Literature DB >> 7834962

Chirality in new drug development. Clinical pharmacokinetic considerations.

R L Nation1.   

Abstract

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Year:  1994        PMID： 7834962     DOI： 10.2165/00003088-199427040-00001

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN： 0312-5963            Impact factor:   6.447


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  28 in total

1.  Racemates versus enantiomers in drug development: dogmatism or pragmatism?

Authors:  B Testa; W F Trager
Journal:  Chirality       Date:  1990       Impact factor: 2.437

Review 2.  Stereoselectivity in clinical pharmacokinetics and drug development.

Authors:  D B Campbell
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1990 Apr-Jun       Impact factor: 2.441

Review 3.  Chirality and its importance in drug development: what are the issues?

Authors:  A H Beckett
Journal:  Biochem Soc Trans       Date:  1991-04       Impact factor: 5.407

4.  Age-associated stereoselective alterations in hexobarbital metabolism.

Authors:  M H Chandler; S R Scott; R A Blouin
Journal:  Clin Pharmacol Ther       Date:  1988-04       Impact factor: 6.875

5.  Stereoselective drug disposition: potential for misinterpretation of drug disposition data.

Authors:  A M Evans; R L Nation; L N Sansom; F Bochner; A A Somogyi
Journal:  Br J Clin Pharmacol       Date:  1988-12       Impact factor: 4.335

Review 6.  Importance of drug enantiomers in clinical pharmacology.

Authors:  K Williams; E Lee
Journal:  Drugs       Date:  1985-10       Impact factor: 9.546

Review 7.  Bioequivalence requirements for generic products.

Authors:  R L Nation; L N Sansom
Journal:  Pharmacol Ther       Date:  1994 Apr-May       Impact factor: 12.310

8.  Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology.

Authors:  E J Ariëns
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

9.  Stereoselective disposition of ibuprofen enantiomers in man.

Authors:  E J Lee; K Williams; R Day; G Graham; D Champion
Journal:  Br J Clin Pharmacol       Date:  1985-05       Impact factor: 4.335

10.  Effects of d,l-verapamil on atrioventricular conduction in relation to its stereoselective first-pass metabolism.

Authors:  H Echizen; B Vogelgesang; M Eichelbaum
Journal:  Clin Pharmacol Ther       Date:  1985-07       Impact factor: 6.875
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  4 in total

1.  Stereoselective HPLC assay of TJ0711 enantiomers by precolumn derivatization with GITC using UV detection and its application in pharmacokinetics in rats.

Authors:  Shuping Sun; Luqin Si; Zhaoze Fan; Jun Qiu; Gao Li
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2009-08-07

Review 2.  Clinical pharmacokinetics of dexketoprofen.

Authors:  M J Barbanoj; R M Antonijoan; I Gich
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

Review 3.  Chirality and drugs used in psychiatry: nice to know or need to know?

Authors:  R M Lane; G B Baker
Journal:  Cell Mol Neurobiol       Date:  1999-06       Impact factor: 5.046

Review 4.  The cost benefit ratio of enantiomeric drugs.

Authors:  G Pifferi; E Perucca
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1995 Jan-Mar       Impact factor: 2.441
  4 in total

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