Literature DB >> 31650270

Fifteen-year results of a randomized controlled trial comparing 0.02% mitomycin C, limbal conjunctival autograft, and combined mitomycin C with limbal conjunctival autograft in recurrent pterygium surgery.

Ka Wai Kam1,2, Alvin L Young3,4.   

Abstract

PURPOSE: To compare the long-term outcomes of recurrent pterygium surgery between three different techniques.
METHODS: We performed a 15-year follow-up study of a randomized controlled study on surgical management of recurrent pterygium. Group 1 received limbal conjunctival autograft (LCAU); group 2 received intraoperative mitomycin C (MMC) 0.02% for 5 min; and group 3 received combined LCAU + MMC 0.02% for 5 min. Consecutive patients enrolled in the original study (from April 2001 to March 2003) were invited back for a detailed clinical examination to document the long-term outcomes. The main outcome measures included the recurrence rate, residual conjunctival bed status, and complications from any of the surgical methods.
RESULTS: Sixty-two patients were recruited in the original study. Eight patients had passed away and 12 patients were uncontactable or not responded. One patient who had bilateral operations refused to return for follow-up and one eye had insufficient data for analysis. Finally, 40 eyes of 40 patients were included for analyses. One eye developed a recurrence over 15 years and none required a tertiary pterygium operation. The patient received LCAU for a temporal recurrent pterygium developed a 2.2-mm recurrence.
CONCLUSIONS: All three techniques yielded favorable outcomes for patients with recurrent pterygium. The use of LCAU was associated with better cosmetic outcome.

Entities:  

Keywords:  Cornea; Limbal conjunctival autograft; Mitomycin C; Randomized controlled trial; Recurrent pterygium

Year:  2019        PMID: 31650270     DOI: 10.1007/s00417-019-04499-5

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  27 in total

1.  Conjunctival-limbal autografts for primary and recurrent pterygia: technique and results.

Authors:  S K Rao; T Lekha; B N Mukesh; G Sitalakshmi; P Padmanabhan
Journal:  Indian J Ophthalmol       Date:  1998-12       Impact factor: 1.848

2.  Pterygium excision and conjunctival mini-autograft.

Authors:  A L Young; J C C Yeung; A T S Leung; A K K Wong; L L Cheng; D S C Lam
Journal:  Eye (Lond)       Date:  2002-01       Impact factor: 3.775

3.  Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue.

Authors:  Raneen Shehadeh-Mashor; Sathish Srinivasan; Corey Boimer; Kenneth Lee; Oren Tomkins; Allan R Slomovic
Journal:  Am J Ophthalmol       Date:  2011-07-13       Impact factor: 5.258

4.  Long term results of intraoperative mitomycin C in the treatment of recurrent pterygium.

Authors:  L Mastropasqua; P Carpineto; M Ciancaglini; P Enrico Gallenga
Journal:  Br J Ophthalmol       Date:  1996-04       Impact factor: 4.638

Review 5.  Conjunctival Autograft Versus Amniotic Membrane Transplantation for Treatment of Pterygium: Findings From a Cochrane Systematic Review.

Authors:  Elizabeth Clearfield; Barbara S Hawkins; Irene C Kuo
Journal:  Am J Ophthalmol       Date:  2017-07-19       Impact factor: 5.258

6.  Young patient's age determines pterygium recurrence after surgery.

Authors:  P Anguria; S Ntuli; T Carmichael
Journal:  Afr Health Sci       Date:  2014-03       Impact factor: 0.927

7.  Comparison of conjunctival autografts, amniotic membrane grafts, and primary closure for pterygium excision.

Authors:  P Prabhasawat; K Barton; G Burkett; S C Tseng
Journal:  Ophthalmology       Date:  1997-06       Impact factor: 12.079

8.  Randomised controlled study of conjunctival autograft versus amniotic membrane graft in pterygium excision.

Authors:  P Luanratanakorn; T Ratanapakorn; O Suwan-Apichon; R S Chuck
Journal:  Br J Ophthalmol       Date:  2006-07-12       Impact factor: 4.638

9.  A Prospective Study of Pterygium Excision and Conjunctival Autograft With Human Fibrin Tissue Adhesive: Effects on Vision, Refraction, and Corneal Topography.

Authors:  Stuti Misra; Jennifer P Craig; Charles N J McGhee; Dipika V Patel
Journal:  Asia Pac J Ophthalmol (Phila)       Date:  2014 Jul-Aug

10.  Tectonic corneal lamellar grafting for severe scleral melting after pterygium surgery.

Authors:  Seng-Ei Ti; Donald T H Tan
Journal:  Ophthalmology       Date:  2003-06       Impact factor: 12.079

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  3 in total

1.  Bibliometric analysis and mapping knowledge domain of pterygium: 2000-2019.

Authors:  Yu-Chi Wang; Fang-Kun Zhao; Qian Liu; Zi-Yan Yu; Jing Wang; Jin-Song Zhang
Journal:  Int J Ophthalmol       Date:  2021-06-18       Impact factor: 1.779

2.  The effect of limbal autograft location at primary pterygium excision on anterior and posterior corneal astigmatism: a comparative prospective study.

Authors:  Burcu Kazanci; Fatma Çorak Eroğlu; Emine Şen
Journal:  Int Ophthalmol       Date:  2022-01-23       Impact factor: 2.029

3.  Recurrence Rate and Clinical Outcome of Amniotic Membrane Transplantation Combined with Mitomycin C in Pterygium Surgery: Two-Year Follow-Up.

Authors:  Hasan Razmjoo; Seyed-Abolfazl Kashfi; Majid Mirmohammadkhani; Mohsen Pourazizi
Journal:  J Res Pharm Pract       Date:  2020-03-28
  3 in total

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