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Literature DB >> 21812076

Introducing lasso peptides as molecular scaffolds for drug design: engineering of an integrin antagonist.

Thomas A Knappe¹, Florian Manzenrieder, Carlos Mas-Moruno, Uwe Linne, Florenz Sasse, Horst Kessler, Xiulan Xie, Mohamed A Marahiel.

Abstract

Mesh：

Substances：
Integrins
Peptides

Year: 2011 PMID： 21812076 DOI： 10.1002/anie.201102190

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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Cited

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25 in total

1. Facile Removal of Leader Peptides from Lanthipeptides by Incorporation of a Hydroxy Acid.

Authors: Noah A Bindman; Silvia C Bobeica; Wenshe R Liu; Wilfred A van der Donk
Journal: J Am Chem Soc Date: 2015-06-01 Impact factor: 15.419

2. Evidence of Cis/Trans-Isomerization at Pro7/Pro16 in the Lasso Peptide Microcin J25.

Authors: Kevin Jeanne Dit Fouque; Julian D Hegemann; Séverine Zirah; Sylvie Rebuffat; Ewen Lescop; Francisco Fernandez-Lima
Journal: J Am Soc Mass Spectrom Date: 2019-03-04 Impact factor: 3.109

3. Signatures of Mechanically Interlocked Topology of Lasso Peptides by Ion Mobility-Mass Spectrometry: Lessons from a Collection of Representatives.

Authors: Kevin Jeanne Dit Fouque; Hélène Lavanant; Séverine Zirah; Julian D Hegemann; Marcel Zimmermann; Mohamed A Marahiel; Sylvie Rebuffat; Carlos Afonso
Journal: J Am Soc Mass Spectrom Date: 2016-11-03 Impact factor: 3.109

4. Multispecies activity screening of microcin J25 mutants yields antimicrobials with increased specificity toward pathogenic Salmonella species relative to human commensal Escherichia coli.

Authors: Seth C Ritter; Mike L Yang; Yiannis N Kaznessis; Benjamin J Hackel
Journal: Biotechnol Bioeng Date: 2018-07-20 Impact factor: 4.530

Introducing lasso peptides as molecular scaffolds for drug design: engineering of an integrin antagonist.

1. Facile Removal of Leader Peptides from Lanthipeptides by Incorporation of a Hydroxy Acid.

2. Evidence of Cis/Trans-Isomerization at Pro7/Pro16 in the Lasso Peptide Microcin J25.

3. Signatures of Mechanically Interlocked Topology of Lasso Peptides by Ion Mobility-Mass Spectrometry: Lessons from a Collection of Representatives.

4. Multispecies activity screening of microcin J25 mutants yields antimicrobials with increased specificity toward pathogenic Salmonella species relative to human commensal Escherichia coli.

Review 5. How to harness biosynthetic gene clusters of lasso peptides.

6. Expanding the chemical diversity of lasso peptide MccJ25 with genetically encoded noncanonical amino acids.

7. Ribosomal route to small-molecule diversity.

8. Characterization of Leader Peptide Binding During Catalysis by the Nisin Dehydratase NisB.

9. Generation of thiocillin ring size variants by prepeptide gene replacement and in vivo processing by Bacillus cereus.

Review 10. Biosynthetic Proteases That Catalyze the Macrocyclization of Ribosomally Synthesized Linear Peptides.