Literature DB >> 21684568

Development of a 64 channel ultrasonic high frequency linear array imaging system.

ChangHong Hu1, Lequan Zhang, Jonathan M Cannata, Jesse Yen, K Kirk Shung.   

Abstract

In order to improve the lateral resolution and extend the field of view of a previously reported 48 element 30 MHz ultrasound linear array and 16-channel digital imaging system, the development of a 256 element 30 MHz linear array and an ultrasound imaging system with increased channel count has been undertaken. This paper reports the design and testing of a 64 channel digital imaging system which consists of an analog front-end pulser/receiver, 64 channels of Time-Gain Compensation (TGC), 64 channels of high-speed digitizer as well as a beamformer. A Personal Computer (PC) is used as the user interface to display real-time images. This system is designed as a platform for the purpose of testing the performance of high frequency linear arrays that have been developed in house. Therefore conventional approaches were taken it its implementation. Flexibility and ease of use are of primary concern whereas consideration of cost-effectiveness and novelty in design are only secondary. Even so, there are many issues at higher frequencies but do not exist at lower frequencies need to be solved. The system provides 64 channels of excitation pulsers while receiving simultaneously at a 20-120 MHz sampling rate to 12-bits. The digitized data from all channels are first fed through Field Programmable Gate Arrays (FPGAs), and then stored in memories. These raw data are accessed by the beamforming processor to re-build the image or to be downloaded to the PC for further processing. The beamformer that applies delays to the echoes of each channel is implemented with the strategy that combines coarse (8.3 ns) and fine delays (2 ns). The coarse delays are integer multiples of the sampling clock rate and are achieved by controlling the write enable pin of the First-In-First-Out (FIFO) memory to obtain valid beamforming data. The fine delays are accomplished with interpolation filters. This system is capable of achieving a maximum frame rate of 50 frames per second. Wire phantom images acquired with this system show a spatial resolution of 146 μm (lateral) and 54 μm (axial). Images with excised rabbit and pig eyeball as well as mouse embryo were also acquired to demonstrate its imaging capability.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 21684568      PMCID: PMC3190571          DOI: 10.1016/j.ultras.2011.05.010

Source DB:  PubMed          Journal:  Ultrasonics        ISSN: 0041-624X            Impact factor:   2.890


  9 in total

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Authors:  Marc Lukacs; Jianhua Yin; Guofeng Pang; Richard C Garcia; Emmanuel Cherin; Ross Williams; Jim Mehi; F Stuart Foster
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2006-10       Impact factor: 2.725

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Authors:  Arif Sanli Ergun; Yongli Huang; Xuefeng Zhuang; Omer Oralkan; Goksen G Yaralioglu; Butrus T Khuri-Yakub
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Authors:  Jonathan M Cannata; Jay A Williams; Qifa Zhou; Timothy A Ritter; K Kirk Shung
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2006-01       Impact factor: 2.725

5.  Development of a real-time, high-frequency ultrasound digital beamformer for high-frequency linear array transducers.

Authors:  Chang-Hong Hu; Xiao-Chen Xu; Jonathan M Cannata; Jesse T Yen; K Kirk Shung
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2006-02       Impact factor: 2.725

6.  A new 15-50 MHz array-based micro-ultrasound scanner for preclinical imaging.

Authors:  F Stuart Foster; James Mehi; Marc Lukacs; Desmond Hirson; Chris White; Chris Chaggares; Andrew Needles
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Authors:  Ira O Wygant; Nafis S Jamal; Hyunjoo J Lee; Amin Nikoozadeh; Omer Oralkan; Mustafa Karaman; Butrus T Khuri-Yakub
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2009-10       Impact factor: 2.725

8.  A high-frequency, high frame rate duplex ultrasound linear array imaging system for small animal imaging.

Authors:  Lequan Zhang; Xiaochen Xu; Changhong Hu; Lei Sun; Jesse T Yen; Jonathan M Cannata; K Kirk Shung
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2010-07       Impact factor: 2.725

9.  Ultrasound backscatter microscope analysis of early mouse embryonic brain development.

Authors:  D H Turnbull; T S Bloomfield; H S Baldwin; F S Foster; A L Joyner
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-14       Impact factor: 11.205

  9 in total
  6 in total

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2.  High-frequency dual mode pulsed wave Doppler imaging for monitoring the functional regeneration of adult zebrafish hearts.

Authors:  Bong Jin Kang; Jinhyoung Park; Jieun Kim; Hyung Ham Kim; Changyang Lee; Jae Youn Hwang; Ching-Ling Lien; K Kirk Shung
Journal:  J R Soc Interface       Date:  2015-02-06       Impact factor: 4.118

Review 3.  Electrical and Mechanical Strategies to Enable Cardiac Repair and Regeneration.

Authors:  Hung Cao; Bong Jin Kang; Chia-An Lee; K Kirk Shung; Tzung K Hsiai
Journal:  IEEE Rev Biomed Eng       Date:  2015-05-11

4.  Hemodynamics and ventricular function in a zebrafish model of injury and repair.

Authors:  Juhyun Lee; Hung Cao; Bong Jin Kang; Nelson Jen; Fei Yu; Chia-An Lee; Peng Fei; Jinhyoung Park; Shadi Bohlool; Lian Lash-Rosenberg; K Kirk Shung; Tzung K Hsiai
Journal:  Zebrafish       Date:  2014-10       Impact factor: 1.985

5.  Fabrication and Characterization of a 20-MHz Microlinear Phased-Array Transducer for Intervention Guidance.

Authors:  Chi Tat Chiu; Bong Jin Kang; Payam Eliahoo; Theodore Abraham; K Kirk Shung
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2017-05-29       Impact factor: 2.725

6.  Automated Segmentation of Light-Sheet Fluorescent Imaging to Characterize Experimental Doxorubicin-Induced Cardiac Injury and Repair.

Authors:  René R Sevag Packard; Kyung In Baek; Tyler Beebe; Nelson Jen; Yichen Ding; Feng Shi; Peng Fei; Bong Jin Kang; Po-Heng Chen; Jonathan Gau; Michael Chen; Jonathan Y Tang; Yu-Huan Shih; Yonghe Ding; Debiao Li; Xiaolei Xu; Tzung K Hsiai
Journal:  Sci Rep       Date:  2017-08-17       Impact factor: 4.379

  6 in total

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