Literature DB >> 21742307

Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue.

Raneen Shehadeh-Mashor1, Sathish Srinivasan, Corey Boimer, Kenneth Lee, Oren Tomkins, Allan R Slomovic.   

Abstract

PURPOSE: To evaluate the safety and efficacy of using fibrin glue in cases of recurrent pterygium treated with pterygium excision and conjunctival autograft combined with mitomycin C.
DESIGN: Retrospective, interventional case series.
METHODS: The charts of 28 patients with recurrent pterygium who had undergone pterygium excision and conjunctival autograft using fibrin glue to secure the graft combined with intraoperative mitomycin C at a corneal service in a university teaching hospital were reviewed. Inclusion criteria were recurrent pterygium that had undergone at least 1 previous surgical excision and patients who had completed a regular postoperative follow-up of at least 12 months. Outcome measures included mean best-corrected visual acuity (BCVA) and intraoperative and postoperative complications.
RESULTS: The mean age of the cohort was 49.7 years. There were no intraoperative complications. Early postoperative total graft dehiscence developed in 1 eye that underwent repositioning with glue and sutures. One eye had mild graft dehiscence and required no surgical intervention. One eye had a conjunctival cyst on the graft that did not require intervention. No significant change was observed in BCVA. At a mean follow-up of 26.5 months, there was 1 case of recurrence.
CONCLUSIONS: Pterygium excision and conjunctival autograft using fibrin glue to secure the graft combined with intraoperative mitomycin C seems to be a safe and effective surgical option for treating recurrent pterygium. However, a larger cohort with longer follow-up may be required to assess the recurrence rate of this method.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21742307     DOI: 10.1016/j.ajo.2011.04.034

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  9 in total

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Authors:  Chunyan Xue; Yueqin Chen; Zhenping Huang; Yirui Ge; Haiyan Wang; Jiandong Wang
Journal:  Int J Clin Exp Med       Date:  2014-11-15

2.  Relationship between angiogenesis and lymphangiogenesis in recurrent pterygium.

Authors:  Chao-Xiu Qi; Xiao-Dong Zhang; Jin Yuan; Jie-Zhen Yang; Yi Sun; Tao Wang; Hui Ye; Shi-Qi Ling
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Review 3.  Developments and current approaches in the treatment of pterygium.

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Journal:  Int Ophthalmol       Date:  2016-09-23       Impact factor: 2.031

4.  Fifteen-year results of a randomized controlled trial comparing 0.02% mitomycin C, limbal conjunctival autograft, and combined mitomycin C with limbal conjunctival autograft in recurrent pterygium surgery.

Authors:  Ka Wai Kam; Alvin L Young
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2019-10-24       Impact factor: 3.117

5.  Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow-up.

Authors:  Waleed Alsarhani; Saeed Alshahrani; Mahmood Showail; Nawaf Alhabdan; Osama Alsumari; Abdullah Almalki; Abdulaziz Alsarhani; Adel Alluhaidan; Bader Alqahtani
Journal:  BMC Ophthalmol       Date:  2021-05-11       Impact factor: 2.209

6.  Evaluation of Conjunctival Autografting Augmented with Mitomycin C Application versus Ologen Implantation in the Surgical Treatment of Recurrent Pterygium.

Authors:  Faried M Wagdy; Hassan G Farahat; Amin F Ellakwa; Sameh S Mandour
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Review 7.  Recurrent Pterygium: A Review.

Authors:  Leila Ghiasian; Bijan Samavat; Yasaman Hadi; Mona Arbab; Navid Abolfathzadeh
Journal:  J Curr Ophthalmol       Date:  2022-01-06

8.  Pre- and intraoperative mitomycin C for recurrent pterygium associated with symblepharon.

Authors:  Isyaku Mohammed
Journal:  Clin Ophthalmol       Date:  2013-01-23

Review 9.  Targeting the integrated stress response in ophthalmology.

Authors:  Hsiao-Sang Chu; Cornelia Peterson; Albert Jun; James Foster
Journal:  Curr Eye Res       Date:  2021-01-21       Impact factor: 2.555

  9 in total

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