Literature DB >> 24338635

Effects of undergoing multiplex genetic susceptibility testing on parent attitudes towards testing their children.

Anne C Madeo1, Kenneth P Tercyak, Beth A Tarini, Colleen M McBride.   

Abstract

BACKGROUND: Parents may pursue common disease risk information about themselves via multiplex genetic susceptibility testing (MGST) for their children.
PURPOSE: To prospectively assess whether parents who received MGST disclosed their test results to their child, intended to change the child's health habits, or have the child tested.
METHODS: Eighty parents who opted for free MGST completed an online survey about a child in their household before undergoing MGST and a follow-up telephone survey 3 months after receiving results.
RESULTS: Few parents (21 %) disclosed results to the child. Undergoing MGST was unrelated to intentions to change the child's health habits but did increase parental willingness to test the child. Greater willingness to test a child was associated with positive attitudes toward pediatric genetic testing and intentions to change the child's health habits.
CONCLUSION: The experience of receiving MGST had little impact on parents' perceptions or behaviors related to their minor child.

Entities:  

Mesh:

Year:  2014        PMID: 24338635      PMCID: PMC4008655          DOI: 10.1007/s12160-013-9553-z

Source DB:  PubMed          Journal:  Ann Behav Med        ISSN: 0883-6612


  18 in total

Review 1.  The visual communication of risk.

Authors:  I M Lipkus; J G Hollands
Journal:  J Natl Cancer Inst Monogr       Date:  1999

2.  Participation in genetic testing research varies by social group.

Authors:  Sharon Hensley Alford; Colleen M McBride; Robert J Reid; Eric B Larson; Andreas D Baxevanis; Lawrence C Brody
Journal:  Public Health Genomics       Date:  2010-03-18       Impact factor: 2.000

3.  Parents' attitudes toward pediatric genetic testing for common disease risk.

Authors:  Kenneth P Tercyak; Sharon Hensley Alford; Karen M Emmons; Isaac M Lipkus; Benjamin S Wilfond; Colleen M McBride
Journal:  Pediatrics       Date:  2011-04-18       Impact factor: 7.124

4.  Effect of direct-to-consumer genomewide profiling to assess disease risk.

Authors:  Cinnamon S Bloss; Nicholas J Schork; Eric J Topol
Journal:  N Engl J Med       Date:  2011-01-12       Impact factor: 91.245

5.  Parenting through genetic uncertainty: themes in the disclosure of breast cancer risk information to children.

Authors:  McKane E Sharff; Tiffani A DeMarco; Darren Mays; Beth N Peshkin; Heiddis B Valdimarsdottir; Judy E Garber; Katherine A Schneider; Andrea F Patenaude; Kenneth P Tercyak
Journal:  Genet Test Mol Biomarkers       Date:  2011-11-15

6.  Consumers' use of web-based information and their decisions about multiplex genetic susceptibility testing.

Authors:  Kimberly A Kaphingst; Colleen M McBride; Christopher Wade; Sharon Hensley Alford; Lawrence C Brody; Andreas D Baxevanis
Journal:  J Med Internet Res       Date:  2010-09-29       Impact factor: 5.428

7.  Considerations for designing a prototype genetic test for use in translational research.

Authors:  C H Wade; C M McBride; S L R Kardia; L C Brody
Journal:  Public Health Genomics       Date:  2009-09-03       Impact factor: 2.000

8.  Patients' understanding of and responses to multiplex genetic susceptibility test results.

Authors:  Kimberly A Kaphingst; Colleen M McBride; Christopher Wade; Sharon Hensley Alford; Robert Reid; Eric Larson; Andreas D Baxevanis; Lawrence C Brody
Journal:  Genet Med       Date:  2012-07       Impact factor: 8.822

Review 9.  Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours.

Authors:  Theresa M Marteau; David P French; Simon J Griffin; A T Prevost; Stephen Sutton; Clare Watkinson; Sophie Attwood; Gareth J Hollands
Journal:  Cochrane Database Syst Rev       Date:  2010-10-06

10.  Characteristics of users of online personalized genomic risk assessments: implications for physician-patient interactions.

Authors:  Colleen M McBride; Sharon Hensley Alford; Robert J Reid; Eric B Larson; Andreas D Baxevanis; Lawrence C Brody
Journal:  Genet Med       Date:  2009-08       Impact factor: 8.822

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