Literature DB >> 22027317

FlexTouch: a prefilled insulin pen with a novel injection mechanism with consistent high accuracy at low- (1 U), medium- (40 U), and high- (80 U) dose settings.

Jakob Oest Wielandt1, Marcus Niemeyer, Marianne Rye Hansen, Ditlef Bucher, Niels Bjerrum Thomsen.   

Abstract

BACKGROUND: FlexTouch® is the only prefilled insulin pen that utilizes an easy touch button that does not extend at any dose in place of a push-button extension. Rigorous testing has shown that the new FlexTouch pen accurately and consistently delivers insulin doses.
METHODS: This study assessed dose accuracy of FlexTouch, KwikPen®, and SoloSTAR®. Dose accuracy for minimum, medium, and maximum doses of each pen type (1, 40, and 80 U for FlexTouch and SoloSTAR and 1, 30, and 60 U for KwikPen) was assessed.
RESULTS: FlexTouch delivered all doses consistently, as demonstrated by low standard deviations. FlexTouch showed similar accuracy to KwikPen at 1 U and to SoloSTAR at 40 and 80 U. However, FlexTouch was significantly more accurate at delivering 1 U of insulin than SoloSTAR (p < .0001).
CONCLUSIONS: This study demonstrates that FlexTouch, a new prefilled pen, delivers insulin accurately and consistently at low, medium, and high doses. In addition, FlexTouch is currently the only prefilled pen that has a push button that does not extend at any dose, making FlexTouch easier to use than other pens.
© 2011 Diabetes Technology Society.

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Year:  2011        PMID: 22027317      PMCID: PMC3208880          DOI: 10.1177/193229681100500525

Source DB:  PubMed          Journal:  J Diabetes Sci Technol        ISSN: 1932-2968


  19 in total

1.  Dosing accuracy of two insulin pre-filled pens.

Authors:  Toshinari Asakura; Hiroaki Seino; Miho Kageyama; Noriaki Yohkoh
Journal:  Curr Med Res Opin       Date:  2008-04-08       Impact factor: 2.580

2.  Injection related anxiety in insulin-treated diabetes.

Authors:  A Zambanini; R B Newson; M Maisey; M D Feher
Journal:  Diabetes Res Clin Pract       Date:  1999-12       Impact factor: 5.602

3.  Phobia of self-injecting and self-testing in insulin-treated diabetes patients: opportunities for screening.

Authors:  E D Mollema; F J Snoek; R J Heine; H M van der Ploeg
Journal:  Diabet Med       Date:  2001-08       Impact factor: 4.359

Review 4.  Insulin delivery using pen devices. Simple-to-use tools may help young and old alike.

Authors:  N J Bohannon
Journal:  Postgrad Med       Date:  1999-10-15       Impact factor: 3.840

5.  Medication adherence and the associated health-economic impact among patients with type 2 diabetes mellitus converting to insulin pen therapy: an analysis of third-party managed care claims data.

Authors:  Won Chan Lee; Sanjeev Balu; David Cobden; Ashish V Joshi; Chris L Pashos
Journal:  Clin Ther       Date:  2006-10       Impact factor: 3.393

6.  FlexPen for the delivery of insulin: accuracy, injection force and patient preference.

Authors:  Andreas Pfützner
Journal:  Expert Rev Med Devices       Date:  2009-03       Impact factor: 3.166

7.  Prefilled insulin device with reduced injection force: patient perception and accuracy.

Authors:  A Pfützner; T Reimer; C Hohberg; L P F Frøkjaer; C Jørgensen
Journal:  Curr Med Res Opin       Date:  2008-07-31       Impact factor: 2.580

8.  Improvement in health-related quality of life, independent of fasting glucose concentration, via insulin pen device in diabetic patients.

Authors:  I-Te Lee; Hsiu-Chen Liu; Yi-Ju Liau; Wen-Jane Lee; Chien-Ning Huang; Wayne Huey-Herng Sheu
Journal:  J Eval Clin Pract       Date:  2009-08       Impact factor: 2.431

9.  Accuracy and reproducibility of low dose insulin administration using pen-injectors and syringes.

Authors:  M G Gnanalingham; P Newland; C P Smith
Journal:  Arch Dis Child       Date:  1998-07       Impact factor: 3.791

Review 10.  Needle phobia: a neglected diagnosis.

Authors:  J G Hamilton
Journal:  J Fam Pract       Date:  1995-08       Impact factor: 0.493

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  7 in total

1.  Making life easier for insulin users: one step forward with incremental advances in insulin delivery systems.

Authors:  John Paul Lock
Journal:  J Diabetes Sci Technol       Date:  2011-09-01

2.  Dosing Accuracy of Two Disposable Insulin Pens According to New ISO 11608-1: 2012 Requirements.

Authors:  Mona Abdel-Tawab; Mario Schmitz; Stefan Kamlot; Manfred Schubert-Zsilavecz
Journal:  J Diabetes Sci Technol       Date:  2015-07-17

3.  The value of fast-acting insulin aspart compared with insulin aspart for patients with diabetes mellitus treated with bolus insulin from a UK health care system perspective.

Authors:  Lalantha Leelarathna; Donna Ashley; Carrie Fidler; Witesh Parekh
Journal:  Ther Adv Endocrinol Metab       Date:  2018-04-04       Impact factor: 3.565

Review 4.  The Review of Insulin Pens-Past, Present, and Look to the Future.

Authors:  Małgorzata Masierek; Katarzyna Nabrdalik; Oliwia Janota; Hanna Kwiendacz; Maksymilian Macherski; Janusz Gumprecht
Journal:  Front Endocrinol (Lausanne)       Date:  2022-03-08       Impact factor: 5.555

5.  Development of an Insulin Pen is a Patient-Centric Multidisciplinary Undertaking: A Commentary.

Authors:  Thomas Sparre; Niels-Aage B Hansen; Anya Sonia Wernersson; Mark Guarraia
Journal:  J Diabetes Sci Technol       Date:  2021-12-01

6.  A comparison study of patient ratings and safety of 32- and 34-gauge insulin pen needles.

Authors:  Satoru Yamada; Yoshifumi Yamada; Yoko Tsukamoto; Mitsuhisa Tabata; Junichiro Irie
Journal:  Diabetol Int       Date:  2015-10-28

Review 7.  Evolution of Insulin Delivery Devices: From Syringes, Pens, and Pumps to DIY Artificial Pancreas.

Authors:  Jothydev Kesavadev; Banshi Saboo; Meera B Krishna; Gopika Krishnan
Journal:  Diabetes Ther       Date:  2020-05-14       Impact factor: 2.945

  7 in total

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