Literature DB >> 22047353

A PENELOPE-based system for the automated Monte Carlo simulation of clinacs and voxelized geometries-application to far-from-axis fields.

Josep Sempau1, Andreu Badal, Lorenzo Brualla.   

Abstract

PURPOSE: Two new codes, PENEASY and PENEASYLINAC, which automate the Monte Carlo simulation of Varian Clinacs of the 600, 1800, 2100, and 2300 series, together with their electron applicators and multileaf collimators, are introduced. The challenging case of a relatively small and far-from-axis field has been studied with these tools.
METHODS: PENEASY is a modular, general-purpose main program for the PENELOPE Monte Carlo system that includes various source models, tallies and variance-reduction techniques (VRT). The code includes a new geometry model that allows the superposition of voxels and objects limited by quadric surfaces. A variant of the VRT known as particle splitting, called fan splitting, is also introduced. PENEASYLINAC, in turn, automatically generates detailed geometry and configuration files to simulate linacs with PENEASY. These tools are applied to the generation of phase-space files, and of the corresponding absorbed dose distributions in water, for two 6 MV photon beams from a Varian Clinac 2100 C∕D: a 40 × 40 cm(2) centered field; and a 3 × 5 cm(2) field centered at (4.5, -11.5) cm from the beam central axis. This latter configuration implies the largest possible over-traveling values of two of the jaws. Simulation results for the depth dose and lateral profiles at various depths are compared, by using the gamma index, with experimental values obtained with a PTW 31002 ionization chamber. The contribution of several VRTs to the computing speed of the more demanding off-axis case is analyzed.
RESULTS: For the 40 × 40 cm(2) field, the percentages γ(1) and γ(1.2) of voxels with gamma indices (using 0.2 cm and 2% criteria) larger than unity and larger than 1.2 are 0.2% and 0%, respectively. For the 3 × 5 cm(2) field, γ(1) = 0%. These figures indicate an excellent agreement between simulation and experiment. The dose distribution for the off-axis case with voxels of 2.5 × 2.5 × 2.5 mm(3) and an average standard statistical uncertainty of 2% (1σ) is computed in 3.1 h on a single core of a 2.8 GHz Intel Core 2 Duo processor. This result is obtained with the optimal combination of the tested VRTs. In particular, fan splitting for the off-axis case accelerates execution by a factor of 240 with respect to standard particle splitting.
CONCLUSIONS: PENEASY and PENEASYLINAC can simulate the considered Varian Clinacs both in an accurate and efficient manner. Fan splitting is crucial to achieve simulation results for the off-axis field in an affordable amount of CPU time. Work to include Elekta linacs and to develop a graphical interface that will facilitate user input is underway.

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Year:  2011        PMID: 22047353     DOI: 10.1118/1.3643029

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  26 in total

1.  PRIMO: a graphical environment for the Monte Carlo simulation of Varian and Elekta linacs.

Authors:  M Rodriguez; J Sempau; L Brualla
Journal:  Strahlenther Onkol       Date:  2013-09-06       Impact factor: 3.621

2.  Characterization of scatter magnitude and distribution in dedicated breast computed tomography with bowtie filters.

Authors:  Kimberly Kontson; Robert J Jennings
Journal:  J Med Imaging (Bellingham)       Date:  2014-12-18

Review 3.  Monte Carlo systems used for treatment planning and dose verification.

Authors:  Lorenzo Brualla; Miguel Rodriguez; Antonio M Lallena
Journal:  Strahlenther Onkol       Date:  2016-11-25       Impact factor: 3.621

4.  The potential impact of ultrathin filter design on dosimetry and relative biological effectiveness in modern image-guided small animal irradiators.

Authors:  Yannick Poirier; Christopher Daniel Johnstone; Charles Kirkby
Journal:  Br J Radiol       Date:  2018-11-15       Impact factor: 3.039

5.  A virtual trial framework for quantifying the detectability of masses in breast tomosynthesis projection data.

Authors:  Stefano Young; Predrag R Bakic; Kyle J Myers; Robert J Jennings; Subok Park
Journal:  Med Phys       Date:  2013-05       Impact factor: 4.071

6.  Monte Carlo Estimation of Absorbed Dose Distributions Obtained from Heterogeneous 106Ru Eye Plaques.

Authors:  Francisco J Zaragoza; Marion Eichmann; Dirk Flühs; Wolfgang Sauerwein; Lorenzo Brualla
Journal:  Ocul Oncol Pathol       Date:  2017-02-23

7.  Characterization and validation of the thorax phantom Lungman for dose assessment in chest radiography optimization studies.

Authors:  Sunay Rodríguez Pérez; Nicholas William Marshall; Lara Struelens; Hilde Bosmans
Journal:  J Med Imaging (Bellingham)       Date:  2018-02-06

8.  Accurate estimation of dose distributions inside an eye irradiated with 106Ru plaques.

Authors:  L Brualla; J Sempau; F J Zaragoza; A Wittig; W Sauerwein
Journal:  Strahlenther Onkol       Date:  2012-11-18       Impact factor: 3.621

9.  Monte Carlo Simulation of the Treatment of Eye Tumors with (106)Ru Plaques: A Study on Maximum Tumor Height and Eccentric Placement.

Authors:  Lorenzo Brualla; Francisco J Zaragoza; Wolfgang Sauerwein
Journal:  Ocul Oncol Pathol       Date:  2014-05-07

10.  Geometrical splitting technique to improve the computational efficiency in Monte Carlo calculations for proton therapy.

Authors:  José Ramos-Méndez; Joseph Perl; Bruce Faddegon; Jan Schümann; Harald Paganetti
Journal:  Med Phys       Date:  2013-04       Impact factor: 4.071

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