Literature DB >> 27664148

Developments and current approaches in the treatment of pterygium.

Dilek Hacıoğlu1, Hidayet Erdöl2.   

Abstract

PURPOSE: To assess and compare the studies conducted in the literature with recurrence rates and the summary of the justified treatment approaches be presented.
METHOD: Pterygium, a fibrovascular tissue that proceeds from the bulbar conjunctiva towards the cornea, is quite a commonly seen ocular surface deterioration. The treatment is performed through a surgical excision, and the frequent recurrence of this disorder, despite the developments of today, is the major problem experienced in the wake of the surgery. There are various treatment methods applied for the prevention of recurrence; yet, there is no definite view as to what treatment is the most effective one. Since the recurrent pterygium cases are more aggressive than the primary pterygium, it is of great importance to determine the treatment method in which recurrence rate is the lowest. In different studies seen in the literature, there is difficulty in comparing the results due to the fact that the follow-up periods, recurrence criteria and the doses and durations of the medications administered differ from one another.
CONCLUSION: When the literature is reviewed, the bare sclera technique is not used due to the high rate of recurrence, whereas successful results can be achieved through the conjunctival autograft technique. Lower recurrence rates have been reported along with the administration of mitomycin C, 5-FU and other agents that were used as an adjuvant treatment.

Entities:  

Keywords:  Antineoplastics; Pterygium; Radiotherapy; Surgery; Treatment

Mesh:

Substances:

Year:  2016        PMID: 27664148     DOI: 10.1007/s10792-016-0358-5

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  93 in total

Review 1.  The treatment of pterygium.

Authors:  Lawrence W Hirst
Journal:  Surv Ophthalmol       Date:  2003 Mar-Apr       Impact factor: 6.048

2.  Pterygium surgery: fibrin glue versus Vicryl sutures for conjunctival closure.

Authors:  Irit Bahar; Dov Weinberger; Gaton Dan; Rahamim Avisar
Journal:  Cornea       Date:  2006-12       Impact factor: 2.651

Review 3.  Treatment of pterygium.

Authors:  Isyaku Mohammed
Journal:  Ann Afr Med       Date:  2011 Jul-Sep

Review 4.  Options and adjuvants in surgery for pterygium: a report by the American Academy of Ophthalmology.

Authors:  Stephen C Kaufman; Deborah S Jacobs; W Barry Lee; Sophie X Deng; Mark I Rosenblatt; Roni M Shtein
Journal:  Ophthalmology       Date:  2012-10-11       Impact factor: 12.079

5.  A randomized trial of conjunctival autografting for pterygium in the tropics.

Authors:  S Lewallen
Journal:  Ophthalmology       Date:  1989-11       Impact factor: 12.079

6.  Pterygium treatment using 5-FU as adjuvant treatment compared to conjunctiva autograft.

Authors:  C O Bekibele; A M Baiyeroju; B A Olusanya; A O Ashaye; T S Oluleye
Journal:  Eye (Lond)       Date:  2006-06-16       Impact factor: 3.775

7.  Increased numbers of mast cells in pterygia.

Authors:  S I Butrus; M F Ashraf; D M Laby; A I Rabinowitz; S O Tabbara; A A Hidayat
Journal:  Am J Ophthalmol       Date:  1995-02       Impact factor: 5.258

8.  [Thiotepa eyedrops for prevention of pterygium recurrence: 18 years of use].

Authors:  A Tassy; D Ribe
Journal:  J Fr Ophtalmol       Date:  1999-03       Impact factor: 0.818

9.  Conjunctival autografting combined with low-dose mitomycin C for prevention of primary pterygium recurrence.

Authors:  Joseph Frucht-Pery; Frederic Raiskup; Michael Ilsar; David Landau; Faik Orucov; Abraham Solomon
Journal:  Am J Ophthalmol       Date:  2006-03-20       Impact factor: 5.258

10.  Topical application of bevacizumab as an adjunct to recurrent pterygium surgery.

Authors:  Engin B Ozgurhan; Alper Agca; Necip Kara; Kemal Yuksel; Ali Demircan; Ahmet Demirok
Journal:  Cornea       Date:  2013-06       Impact factor: 2.651

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  13 in total

1.  Suppression of fibrosis in human pterygium fibroblasts by butyrate and phenylbutyrate.

Authors:  Yuka Koga; Noriaki Maeshige; Hiroto Tabuchi; Mikiko Uemura; Michiko Aoyama-Ishikawa; Makoto Miyoshi; Chikako Katakami; Makoto Usami
Journal:  Int J Ophthalmol       Date:  2017-09-18       Impact factor: 1.779

2.  Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of Pterygia.

Authors:  Qianli Meng; Yaowu Qin; Monika Deshpande; Fabiana Kashiwabuchi; Murilo Rodrigues; Qiaozhi Lu; Hui Ren; Jennifer H Elisseeff; Gregg L Semenza; Silvia V Montaner; Akrit Sodhi
Journal:  Invest Ophthalmol Vis Sci       Date:  2017-09-01       Impact factor: 4.799

3.  Interferon Alpha-2b Eye Drops Prevent Recurrence of Pterygium After the Bare Sclera Technique: A Single-Center, Sequential, and Controlled Study.

Authors:  Mingyang Yin; Hang Li; Yingnan Zhang; Honglei Dai; Fei Luo; Zhiqiang Pan
Journal:  Cornea       Date:  2019-10       Impact factor: 2.651

4.  Recurrence of Pterygium after Pterygium Excision with Stem Cell Graft and Amniotic Membrane Graft: A Comparison.

Authors:  Syed Ahmer Hussain; Kamran Haider Shaheen; Muhammad Saad Ullah; Aamir Furqan
Journal:  Cureus       Date:  2020-01-01

5.  Identification of Functional Genes in Pterygium Based on Bioinformatics Analysis.

Authors:  Yuting Xu; Chen Qiao; Siying He; Chen Lu; Shiqi Dong; Xiying Wu; Ming Yan; Fang Zheng
Journal:  Biomed Res Int       Date:  2020-11-20       Impact factor: 3.411

Review 6.  Recurrent Pterygium: A Review.

Authors:  Leila Ghiasian; Bijan Samavat; Yasaman Hadi; Mona Arbab; Navid Abolfathzadeh
Journal:  J Curr Ophthalmol       Date:  2022-01-06

7.  Efficacy and Safety of Bevacizumab in the Treatment of Pterygium: An Updated Meta-Analysis of Randomized Controlled Trials.

Authors:  Yi Sun; Bowen Zhang; Xiuhua Jia; Shiqi Ling; Juan Deng
Journal:  J Ophthalmol       Date:  2018-09-05       Impact factor: 1.909

8.  Simple limbal epithelial transplantation for recurrent pterygium: A case series.

Authors:  Zale Mednick; Tanguy Boutin; Adi Einan-Lifshitz; Nir Sorkin; Allan Slomovic
Journal:  Am J Ophthalmol Case Rep       Date:  2018-07-26

9.  Recurrence Rate and Clinical Outcome of Amniotic Membrane Transplantation Combined with Mitomycin C in Pterygium Surgery: Two-Year Follow-Up.

Authors:  Hasan Razmjoo; Seyed-Abolfazl Kashfi; Majid Mirmohammadkhani; Mohsen Pourazizi
Journal:  J Res Pharm Pract       Date:  2020-03-28

10.  Association between HPV detection in swab samples and tissue specimens and ophthalmic pterygium recurrence.

Authors:  Aikaterini K Chalkia; Melpomeni Tseliou; Georgios Bontzos; Nikolaos G Tsakalis; Dimitrios A Liakopoulos; Styliani Blazaki; Georgios Sourvinos; Efstathios T Detorakis
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-06-22       Impact factor: 3.117

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