OBJECTIVE: Disease-modifying antirheumatic drugs (DMARDs) are recommended for virtually all patients with rheumatoid arthritis (RA). We investigated the use of DMARDs in patients with RA in a nationally representative sample of visits to US physicians in the National Ambulatory Care Medical Survey (NAMCS). METHODS: We analyzed the NAMCS visit data from 1996 through 2007 if the physician noted a diagnosis of RA. DMARD utilization was based on the medications listed by the physician. We used generalized linear models to examine the adjusted associations between DMARD use and potential predictors. RESULTS: Of the 859 visits with a diagnosis code of RA identified over the study period, 404 visits (47%; 95% confidence interval [95% CI] 44-50%) had an associated DMARD. The percentage of RA visits with DMARDs increased slightly over the 12 years (P = 0.048), with biologic DMARDs increasing to 20% of visits after their introduction (P for trend <0.001). In fully adjusted models, African American race was associated with a 30% reduction in DMARD prescribing (risk ratio [RR] 0.70, 95% CI 0.48-1.00). A visit to a rheumatologist was the strongest correlate of DMARD prescribing (RR 2.33, 95% CI 1.89-2.86). Among visits to nonrheumatologists, African Americans were significantly less likely than whites to receive a DMARD (RR 0.39, 95% CI 0.17-0.92), but not among visits with rheumatologists (RR 0.81, 95% CI 0.52-1.27). CONCLUSION: In the NAMCS, most visits coded with RA did not have an associated DMARD prescription. African Americans were less likely to receive DMARDs than whites, particularly when visiting nonrheumatologists.
OBJECTIVE: Disease-modifying antirheumatic drugs (DMARDs) are recommended for virtually all patients with rheumatoid arthritis (RA). We investigated the use of DMARDs in patients with RA in a nationally representative sample of visits to US physicians in the National Ambulatory Care Medical Survey (NAMCS). METHODS: We analyzed the NAMCS visit data from 1996 through 2007 if the physician noted a diagnosis of RA. DMARD utilization was based on the medications listed by the physician. We used generalized linear models to examine the adjusted associations between DMARD use and potential predictors. RESULTS: Of the 859 visits with a diagnosis code of RA identified over the study period, 404 visits (47%; 95% confidence interval [95% CI] 44-50%) had an associated DMARD. The percentage of RA visits with DMARDs increased slightly over the 12 years (P = 0.048), with biologic DMARDs increasing to 20% of visits after their introduction (P for trend <0.001). In fully adjusted models, African American race was associated with a 30% reduction in DMARD prescribing (risk ratio [RR] 0.70, 95% CI 0.48-1.00). A visit to a rheumatologist was the strongest correlate of DMARD prescribing (RR 2.33, 95% CI 1.89-2.86). Among visits to nonrheumatologists, African Americans were significantly less likely than whites to receive a DMARD (RR 0.39, 95% CI 0.17-0.92), but not among visits with rheumatologists (RR 0.81, 95% CI 0.52-1.27). CONCLUSION: In the NAMCS, most visits coded with RA did not have an associated DMARD prescription. African Americans were less likely to receive DMARDs than whites, particularly when visiting nonrheumatologists.
Authors: Allan Gibofsky; William R Palmer; John A Goldman; Richard L Lautzenheiser; Joseph A Markenson; Arthur Weaver; Michael H Schiff; Edward C Keystone; Harold E Paulus; Melanie J Harrison; James B Whitmore; Jonathan A Leff Journal: Curr Med Res Opin Date: 2006-01 Impact factor: 2.580
Authors: Gabriela Schmajuk; Amal N Trivedi; Daniel H Solomon; Edward Yelin; Laura Trupin; Eliza F Chakravarty; Jinoos Yazdany Journal: JAMA Date: 2011-02-02 Impact factor: 56.272
Authors: B L Kasiske; J F Neylan; R R Riggio; G M Danovitch; L Kahana; S R Alexander; M G White Journal: N Engl J Med Date: 1991-01-31 Impact factor: 91.245
Authors: Robert B M Landewé; Maarten Boers; Arco C Verhoeven; Rene Westhovens; Mart A F J van de Laar; Harry M Markusse; J Christiaan van Denderen; Marie Louise Westedt; Andre J Peeters; Ben A C Dijkmans; Piet Jacobs; Annelies Boonen; Désirée M F M van der Heijde; Sjef van der Linden Journal: Arthritis Rheum Date: 2002-02
Authors: Nizar N Mahomed; Jane Barrett; Jeffrey N Katz; John A Baron; John Wright; Elena Losina Journal: J Bone Joint Surg Am Date: 2005-06 Impact factor: 5.284
Authors: C J Edwards; N K Arden; D Fisher; J C Saperia; I Reading; T P Van Staa; C Cooper Journal: Rheumatology (Oxford) Date: 2005-07-19 Impact factor: 7.580
Authors: Christine G Parks; Armando Meyer; Laura E Beane Freeman; Jonathan N Hofmann; Dale P Sandler Journal: Occup Environ Med Date: 2019-02-13 Impact factor: 4.402
Authors: Edward Yelin; Chris Tonner; Seoyoung C Kim; Jeffrey N Katz; John Z Ayanian; M Alan Brookhart; Daniel H Solomon Journal: Arthritis Care Res (Hoboken) Date: 2014-07 Impact factor: 4.794
Authors: Candace H Feldman; LeRoi S Hicks; Tabatha L Norton; Elmer Freeman; Daniel H Solomon Journal: J Clin Rheumatol Date: 2013-10 Impact factor: 3.517
Authors: Brian Walitt; Rachel Mackey; Lewis Kuller; Kevin D Deane; William Robinson; V Michael Holers; Yue-Fang Chang; Larry Moreland Journal: Am J Epidemiol Date: 2013-03-13 Impact factor: 4.897
Authors: Iris Navarro-Millán; Mangala Rajan; Geyanne E Lui; Lisa M Kern; Laura C Pinheiro; Monika M Safford; Sebastian E Sattui; Jeffrey R Curtis Journal: Semin Arthritis Rheum Date: 2020-07-23 Impact factor: 5.532
Authors: Candace H Feldman; Linda T Hiraki; Jun Liu; Michael A Fischer; Daniel H Solomon; Graciela S Alarcón; Wolfgang C Winkelmayer; Karen H Costenbader Journal: Arthritis Rheum Date: 2013-03
Authors: Jeffrey R Curtis; Fenglong Xie; Lang Chen; Paul Muntner; Carlos G Grijalva; Claire Spettell; Joaquim Fernandes; Raechele M McMahan; John W Baddley; Kenneth G Saag; Timothy Beukelman; Elizabeth Delzell Journal: Arthritis Care Res (Hoboken) Date: 2012-10 Impact factor: 4.794