Literature DB >> 21725897

Nuclear Editing of mRNA 3'-UTRs.

Ling-Ling Chen1, Gordon G Carmichael.   

Abstract

Hundreds of human genes express mRNAs that contain inverted repeat sequences within their 3'-UTRs. When expressed, these sequences can be promiscuously edited by ADAR enzymes, leading to the retention of mRNAs in nuclear paraspeckles. Here we discuss how this retention system can be used to regulate gene expression.

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Year:  2012        PMID: 21725897     DOI: 10.1007/82_2011_149

Source DB:  PubMed          Journal:  Curr Top Microbiol Immunol        ISSN: 0070-217X            Impact factor:   4.291


  10 in total

Review 1.  The emerging role of RNA editing in plasticity.

Authors:  Joshua J C Rosenthal
Journal:  J Exp Biol       Date:  2015-06       Impact factor: 3.312

Review 2.  Non-coding RNAs in chromatin folding and nuclear organization.

Authors:  Sergey V Razin; Alexey A Gavrilov
Journal:  Cell Mol Life Sci       Date:  2021-06-11       Impact factor: 9.261

3.  RNA-editing enzymes ADAR1 and ADAR2 coordinately regulate the editing and expression of Ctn RNA.

Authors:  Aparna Anantharaman; Omid Gholamalamdari; Abid Khan; Je-Hyun Yoon; Michael F Jantsch; Jochen C Hartner; Myriam Gorospe; Supriya G Prasanth; Kannanganattu V Prasanth
Journal:  FEBS Lett       Date:  2017-08-30       Impact factor: 4.124

Review 4.  Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases.

Authors:  Elisa Orecchini; Loredana Frassinelli; Silvia Galardi; Silvia Anna Ciafrè; Alessandro Michienzi
Journal:  Chromosome Res       Date:  2018-02-02       Impact factor: 5.239

5.  Site-directed RNA repair of endogenous Mecp2 RNA in neurons.

Authors:  John R Sinnamon; Susan Y Kim; Glen M Corson; Zhen Song; Hiroyuki Nakai; John P Adelman; Gail Mandel
Journal:  Proc Natl Acad Sci U S A       Date:  2017-10-16       Impact factor: 11.205

6.  One hundred million adenosine-to-inosine RNA editing sites: hearing through the noise.

Authors:  Randi J Ulbricht; Ronald B Emeson
Journal:  Bioessays       Date:  2014-05-30       Impact factor: 4.345

Review 7.  A mark of disease: how mRNA modifications shape genetic and acquired pathologies.

Authors:  Eliana Destefanis; Gülben Avşar; Paula Groza; Antonia Romitelli; Serena Torrini; Pınar Pir; Silvestro G Conticello; Francesca Aguilo; Erik Dassi
Journal:  RNA       Date:  2020-12-29       Impact factor: 4.942

8.  Inverted Alu dsRNA structures do not affect localization but can alter translation efficiency of human mRNAs independent of RNA editing.

Authors:  Claire R Capshew; Kristen L Dusenbury; Heather A Hundley
Journal:  Nucleic Acids Res       Date:  2012-06-25       Impact factor: 16.971

9.  ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins.

Authors:  Aparna Anantharaman; Vidisha Tripathi; Abid Khan; Je-Hyun Yoon; Deepak K Singh; Omid Gholamalamdari; Shuomeng Guang; Johan Ohlson; Helene Wahlstedt; Marie Öhman; Michael F Jantsch; Nicholas K Conrad; Jian Ma; Myriam Gorospe; Supriya G Prasanth; Kannanganattu V Prasanth
Journal:  Nucleic Acids Res       Date:  2017-04-20       Impact factor: 16.971

Review 10.  Multi-level regulation of cellular recognition of viral dsRNA.

Authors:  Alys Peisley; Sun Hur
Journal:  Cell Mol Life Sci       Date:  2012-09-09       Impact factor: 9.261

  10 in total

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