AIM: To determine if anesthesiologist-monitored use of propofol results in improved detection of adenomas when compared with routine conscious sedation. METHODS: This retrospective study was conducted at two separate hospital-based endoscopy units where approximately 12,000 endoscopic procedures are performed annually, with one endoscopy unit exclusively using anesthesiologist-monitored propofol. Three thousand two hundred and fifty-two patients underwent initial screening or surveillance colonoscopies. Our primary end point was the adenoma detection rate, defined as the number of patients in whom at least one adenoma was found, associated with the type of sedation. RESULTS: Three thousand two hundred and fifty-two outpatient colonoscopies were performed by five selected endoscopists. At least one adenoma was detected in 27.6% of patients (95% CI = 26.0-29.1) with no difference in the detection rate between the anesthesiologist-propofol and group and the gastroenterologist-midazolam/fentanyl group (28.1% vs 27.1%, P = 0.53). CONCLUSION: The type of sedation used during colonoscopy does not affect the number of patients in whom adenomatous polyps are detected.
AIM: To determine if anesthesiologist-monitored use of propofol results in improved detection of adenomas when compared with routine conscious sedation. METHODS: This retrospective study was conducted at two separate hospital-based endoscopy units where approximately 12,000 endoscopic procedures are performed annually, with one endoscopy unit exclusively using anesthesiologist-monitored propofol. Three thousand two hundred and fifty-two patients underwent initial screening or surveillance colonoscopies. Our primary end point was the adenoma detection rate, defined as the number of patients in whom at least one adenoma was found, associated with the type of sedation. RESULTS: Three thousand two hundred and fifty-two outpatient colonoscopies were performed by five selected endoscopists. At least one adenoma was detected in 27.6% of patients (95% CI = 26.0-29.1) with no difference in the detection rate between the anesthesiologist-propofol and group and the gastroenterologist-midazolam/fentanyl group (28.1% vs 27.1%, P = 0.53). CONCLUSION: The type of sedation used during colonoscopy does not affect the number of patients in whom adenomatous polyps are detected.
Authors: Douglas O Faigel; Irving M Pike; Todd H Baron; Amitabh Chak; Jonathan Cohen; Stephen E Deal; Brenda Hoffman; Brian C Jacobson; Klaus Mergener; Bret T Petersen; John L Petrini; Douglas K Rex; Michael A Safdi Journal: Gastrointest Endosc Date: 2006-04 Impact factor: 9.427
Authors: D K Rex; C S Cutler; G T Lemmel; E Y Rahmani; D W Clark; D J Helper; G A Lehman; D G Mark Journal: Gastroenterology Date: 1997-01 Impact factor: 22.682
Authors: Bernard Levin; David A Lieberman; Beth McFarland; Kimberly S Andrews; Durado Brooks; John Bond; Chiranjeev Dash; Francis M Giardiello; Seth Glick; David Johnson; C Daniel Johnson; Theodore R Levin; Perry J Pickhardt; Douglas K Rex; Robert A Smith; Alan Thorson; Sidney J Winawer Journal: Gastroenterology Date: 2008-02-08 Impact factor: 22.682
Authors: Bergein F Overholt; Linda Brooks-Belli; Michael Grace; Kristin Rankin; Royce Harrell; Mary Turyk; Fred B Rosenberg; Robert W Barish; Norman H Gilinsky Journal: J Clin Gastroenterol Date: 2010-04 Impact factor: 3.062
Authors: Madhusudhan R Sanaka; Fnu Deepinder; Prashanthi N Thota; Rocio Lopez; Carol A Burke Journal: Am J Gastroenterol Date: 2009-06-02 Impact factor: 10.864
Authors: S J Winawer; A G Zauber; M N Ho; M J O'Brien; L S Gottlieb; S S Sternberg; J D Waye; M Schapiro; J H Bond; J F Panish Journal: N Engl J Med Date: 1993-12-30 Impact factor: 91.245
Authors: Muhammad Aziz; Simcha Weissman; Rawish Fatima; Zubair Khan; Babu P Mohan; Tej I Mehta; Wade Lee-Smith; Ammar Hassan; Michael Sciarra; Ali Nawras; Douglas G Adler Journal: Endosc Int Open Date: 2020-05-25
Authors: Colin J Rees; Roisin Bevan; Katharina Zimmermann-Fraedrich; Matthew D Rutter; Douglas Rex; Evelien Dekker; Thierry Ponchon; Michael Bretthauer; Jaroslaw Regula; Brian Saunders; Cesare Hassan; Michael J Bourke; Thomas Rösch Journal: Gut Date: 2016-10-08 Impact factor: 23.059
Authors: Selvi Thirumurthi; Gottumukkala S Raju; Mala Pande; Joseph Ruiz; Richard Carlson; Katherine B Hagan; Jeffrey H Lee; William A Ross Journal: World J Gastrointest Endosc Date: 2017-04-16
Authors: Richard A Helmers; James A Dilling; Christopher R Chaffee; Mark V Larson; Bradly J Narr; Derek A Haas; Robert S Kaplan Journal: Mayo Clin Proc Innov Qual Outcomes Date: 2017-12-01