Literature DB >> 23122286

Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal.

Jin Zhang1, Esther Nuebel, George Q Daley, Carla M Koehler, Michael A Teitell.   

Abstract

Small, rapidly dividing pluripotent stem cells (PSCs) have unique energetic and biosynthetic demands compared with typically larger, quiescent differentiated cells. Shifts between glycolysis and oxidative phosphorylation with PSC differentiation or reprogramming to pluripotency are accompanied by changes in cell cycle, biomass, metabolite levels, and redox state. PSC and cancer cell metabolism are overtly similar, with metabolite levels influencing epigenetic/genetic programs. Here, we discuss the emerging roles for metabolism in PSC self-renewal, differentiation, and reprogramming.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2012        PMID： 23122286      PMCID： PMC3492890          DOI： 10.1016/j.stem.2012.10.005

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  54 in total

1.  On the origin of cancer cells.

Authors:  O WARBURG
Journal:  Science       Date:  1956-02-24       Impact factor: 47.728

2.  Connecting threads: epigenetics and metabolism.

Authors:  Sayako Katada; Axel Imhof; Paolo Sassone-Corsi
Journal:  Cell       Date:  2012-01-20       Impact factor: 41.582

3.  The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway.

Authors:  Min Fang; Zhirong Shen; Song Huang; Liping Zhao; She Chen; Tak W Mak; Xiaodong Wang
Journal:  Cell       Date:  2010-11-11       Impact factor: 41.582

4.  Core transcriptional regulatory circuitry in human embryonic stem cells.

Authors:  Laurie A Boyer; Tong Ihn Lee; Megan F Cole; Sarah E Johnstone; Stuart S Levine; Jacob P Zucker; Matthew G Guenther; Roshan M Kumar; Heather L Murray; Richard G Jenner; David K Gifford; Douglas A Melton; Rudolf Jaenisch; Richard A Young
Journal:  Cell       Date:  2005-09-23       Impact factor: 41.582

5.  Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.

Authors:  Kathrin Zaugg; Yi Yao; Patrick T Reilly; Karuppiah Kannan; Reza Kiarash; Jacqueline Mason; Ping Huang; Suzanne K Sawyer; Benjamin Fuerth; Brandon Faubert; Tuula Kalliomäki; Andrew Elia; Xunyi Luo; Vincent Nadeem; David Bungard; Sireesha Yalavarthi; Joseph D Growney; Andrew Wakeham; Yasmin Moolani; Jennifer Silvester; Annick You Ten; Walbert Bakker; Katsuya Tsuchihara; Shelley L Berger; Richard P Hill; Russell G Jones; Ming Tsao; Murray O Robinson; Craig B Thompson; Guohua Pan; Tak W Mak
Journal:  Genes Dev       Date:  2011-05-15       Impact factor: 11.361

6.  Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

Authors:  Clifford D L Folmes; Timothy J Nelson; Almudena Martinez-Fernandez; D Kent Arrell; Jelena Zlatkovic Lindor; Petras P Dzeja; Yasuhiro Ikeda; Carmen Perez-Terzic; Andre Terzic
Journal:  Cell Metab       Date:  2011-08-03       Impact factor: 27.287

7.  Metabolic oxidation regulates embryonic stem cell differentiation.

Authors:  Oscar Yanes; Julie Clark; Diana M Wong; Gary J Patti; Antonio Sánchez-Ruiz; H Paul Benton; Sunia A Trauger; Caroline Desponts; Sheng Ding; Gary Siuzdak
Journal:  Nat Chem Biol       Date:  2010-05-02       Impact factor: 15.040

8.  Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress.

Authors:  Stefania Filosa; Annalisa Fico; Francesca Paglialunga; Marco Balestrieri; Almudena Crooke; Pasquale Verde; Paolo Abrescia; José M Bautista; Giuseppe Martini
Journal:  Biochem J       Date:  2003-03-15       Impact factor: 3.857

9.  Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

Authors:  Wei Xu; Hui Yang; Ying Liu; Ying Yang; Ping Wang; Se-Hee Kim; Shinsuke Ito; Chen Yang; Pu Wang; Meng-Tao Xiao; Li-xia Liu; Wen-qing Jiang; Jing Liu; Jin-ye Zhang; Bin Wang; Stephen Frye; Yi Zhang; Yan-hui Xu; Qun-ying Lei; Kun-Liang Guan; Shi-min Zhao; Yue Xiong
Journal:  Cancer Cell       Date:  2011-01-18       Impact factor: 38.585

10.  Direct cell reprogramming is a stochastic process amenable to acceleration.

Authors:  Jacob Hanna; Krishanu Saha; Bernardo Pando; Jeroen van Zon; Christopher J Lengner; Menno P Creyghton; Alexander van Oudenaarden; Rudolf Jaenisch
Journal:  Nature       Date:  2009-11-08       Impact factor: 49.962
View more
  193 in total

1.  Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs.

Authors:  Chenlin Zhou; Xiaoqin Yang; Yiyang Sun; Hongyao Yu; Yong Zhang; Ying Jin
Journal:  Cell Res       Date:  2016-01-26       Impact factor: 25.617

Review 2.  Molecular features of cellular reprogramming and development.

Authors:  Zachary D Smith; Camille Sindhu; Alexander Meissner
Journal:  Nat Rev Mol Cell Biol       Date:  2016-02-17       Impact factor: 94.444

3.  Advances in Applications of Metabolomics in Pluripotent Stem Cell Research.

Authors:  Vijesh J Bhute; Xiaoping Bao; Sean P Palecek
Journal:  Curr Opin Chem Eng       Date:  2016-12-15       Impact factor: 5.163

4.  Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling.

Authors:  Sriram Chandrasekaran; Jin Zhang; Zhen Sun; Li Zhang; Christian A Ross; Yu-Chung Huang; John M Asara; Hu Li; George Q Daley; James J Collins
Journal:  Cell Rep       Date:  2017-12-05       Impact factor: 9.423

5.  Emergence of spatial structure in the tumor microenvironment due to the Warburg effect.

Authors:  Carlos Carmona-Fontaine; Vanni Bucci; Leila Akkari; Maxime Deforet; Johanna A Joyce; Joao B Xavier
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-11       Impact factor: 11.205

6.  Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging.

Authors:  Liana R Stein; Shin-ichiro Imai
Journal:  EMBO J       Date:  2014-05-08       Impact factor: 11.598

7.  Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis.

Authors:  Young Cha; Min-Joon Han; Hyuk-Jin Cha; Janet Zoldan; Alison Burkart; Jin Hyuk Jung; Yongwoo Jang; Chun-Hyung Kim; Ho-Chang Jeong; Byung-Gyu Kim; Robert Langer; C Ronald Kahn; Leonard Guarente; Kwang-Soo Kim
Journal:  Nat Cell Biol       Date:  2017-04-24       Impact factor: 28.824

Review 8.  Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cells.

Authors:  Amparo Beltran-Povea; Estefania Caballano-Infantes; Carmen Salguero-Aranda; Franz Martín; Bernat Soria; Francisco J Bedoya; Juan R Tejedo; Gladys M Cahuana
Journal:  World J Stem Cells       Date:  2015-04-26       Impact factor: 5.326

9.  The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.

Authors:  Jean-Pierre Etchegaray; Lukas Chavez; Yun Huang; Kenneth N Ross; Jiho Choi; Barbara Martinez-Pastor; Ryan M Walsh; Cesar A Sommer; Matthias Lienhard; Adrianne Gladden; Sita Kugel; Dafne M Silberman; Sridhar Ramaswamy; Gustavo Mostoslavsky; Konrad Hochedlinger; Alon Goren; Anjana Rao; Raul Mostoslavsky
Journal:  Nat Cell Biol       Date:  2015-04-27       Impact factor: 28.824

10.  ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance.

Authors:  Kun Liu; Qian Zhao; Pinglei Liu; Jiani Cao; Jiaqi Gong; Chaoqun Wang; Weixu Wang; Xiaoyan Li; Hongyan Sun; Chao Zhang; Yufei Li; Minggui Jiang; Shaohua Zhu; Qingyuan Sun; Jianwei Jiao; Baoyang Hu; Xiaoyang Zhao; Wei Li; Quan Chen; Qi Zhou; Tongbiao Zhao
Journal:  Autophagy       Date:  2016-08-11       Impact factor: 16.016
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.