Literature DB >> 21718162

Peopling the Tibetan plateau: insights from archaeology.

Mark Aldenderfer1.   

Abstract

Recent studies of the genome of modern Tibetans have revealed the existence of genes thought to provide an adaptive advantage for life at high elevation. Extrapolating from this discovery, some researchers now argue that a Tibetan-Han split occurred no more than 2750 yr ago. This date is implausible, and in this paper I review the archaeological data from the Tibetan plateau as one means by which to examine the veracity of this assertion. Following a review of the general state of knowledge of Tibetan prehistory, which is unfortunately only at its beginnings, I first examine the data that speak to the initial peopling of the plateau and assess the evidence that traces of their presence can be seen in modern Tibetans today. Although the data are sparse, both archaeology and genetics suggest that the plateau was occupied in the Late Pleistocene, perhaps as early as 30,000 yr ago, and that these early peoples have left a genetic signature in modern Tibetans. I then turn to the evidence for later migrations and focus on the question of the timing of the establishment of permanent settled villages on the plateau. Three areas of the plateau-northeastern Qinghai, extreme eastern Tibet, and the Yarlung Tsangpo valley-have evidence of permanent settlements dating from ca. 6500, 5900, and 3750 yr ago, respectively. These data are not consonant with the 2750 yr ago date for the split and suggest at a minimum that the plateau has been occupied substantially longer and, further, that multiple migrations at different times and from different places have created a complex mosaic of population history. © Mary Ann Liebert, Inc.

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Year:  2011        PMID: 21718162     DOI: 10.1089/ham.2010.1094

Source DB:  PubMed          Journal:  High Alt Med Biol        ISSN: 1527-0297            Impact factor:   1.981


  46 in total

Review 1.  Genetic determinants of Tibetan high-altitude adaptation.

Authors:  Tatum S Simonson; Donald A McClain; Lynn B Jorde; Josef T Prchal
Journal:  Hum Genet       Date:  2011-11-09       Impact factor: 4.132

Review 2.  Altitude Adaptation: A Glimpse Through Various Lenses.

Authors:  Tatum S Simonson
Journal:  High Alt Med Biol       Date:  2015-06       Impact factor: 1.981

Review 3.  Adaptations to local environments in modern human populations.

Authors:  Choongwon Jeong; Anna Di Rienzo
Journal:  Curr Opin Genet Dev       Date:  2014-08-15       Impact factor: 5.578

4.  Ventricular structure, function, and mechanics at high altitude: chronic remodeling in Sherpa vs. short-term lowlander adaptation.

Authors:  Mike Stembridge; Philip N Ainslie; Michael G Hughes; Eric J Stöhr; James D Cotter; Amanda Q X Nio; Rob Shave
Journal:  J Appl Physiol (1985)       Date:  2014-05-29

5.  Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc.

Authors:  Choongwon Jeong; Andrew T Ozga; David B Witonsky; Helena Malmström; Hanna Edlund; Courtney A Hofman; Richard W Hagan; Mattias Jakobsson; Cecil M Lewis; Mark S Aldenderfer; Anna Di Rienzo; Christina Warinner
Journal:  Proc Natl Acad Sci U S A       Date:  2016-06-20       Impact factor: 11.205

6.  Metabolic basis to Sherpa altitude adaptation.

Authors:  James A Horscroft; Aleksandra O Kotwica; Verena Laner; James A West; Philip J Hennis; Denny Z H Levett; David J Howard; Bernadette O Fernandez; Sarah L Burgess; Zsuzsanna Ament; Edward T Gilbert-Kawai; André Vercueil; Blaine D Landis; Kay Mitchell; Monty G Mythen; Cristina Branco; Randall S Johnson; Martin Feelisch; Hugh E Montgomery; Julian L Griffin; Michael P W Grocott; Erich Gnaiger; Daniel S Martin; Andrew J Murray
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-22       Impact factor: 11.205

Review 7.  Epigenomics and human adaptation to high altitude.

Authors:  Colleen G Julian
Journal:  J Appl Physiol (1985)       Date:  2017-08-17

8.  Genetic signatures of high-altitude adaptation in Tibetans.

Authors:  Jian Yang; Zi-Bing Jin; Jie Chen; Xiu-Feng Huang; Xiao-Man Li; Yuan-Bo Liang; Jian-Yang Mao; Xin Chen; Zhili Zheng; Andrew Bakshi; Dong-Dong Zheng; Mei-Qin Zheng; Naomi R Wray; Peter M Visscher; Fan Lu; Jia Qu
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-03       Impact factor: 11.205

9.  Ancestral Origins and Genetic History of Tibetan Highlanders.

Authors:  Dongsheng Lu; Haiyi Lou; Kai Yuan; Xiaoji Wang; Yuchen Wang; Chao Zhang; Yan Lu; Xiong Yang; Lian Deng; Ying Zhou; Qidi Feng; Ya Hu; Qiliang Ding; Yajun Yang; Shilin Li; Li Jin; Yaqun Guan; Bing Su; Longli Kang; Shuhua Xu
Journal:  Am J Hum Genet       Date:  2016-08-25       Impact factor: 11.025

10.  Admixture facilitates genetic adaptations to high altitude in Tibet.

Authors:  Choongwon Jeong; Gorka Alkorta-Aranburu; Buddha Basnyat; Maniraj Neupane; David B Witonsky; Jonathan K Pritchard; Cynthia M Beall; Anna Di Rienzo
Journal:  Nat Commun       Date:  2014       Impact factor: 14.919

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