Timothy J Nelson; Almudena Martinez-Fernandez; D Kent Arrell; Jelena Zlatkovic Lindor; Petras P Dzeja; Yasuhiro Ikeda; Carmen Perez-Terzic; Andre Terzic
Journal: Cell Metab Date: 2011-08-03 Impact factor: 27.287

4. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

Authors: Jin Zhang; Ivan Khvorostov; Jason S Hong; Yavuz Oktay; Laurent Vergnes; Esther Nuebel; Paulin N Wahjudi; Kiyoko Setoguchi; Geng Wang; Anna Do; Hea-Jin Jung; J Michael McCaffery; Irwin J Kurland; Karen Reue; Wai-Nang P Lee; Carla M Koehler; Michael A Teitell
Journal: EMBO J Date: 2011-11-15 Impact factor: 11.598

5. Reprogramming of human primary somatic cells by OCT4 and chemical compounds.

Authors: Saiyong Zhu; Wenlin Li; Hongyan Zhou; Wanguo Wei; Rajesh Ambasudhan; Tongxiang Lin; Janghwan Kim; Kang Zhang; Sheng Ding
Journal: Cell Stem Cell Date: 2010-12-03 Impact factor: 24.633

Review 6. Uncoupling protein UCP2: when mitochondrial activity meets immunity.

Authors: Yalin Emre; Tobias Nübel
Journal: FEBS Lett Date: 2010-03-15 Impact factor: 4.124

7. Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

Authors: Matthew G Vander Heiden; Jason W Locasale; Kenneth D Swanson; Hadar Sharfi; Greg J Heffron; Daniel Amador-Noguez; Heather R Christofk; Gerhard Wagner; Joshua D Rabinowitz; John M Asara; Lewis C Cantley
Journal: Science Date: 2010-09-17 Impact factor: 47.728

8. No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.

Authors: Elodie Couplan; Maria del Mar Gonzalez-Barroso; Marie Clotilde Alves-Guerra; Daniel Ricquier; Marc Goubern; Frédéric Bouillaud
Journal: J Biol Chem Date: 2002-05-14 Impact factor: 5.157

9. Mitochondrial DNA replication during differentiation of murine embryonic stem cells.

Authors: Joao M Facucho-Oliveira; Jon Alderson; Emma C Spikings; Stuart Egginton; Justin C St John
Journal: J Cell Sci Date: 2007-10-30 Impact factor: 5.285

10. Why do tumor cells have a high aerobic glycolysis?

Authors: E Racker
Journal: J Cell Physiol Date: 1976-12 Impact factor: 6.384

10 in total

17 in total

Human pluripotent stem cells decouple respiration from energy production.

1. The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells.

2. Energetics and stoichiometry of oxidative phosphorylation from NADH to cytochrome c in isolated rat liver mitochondria.

3. Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

4. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

5. Reprogramming of human primary somatic cells by OCT4 and chemical compounds.

Review 6. Uncoupling protein UCP2: when mitochondrial activity meets immunity.

7. Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

8. No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.

9. Mitochondrial DNA replication during differentiation of murine embryonic stem cells.

10. Why do tumor cells have a high aerobic glycolysis?

Review 1. Energy metabolism in the acquisition and maintenance of stemness.

2. Metabolome and metaboproteome remodeling in nuclear reprogramming.

Review 3. Stem cell metabolism in tissue development and aging.

Review 4. Metabolic requirements for the maintenance of self-renewing stem cells.

Review 5. Metabolic restructuring and cell fate conversion.

6. Enhanced tissue production through redox control in stem cell-laden hydrogels.

Review 7. Anticancer agents that counteract tumor glycolysis.

Review 8. Metabolic control of cancer cell stemness: Lessons from iPS cells.

9. Evolution of natural agents: preservation, advance, and emergence of functional information.

10. Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal.