Literature DB >> 2200681

Stereoselectivity in clinical pharmacokinetics and drug development.

D B Campbell1.   

Abstract

Mesh：

Year:  1990        PMID： 2200681     DOI： 10.1007/BF03190194

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN： 0378-7966            Impact factor:   2.441


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  104 in total

1.  Age-associated stereoselective alterations in hexobarbital metabolism.

Authors:  M H Chandler; S R Scott; R A Blouin
Journal:  Clin Pharmacol Ther       Date:  1988-04       Impact factor: 6.875

2.  Inversion of optical configuration of alpha-methylfluorene-2-acetic acid (cicloprofen) in rats and monkeys.

Authors:  S J Lan; K J Kripalani; A V Dean; P Egli; L T Difazio; E C Schreiber
Journal:  Drug Metab Dispos       Date:  1976 Jul-Aug       Impact factor: 3.922

3.  Toxicological and local anaesthetic effects of optically active isomers of two local anaesthetic compounds.

Authors:  G Aberg
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1972

Review 4.  Importance of drug enantiomers in clinical pharmacology.

Authors:  K Williams; E Lee
Journal:  Drugs       Date:  1985-10       Impact factor: 9.546

Review 5.  Chromatographic separation of enantiomers.

Authors:  K G Feitsma; B F Drenth
Journal:  Pharm Weekbl Sci       Date:  1988-02-19

Review 6.  Stereoselective delivery and actions of beta receptor antagonists.

Authors:  T Walle; J G Webb; E E Bagwell; U K Walle; H B Daniell; T E Gaffney
Journal:  Biochem Pharmacol       Date:  1988-01-01       Impact factor: 5.858

Review 7.  Interrelationships between xenobiotic metabolism and lipid biosynthesis.

Authors:  J Caldwell; M V Marsh
Journal:  Biochem Pharmacol       Date:  1983-06-01       Impact factor: 5.858

8.  Pharmacokinetic implications of stereoselective changes in plasma-protein binding: warfarin/sulfinpyrazone.

Authors:  S Toon; W F Trager
Journal:  J Pharm Sci       Date:  1984-11       Impact factor: 3.534

9.  Serum binding of tocainide and its enantiomers in human subjects.

Authors:  A J Sedman; D C Bloedow; J Gal
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1982-10

10.  Stereoselectivity in the metabolism of disopyramide enantiomers in rat and dog.

Authors:  C S Cook; A Karim; P Sollman
Journal:  Drug Metab Dispos       Date:  1982 Mar-Apr       Impact factor: 3.922
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  13 in total

1.  Chirality and drugs used to treat psychiatric disorders.

Authors:  Glen B Baker; Trevor I Prior; Ronald T Coutts
Journal:  J Psychiatry Neurosci       Date:  2002-11       Impact factor: 6.186

Review 2.  Clinical pharmacology through the looking glass: reflections on the racemate vs enantiomer debate.

Authors:  M S Lennard
Journal:  Br J Clin Pharmacol       Date:  1991-06       Impact factor: 4.335

Review 3.  The use of toxicokinetics for the safety assessment of drugs acting in the brain.

Authors:  D B Campbell
Journal:  Mol Neurobiol       Date:  1995 Aug-Dec       Impact factor: 5.590

Review 4.  Chirality in new drug development. Clinical pharmacokinetic considerations.

Authors:  R L Nation
Journal:  Clin Pharmacokinet       Date:  1994-10       Impact factor: 6.447

Review 5.  Pharmacokinetic-pharmacodynamic relationships in phase I/phase II of drug development.

Authors:  A Van Peer; E Snoeck; M L Huang; J Heykants
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1993 Jan-Mar       Impact factor: 2.441

6.  Effect of the aluminium ion on hepatic elimination of quinine and quinidine.

Authors:  V Jakovljević; M Popović; A Sabo; B Banić
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1995 Jul-Sep       Impact factor: 2.441

Review 7.  Stereoisomers and drug toxicity. The value of single stereoisomer therapy.

Authors:  A K Scott
Journal:  Drug Saf       Date:  1993-02       Impact factor: 5.606

8.  A pharmacokinetic comparison of meloxicam and ketoprofen following oral administration to healthy dogs.

Authors:  L Montoya; L Ambros; V Kreil; R Bonafine; G Albarellos; R Hallu; A Soraci
Journal:  Vet Res Commun       Date:  2004-07       Impact factor: 2.459

Review 9.  Chirality and drugs used in psychiatry: nice to know or need to know?

Authors:  R M Lane; G B Baker
Journal:  Cell Mol Neurobiol       Date:  1999-06       Impact factor: 5.046

Review 10.  The cost benefit ratio of enantiomeric drugs.

Authors:  G Pifferi; E Perucca
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1995 Jan-Mar       Impact factor: 2.441
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