| Literature DB >> 2174817 |
V S Kitchen1, M Helbert, N D Francis, R P Logan, F A Lewis, A W Boylston, A J Pinching, J R Harris.
Abstract
Epstein-Barr virus (EBV) associated ulceration has not previously been included in the differential diagnosis of oesophageal ulcers in AIDS. We report five cases of oesophageal ulceration in homosexual men with advanced human immunodeficiency virus infection in whom this was considered to be the most likely cause. DNA in situ hybridisation studies showed EBV in biopsy material from three of four patients with oesophageal ulcers and in none of three controls. Of other viruses studied, only human papillomavirus was present, and this was found in both patients and control subjects. These findings support the hypothesis that EBV is an aetiological factor in some cases of AIDS-associated oesophageal ulceration.Entities:
Mesh:
Year: 1990 PMID: 2174817 PMCID: PMC1378688 DOI: 10.1136/gut.31.11.1223
Source DB: PubMed Journal: Gut ISSN: 0017-5749 Impact factor: 23.059