Literature DB >> 22006494

Biological mesh reconstruction of perineal wounds following enhanced abdominoperineal excision of rectum (APER).

Oliver Peacock1, H Pandya, T Sharp, N G Hurst, W J Speake, G M Tierney, J N Lund.   

Abstract

INTRODUCTION: An abdominoperineal excision of rectum (APER) may be required for rectal tumours less than 6 cm from the anal verge. Recently, the cylindrical APER has been used to prevent the "surgical waist" and so decrease margin involvement. However, removal of the levators leaves a large defect. Myocutaneous flaps [e.g. vertical rectus abdominis (VRAM)] are often used to fill the cylindrical resection defect, but have disadvantages associated with operative time, expertise and morbidity. We report our early experience of pelvic floor reconstruction with a biological mesh following cylindrical APER.
METHODS: Data on consecutive patients having cylindrical APER between January 2008 and November 2010 were collected. Outcomes were compared between a VRAM reconstruction group and a mesh group.
RESULTS: In 15 consecutive patients with low rectal cancer, five patients had VRAM pelvic floor reconstruction prior to ten patients having biosynthetic mesh repairs. The median operative time for the VRAM cohort was 405 min, compared with 259 min for the mesh (p = 0.0013). The median length of postoperative stay was 20 days for VRAM and 10 days for the mesh group (p = 0.067). There were four early complications for the VRAM group compared with seven for the mesh cohort (p = 0.37). The median cost per patient for the VRAM cohort was £11,075 compared to a median cost of £6,513 for the Mesh (p = 0.0097).
CONCLUSION: The use of a biological mesh for pelvic floor reconstruction following cylindrical APER is feasible with morbidity comparable to VRAM reconstruction. There is significant cost-saving using a biosynthetic mesh, mainly due to reduced length of stay.

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Year:  2011        PMID: 22006494     DOI: 10.1007/s00384-011-1325-2

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  32 in total

1.  Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in The Netherlands.

Authors:  E Kapiteijn; H Putter; C J H van de Velde
Journal:  Br J Surg       Date:  2002-09       Impact factor: 6.939

2.  Primary perineal wound closure after preoperative radiotherapy and abdominoperineal resection has a high incidence of wound failure.

Authors:  Kelli M Bullard; Judith L Trudel; Nancy N Baxter; David A Rothenberger
Journal:  Dis Colon Rectum       Date:  2005-03       Impact factor: 4.585

3.  Local recurrence following total mesorectal excision for rectal cancer.

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Journal:  Br J Surg       Date:  1996-03       Impact factor: 6.939

4.  Abdominoperineal excision of the rectum--an endangered operation. Norman Nigro Lectureship.

Authors:  R J Heald; R K Smedh; A Kald; R Sexton; B J Moran
Journal:  Dis Colon Rectum       Date:  1997-07       Impact factor: 4.585

Review 5.  Abdominoperineal resection for adenocarcinoma of the low rectum.

Authors:  D A Rothenberger; W D Wong
Journal:  World J Surg       Date:  1992 May-Jun       Impact factor: 3.352

6.  Results of salvage abdominoperineal resection for recurrent anal carcinoma following combined chemoradiation therapy.

Authors:  B C van der Wal; B I Cleffken; B Gulec; H S Kaufman; M A Choti
Journal:  J Gastrointest Surg       Date:  2001 Jul-Aug       Impact factor: 3.452

7.  Primary rectus abdominis myocutaneous flap for repair of perineal and vaginal defects after extended abdominoperineal resection.

Authors:  S W Bell; N Dehni; M Chaouat; J C Lifante; R Parc; E Tiret
Journal:  Br J Surg       Date:  2005-04       Impact factor: 6.939

8.  Use of human acellular dermal matrix in complex and contaminated abdominal wall reconstructions.

Authors:  Joe H Patton; Stepheny Berry; Kurt A Kralovich
Journal:  Am J Surg       Date:  2007-03       Impact factor: 2.565

9.  Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997.

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Journal:  Arch Surg       Date:  1998-08

10.  The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?

Authors:  R J Heald; E M Husband; R D Ryall
Journal:  Br J Surg       Date:  1982-10       Impact factor: 6.939

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  23 in total

1.  A hundred patients with vertical rectus abdominis myocutaneous (VRAM) flap for pelvic reconstruction after total pelvic exenteration.

Authors:  R E Horch; W Hohenberger; A Eweida; U Kneser; K Weber; A Arkudas; S Merkel; J Göhl; J P Beier
Journal:  Int J Colorectal Dis       Date:  2014-04-22       Impact factor: 2.571

2.  The management of perineal hernia following abdomino-perineal excision for cancer.

Authors:  K Bertrand; J H Lefevre; B Creavin; M Luong; C Debove; T Voron; N Chafai; E Tiret; Y Parc
Journal:  Hernia       Date:  2019-03-18       Impact factor: 4.739

Review 3.  Perineal reconstruction after extra-levator abdominoperineal excision (eLAPE): a systematic review.

Authors:  Hisham Z Butt; Murtaza K Salem; Badri Vijaynagar; Sanjay Chaudhri; Baljit Singh
Journal:  Int J Colorectal Dis       Date:  2013-02-26       Impact factor: 2.571

4.  Vertical rectus abdominis myocutaneous flap and quality of life following abdominoperineal excision for rectal cancer: a multi-institutional study.

Authors:  V O'Dowd; J P Burke; E Condon; D Waldron; N Ajmal; J Deasy; D A McNamara; J C Coffey
Journal:  Tech Coloproctol       Date:  2014-05-07       Impact factor: 3.781

5.  Outcomes after biological mesh reconstruction of the pelvic floor following extra-levator abdominoperineal excision of rectum (APER).

Authors:  O Peacock; J A Simpson; S I Tou; N G Hurst; W J Speake; G M Tierney; J N Lund
Journal:  Tech Coloproctol       Date:  2014-01-17       Impact factor: 3.781

Review 6.  Management of the Perineal Defect after Abdominoperineal Excision.

Authors:  Colin Peirce; Sean Martin
Journal:  Clin Colon Rectal Surg       Date:  2016-06

7.  Dynamic magnetic resonance imaging evaluation of pelvic reconstruction with porcine dermal collagen mesh following extra-levator abdominoperineal excision for primary rectal cancer.

Authors:  Adam Dinnewitzer; Matthias Meissnitzer; Thomas Meissnitzer; Clemens Nawara; Christoph Augschöll; Selina Buchner; Franz Mayer; Dietmar Öfner
Journal:  Int J Colorectal Dis       Date:  2015-02-21       Impact factor: 2.571

8.  Results of extralevator abdominoperineal resection for low rectal cancer including quality of life and long-term wound complications.

Authors:  Thilo Welsch; Vyron Mategakis; Pietro Contin; Yakup Kulu; Markus W Büchler; Alexis Ulrich
Journal:  Int J Colorectal Dis       Date:  2012-11-21       Impact factor: 2.571

9.  Laparoscopic repair of post-abdominoperineal resection hernia: biological mesh and augmentation technique.

Authors:  E Chelala; S Declercq
Journal:  Hernia       Date:  2013-11-16       Impact factor: 4.739

10.  The painless combination of anatomically contoured titanium plates and porcine dermal collagen patch for chest wall reconstruction.

Authors:  Kingsfield Ong; Chin Siang Ong; Yang Chong Chua; Ali Akbar Fazuludeen; Aneez Dokeu Basheer Ahmed
Journal:  J Thorac Dis       Date:  2018-05       Impact factor: 2.895

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