| Literature DB >> 15548060 |
José M Concellón1, Estela Riego, José Ramón Suárez, Santiago García-Granda, M Rosario Díaz.
Abstract
The Ritter reaction of enantiopure 2-(1-aminoalkyl)aziridines 1 with different nitriles afford enantiopure tetrasubstituted imidazolines 2. The opening of the aziridine ring takes place with total regio- and stereoselectivity. A mechanism to explain the described addition reaction is proposed. [reaction: see text]Entities:
Year: 2004 PMID： 15548060 DOI： 10.1021/ol048176j
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005