| Literature DB >> 21725897 |
Ling-Ling Chen1, Gordon G Carmichael.
Abstract
Hundreds of human genes express mRNAs that contain inverted repeat sequences within their 3'-UTRs. When expressed, these sequences can be promiscuously edited by ADAR enzymes, leading to the retention of mRNAs in nuclear paraspeckles. Here we discuss how this retention system can be used to regulate gene expression.Entities:
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Year: 2012 PMID: 21725897 DOI: 10.1007/82_2011_149
Source DB: PubMed Journal: Curr Top Microbiol Immunol ISSN: 0070-217X Impact factor: 4.291