Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The real cost of sequencing: higher than you think!

Literature DB >> 21867570

The real cost of sequencing: higher than you think!

Andrea Sboner¹, Xinmeng Jasmine Mu, Dov Greenbaum, Raymond K Auerbach, Mark B Gerstein.

Abstract

Advances in sequencing technology have led to a sharp decrease in the cost of 'data generation'. But is this sufficient to ensure cost-effective and efficient 'knowledge generation'?

Entities: CellLine Chemical Disease Gene Species

Mesh：

Year: 2011 PMID： 21867570 PMCID： PMC3245608 DOI： 10.1186/gb-2011-12-8-125

Source DB: PubMed Journal: Genome Biol ISSN： 1474-7596 Impact factor: 13.583

40 in total

Review 1. Toward the 1,000 dollars human genome.

Authors: Simon T Bennett; Colin Barnes; Anthony Cox; Lisa Davies; Clive Brown
Journal: Pharmacogenomics Date: 2005-06 Impact factor: 2.533

2. A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome.

Authors: Marc Sultan; Marcel H Schulz; Hugues Richard; Alon Magen; Andreas Klingenhoff; Matthias Scherf; Martin Seifert; Tatjana Borodina; Aleksey Soldatov; Dmitri Parkhomchuk; Dominic Schmidt; Sean O'Keeffe; Stefan Haas; Martin Vingron; Hans Lehrach; Marie-Laure Yaspo
Journal: Science Date: 2008-07-03 Impact factor: 47.728

3. The case for cloud computing in genome informatics.

Authors: Lincoln D Stein
Journal: Genome Biol Date: 2010-05-05 Impact factor: 13.583

Review 4. Elucidating the inosinome: global approaches to adenosine-to-inosine RNA editing.

Authors: Bjorn-Erik Wulff; Masayuki Sakurai; Kazuko Nishikura
Journal: Nat Rev Genet Date: 2010-12-21 Impact factor: 53.242

5. Cloud computing and the DNA data race.

Authors: Michael C Schatz; Ben Langmead; Steven L Salzberg
Journal: Nat Biotechnol Date: 2010-07 Impact factor: 54.908

6. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis.

Authors: Thomas A Down; Vardhman K Rakyan; Daniel J Turner; Paul Flicek; Heng Li; Eugene Kulesha; Stefan Gräf; Nathan Johnson; Javier Herrero; Eleni M Tomazou; Natalie P Thorne; Liselotte Bäckdahl; Marlis Herberth; Kevin L Howe; David K Jackson; Marcos M Miretti; John C Marioni; Ewan Birney; Tim J P Hubbard; Richard Durbin; Simon Tavaré; Stephan Beck
Journal: Nat Biotechnol Date: 2008-07 Impact factor: 54.908

7. ArrayExpress update--an archive of microarray and high-throughput sequencing-based functional genomics experiments.

Authors: Helen Parkinson; Ugis Sarkans; Nikolay Kolesnikov; Niran Abeygunawardena; Tony Burdett; Miroslaw Dylag; Ibrahim Emam; Anna Farne; Emma Hastings; Ele Holloway; Natalja Kurbatova; Margus Lukk; James Malone; Roby Mani; Ekaterina Pilicheva; Gabriella Rustici; Anjan Sharma; Eleanor Williams; Tomasz Adamusiak; Marco Brandizi; Nataliya Sklyar; Alvis Brazma
Journal: Nucleic Acids Res Date: 2010-11-10 Impact factor: 16.971

8. Ongoing and future developments at the Universal Protein Resource.

Authors:
Journal: Nucleic Acids Res Date: 2010-11-04 Impact factor: 16.971

9. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences.

Authors: Jeremy Goecks; Anton Nekrutenko; James Taylor
Journal: Genome Biol Date: 2010-08-25 Impact factor: 13.583

10. Searching for SNPs with cloud computing.

Authors: Ben Langmead; Michael C Schatz; Jimmy Lin; Mihai Pop; Steven L Salzberg
Journal: Genome Biol Date: 2009-11-20 Impact factor: 13.583

126 in total

1. On the future of genetic risk assessment.

Authors: Hans-Hilger Ropers
Journal: J Community Genet Date: 2012-04-01

Review 2. The long tail and rare disease research: the impact of next-generation sequencing for rare Mendelian disorders.

Authors: Tony Shen; Ariel Lee; Carol Shen; C Jimmy Lin
Journal: Genet Res (Camb) Date: 2015-09-14 Impact factor: 1.588

The real cost of sequencing: higher than you think!

Review 1. Toward the 1,000 dollars human genome.

2. A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome.

3. The case for cloud computing in genome informatics.

Review 4. Elucidating the inosinome: global approaches to adenosine-to-inosine RNA editing.

5. Cloud computing and the DNA data race.

6. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis.

7. ArrayExpress update--an archive of microarray and high-throughput sequencing-based functional genomics experiments.

8. Ongoing and future developments at the Universal Protein Resource.

9. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences.

10. Searching for SNPs with cloud computing.

1. On the future of genetic risk assessment.

Review 2. The long tail and rare disease research: the impact of next-generation sequencing for rare Mendelian disorders.

3. Challenges of using next generation sequencing in newborn screening.

4. RAD Capture (Rapture): Flexible and Efficient Sequence-Based Genotyping.

5. Quantification of private information leakage from phenotype-genotype data: linking attacks.

6. Biological intuition in alignment-free methods: response to Posada.

Review 7. The role of replicates for error mitigation in next-generation sequencing.

8. ESPRIT-Forest: Parallel clustering of massive amplicon sequence data in subquadratic time.

9. Development of SSR markers by next-generation sequencing of Korean landraces of chamoe (Cucumis melo var. makuwa).

Review 10. Evolving approaches to the ethical management of genomic data.