Literature DB >> 22085394

Parenting through genetic uncertainty: themes in the disclosure of breast cancer risk information to children.

McKane E Sharff1, Tiffani A DeMarco, Darren Mays, Beth N Peshkin, Heiddis B Valdimarsdottir, Judy E Garber, Katherine A Schneider, Andrea F Patenaude, Kenneth P Tercyak.   

Abstract

AIM: Among mothers undergoing BRCA1/2 testing and their spouses/partners, this study sought to examine decision support needs and motivations for family communication of genetic risk information to asymptomatic children.
METHODS: This study gathered data from 213 tested mothers and 104 of their untested parenting partners 1 month after maternal receipt of genetic test results and upon making a decision about communicating genetic information to their child (ages 8-21 years). Data include parents' perceived needs for family communication decision support, decision motivations, and parent-child communication.
RESULTS: Parents reported high decision support needs (e.g., educational materials, professional counseling, peer assistance). Motivations for disclosure to children among mothers and partners focused on promoting the parent-child bond and maintaining family health (55.3% and 75%, respectively) and promoting positive child affect (44.7% and 25.5%, respectively). Motivations for nondisclosure to children among mothers and partners focused on the lack of appropriateness (69.6% and 51.3%, respectively) and relative importance of genetic test results (30.4% and 48.7%, respectively). Significant discrepancies in parental motivation for family communication were observed. Decision support needs were highest among disclosing mothers with affect-related motivations [t (129)=2.47; p=0.01]. Parent-child communication was poorest among nondisclosing mothers concerned about the appropriateness of genetic information for their child [t (77)=-3.29; p=.002].
CONCLUSIONS: Parents receiving information about hereditary cancer predisposition have unmet needs when making decisions about disclosing genetic risk information to their asymptomatic children. These data can guide the development of cancer risk communication decision support interventions for parents undergoing such testing.

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Year:  2011        PMID: 22085394      PMCID: PMC3354582          DOI: 10.1089/gtmb.2011.0154

Source DB:  PubMed          Journal:  Genet Test Mol Biomarkers        ISSN: 1945-0257


  25 in total

1.  Parent opinions regarding the genetic testing of minors for BRCA1/2.

Authors:  Angela R Bradbury; Linda Patrick-Miller; Brian Egleston; Colleen Burke Sands; Tianyu Li; Helen Schmidheiser; Maia Feigon; Comfort N Ibe; Fay J Hlubocky; Kisha Hope; Sarah Jackson; Melanie Corbman; Olufunmilayo I Olopade; Mary Daly; Christopher K Daugherty
Journal:  J Clin Oncol       Date:  2010-06-21       Impact factor: 44.544

2.  Parental communication of BRCA1/2 genetic test results to children.

Authors:  K P Tercyak; C Hughes; D Main; C Snyder; J F Lynch; H T Lynch; C Lerman
Journal:  Patient Educ Couns       Date:  2001-03

3.  Communication of BRCA results and family testing in 1,103 high-risk women.

Authors:  Eleanor L Cheung; Ashley D Olson; Tina M Yu; Pamela Z Han; Mary S Beattie
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2010-08-10       Impact factor: 4.254

4.  To tell or not to tell: barriers and facilitators in family communication about genetic risk.

Authors:  K Forrest; S A Simpson; B J Wilson; E R van Teijlingen; L McKee; N Haites; E Matthews
Journal:  Clin Genet       Date:  2003-10       Impact factor: 4.438

5.  On the development of a decision support intervention for mothers undergoing BRCA1/2 cancer genetic testing regarding communicating test results to their children.

Authors:  Beth N Peshkin; Tiffani A Demarco; Kenneth P Tercyak
Journal:  Fam Cancer       Date:  2009-07-17       Impact factor: 2.375

6.  American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility.

Authors: 
Journal:  J Clin Oncol       Date:  2003-04-11       Impact factor: 44.544

7.  An investigation of the disclosure process and support needs of BRCA1 and BRCA2 carriers.

Authors:  Jordana Segal; Mary Jane Esplen; Brenda Toner; Sylvia Baedorf; Steven Narod; Kate Butler
Journal:  Am J Med Genet A       Date:  2004-03-15       Impact factor: 2.802

8.  Information needs of mothers regarding communicating BRCA1/2 cancer genetic test results to their children.

Authors:  Kenneth P Tercyak; Beth N Peshkin; Tiffani A Demarco; Andrea Farkas Patenaude; Katherine A Schneider; Judy E Garber; Heiddis B Valdimarsdottir; Marc D Schwartz
Journal:  Genet Test       Date:  2007

9.  Prevalence and correlates of mothers and fathers attending pretest cancer genetic counseling together.

Authors:  Tiffani A Demarco; Rachel H Nusbaum; Beth N Peshkin; Andrea F Patenaude; Katherine A Schneider; Judy E Garber; Heiddis B Valdimarsdottir; Kenneth P Tercyak
Journal:  Patient Educ Couns       Date:  2009-07-09

10.  Parent-child factors and their effect on communicating BRCA1/2 test results to children.

Authors:  Kenneth P Tercyak; Beth N Peshkin; Tiffani A DeMarco; Barbara M Brogan; Caryn Lerman
Journal:  Patient Educ Couns       Date:  2002-06
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  12 in total

1.  Effects of undergoing multiplex genetic susceptibility testing on parent attitudes towards testing their children.

Authors:  Anne C Madeo; Kenneth P Tercyak; Beth A Tarini; Colleen M McBride
Journal:  Ann Behav Med       Date:  2014-06

2.  Distress and the parenting dynamic among BRCA1/2 tested mothers and their partners.

Authors:  Darren Mays; Tiffani A DeMarco; George Luta; Beth N Peshkin; Andrea F Patenaude; Katherine A Schneider; Judy E Garber; Kenneth P Tercyak
Journal:  Health Psychol       Date:  2013-06-24       Impact factor: 4.267

3.  Decisional outcomes of maternal disclosure of BRCA1/2 genetic test results to children.

Authors:  Kenneth P Tercyak; Darren Mays; Tiffani A DeMarco; Beth N Peshkin; Heiddis B Valdimarsdottir; Katherine A Schneider; Judy E Garber; Andrea Farkas Patenaude
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2013-07       Impact factor: 4.254

4.  Cancer genetic health communication in families tested for hereditary breast/ovarian cancer risk: a qualitative investigation of impact on children's genetic health literacy and psychosocial adjustment.

Authors:  Kenneth P Tercyak; Suzanne M Bronheim; Nicole Kahn; Hillary A Robertson; Bruno J Anthony; Darren Mays; Suzanne C O'Neill; Susan K Peterson; Susan Miesfeldt; Beth N Peshkin; Tiffani A DeMarco
Journal:  Transl Behav Med       Date:  2019-05-16       Impact factor: 3.046

5.  Development of a Tool to Guide Parents Carrying a BRCA1/2 Mutation Share Genetic Results with Underage Children.

Authors:  Ariane Santerre-Theil; Karine Bouchard; Dominique St-Pierre; Anne-Marie Drolet; Jocelyne Chiquette; Michel Dorval
Journal:  J Cancer Educ       Date:  2018-06       Impact factor: 2.037

Review 6.  Genetic risk assessments in individuals at high risk for inherited breast cancer in the breast oncology care setting.

Authors:  Tuya Pal; Susan T Vadaparampil
Journal:  Cancer Control       Date:  2012-10       Impact factor: 3.302

7.  Talking to children about maternal BRCA1/2 genetic test results: a qualitative study of parental perceptions and advice.

Authors:  Andrea Farkas Patenaude; Tiffani A DeMarco; Beth N Peshkin; Heiddis Valdimarsdottir; Judy E Garber; Katherine A Schneider; Larissa Hewitt; Jennifer Hamilton; Kenneth P Tercyak
Journal:  J Genet Couns       Date:  2012-10-24       Impact factor: 2.537

8.  Women's concerns about the emotional impact of awareness of heritable breast cancer risk and its implications for their children.

Authors:  Suzanne C O'Neill; Darren Mays; Andrea Farkas Patenaude; Judy E Garber; Tiffani A DeMarco; Beth N Peshkin; Katherine A Schneider; Kenneth P Tercyak
Journal:  J Community Genet       Date:  2014-08-07

9.  Communicating with Daughters About Familial Risk of Breast Cancer: Individual, Family, and Provider Influences on Women's Knowledge of Cancer Risk.

Authors:  Lucy A Peipins; Juan L Rodriguez; Nikki A Hawkins; Ashwini Soman; Mary C White; M Elizabeth Hodgson; Lisa A DeRoo; Dale P Sandler
Journal:  J Womens Health (Larchmt)       Date:  2018-01-29       Impact factor: 2.681

10.  Psychometric properties of the Pediatric Testing Attitudes Scale-Diabetes (P-TAS-D) for parents of children undergoing predictive risk screening.

Authors:  Kenneth P Tercyak; Darren Mays; Suzanne Bennett Johnson; Johnny Ludvigsson; Ulrica Swartling
Journal:  Pediatr Diabetes       Date:  2013-06-14       Impact factor: 4.866

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