Literature DB >> 21857756

Azomethine ylide mediated inversion of configuration of quaternary imidazoline carbon: converting trans- to its cis- imidazolines.

Ke Qu1, Jason S Fisk, Jetze J Tepe.   

Abstract

An efficient synthetic methodology of converting trans-4,5-diaryl-2-imidazolines to the corresponding cis-4,5-diaryl-2-imidazolines has been developed. This methodology features mild reaction conditions and a simple one-pot two-step procedure.

Entities:  

Year:  2011        PMID： 21857756      PMCID： PMC3157035          DOI： 10.1016/j.tetlet.2011.07.022

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  12 in total

1.  Highly diastereoselective multicomponent synthesis of unsymmetrical imidazolines.

Authors:  Satymaheshwar Peddibhotla; S Jayakumar; Jetze J Tepe
Journal:  Org Lett       Date:  2002-10-03       Impact factor: 6.005

2.  Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines.

Authors:  Vasudha Sharma; Theresa A Lansdell; Satyamaheshwar Peddibhotla; Jetze J Tepe
Journal:  Chem Biol       Date:  2004-12

Review 3.  The diverse chemistry of oxazol-5-(4H)-ones.

Authors:  Jason S Fisk; Robert A Mosey; Jetze J Tepe
Journal:  Chem Soc Rev       Date:  2007-03-12       Impact factor: 54.564

4.  Sensitization of cancer cells to DNA damaging agents by imidazolines.

Authors:  Vasudha Sharma; Satyamaheshwar Peddibhotla; Jetze J Tepe
Journal:  J Am Chem Soc       Date:  2006-07-19       Impact factor: 15.419

5.  Multicomponent synthesis of 2-imidazolines.

Authors:  Robin S Bon; Bart van Vliet; Nanda E Sprenkels; Rob F Schmitz; Frans J J de Kanter; Christian V Stevens; Marcel Swart; F Matthias Bickelhaupt; Marinus B Groen; Romano V A Orru
Journal:  J Org Chem       Date:  2005-04-29       Impact factor: 4.354

6.  A novel general route for the preparation of enantiopure imidazolines.

Authors:  Nicola A Boland; Mike Casey; Stephen J Hynes; Jonathan W Matthews; Martin P Smyth
Journal:  J Org Chem       Date:  2002-05-31       Impact factor: 4.354

7.  Preparation of enantiopure biimidazoline ligands and their use in asymmetric catalysis.

Authors:  Nicola A Boland; Mike Casey; Stephen J Hynes; Jonathan W Matthews; Helge Muller-Bunz; Philippa Wilkes
Journal:  Org Biomol Chem       Date:  2004-06-28       Impact factor: 3.876

8.  Novel imidazolination reaction of alkenes provides an easy access to new alpha,beta-differentiated 1,2-vicinal diamines.

Authors:  Wei Pei; Cody Timmons; Xin Xu; Han-Xun Wei; Guigen Li
Journal:  Org Biomol Chem       Date:  2003-08-21       Impact factor: 3.876

9.  In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.

Authors:  Lyubomir T Vassilev; Binh T Vu; Bradford Graves; Daisy Carvajal; Frank Podlaski; Zoran Filipovic; Norman Kong; Ursula Kammlott; Christine Lukacs; Christian Klein; Nader Fotouhi; Emily A Liu
Journal:  Science       Date:  2004-01-02       Impact factor: 47.728

10.  Synthesis of enantiopure imidazolines through a Ritter reaction of 2-(1-aminoalkyl)aziridines with nitriles.

Authors:  José M Concellón; Estela Riego; José Ramón Suárez; Santiago García-Granda; M Rosario Díaz
Journal:  Org Lett       Date:  2004-11-25       Impact factor: 6.005
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  1 in total

1.  Palladium-catalyzed multicomponent synthesis of 2-imidazolines from imines and acid chlorides.

Authors:  Boran Xu; Kraig Worrall; Bruce A Arndtsen
Journal:  Molecules       Date:  2012-11-22       Impact factor: 4.411
  1 in total

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