Literature DB >> 21654818

SWI/SNF nucleosome remodellers and cancer.

Boris G Wilson1, Charles W M Roberts.   

Abstract

SWI/SNF chromatin remodelling complexes use the energy of ATP hydrolysis to remodel nucleosomes and to modulate transcription. Growing evidence indicates that these complexes have a widespread role in tumour suppression, as inactivating mutations in several SWI/SNF subunits have recently been identified at a high frequency in a variety of cancers. However, the mechanisms by which mutations in these complexes drive tumorigenesis are unclear. In this Review we discuss the contributions of SWI/SNF mutations to cancer formation, examine their normal functions and discuss opportunities for novel therapeutic interventions for SWI/SNF-mutant cancers.

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Year:  2011        PMID： 21654818     DOI： 10.1038/nrc3068

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  140 in total

1.  Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

Authors:  Tian H Chi; Mimi Wan; Keji Zhao; Ichiro Taniuchi; Lei Chen; Dan R Littman; Gerald R Crabtree
Journal:  Nature       Date:  2002-07-11       Impact factor: 49.962

2.  Structural analysis of the yeast SWI/SNF chromatin remodeling complex.

Authors:  Corey L Smith; Rachel Horowitz-Scherer; Joan F Flanagan; Christopher L Woodcock; Craig L Peterson
Journal:  Nat Struct Biol       Date:  2003-02

3.  Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice.

Authors:  C J Guidi; A T Sands; B P Zambrowicz; T K Turner; D A Demers; W Webster; T W Smith; A N Imbalzano; S N Jones
Journal:  Mol Cell Biol       Date:  2001-05       Impact factor: 4.272

4.  Five SWI genes are required for expression of the HO gene in yeast.

Authors:  M Stern; R Jensen; I Herskowitz
Journal:  J Mol Biol       Date:  1984-10-05       Impact factor: 5.469

5.  Polybromo protein BAF180 functions in mammalian cardiac chamber maturation.

Authors:  Zhong Wang; Weiguo Zhai; James A Richardson; Eric N Olson; Juanito J Meneses; Meri T Firpo; Chulho Kang; William C Skarnes; Robert Tjian
Journal:  Genes Dev       Date:  2004-12-15       Impact factor: 11.361

6.  Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.

Authors:  Siân Jones; Tian-Li Wang; Ie-Ming Shih; Tsui-Lien Mao; Kentaro Nakayama; Richard Roden; Ruth Glas; Dennis Slamon; Luis A Diaz; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu; Nickolas Papadopoulos
Journal:  Science       Date:  2010-09-08       Impact factor: 47.728

7.  Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

Authors:  Junya Fukuoka; Takeshi Fujii; Joanna H Shih; Tatiana Dracheva; Daoud Meerzaman; Audrey Player; Kyeong Hong; Sharon Settnek; Ajay Gupta; Kenneth Buetow; Stephen Hewitt; William D Travis; Jin Jen
Journal:  Clin Cancer Res       Date:  2004-07-01       Impact factor: 12.531

8.  Interaction of the glucocorticoid receptor with the chromatin landscape.

Authors:  Sam John; Peter J Sabo; Thomas A Johnson; Myong-Hee Sung; Simon C Biddie; Stafford L Lightman; Ty C Voss; Sean R Davis; Paul S Meltzer; John A Stamatoyannopoulos; Gordon L Hager
Journal:  Mol Cell       Date:  2008-03-14       Impact factor: 17.970

9.  Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).

Authors:  J C Reyes; J Barra; C Muchardt; A Camus; C Babinet; M Yaniv
Journal:  EMBO J       Date:  1998-12-01       Impact factor: 11.598

10.  Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.

Authors:  David N Reisman; Janiece Sciarrotta; Weidong Wang; William K Funkhouser; Bernard E Weissman
Journal:  Cancer Res       Date:  2003-02-01       Impact factor: 12.701
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  525 in total

1.  Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression.

Authors:  Fuhua Xu; Stephen Flowers; Elizabeth Moran
Journal:  J Biol Chem       Date:  2011-12-19       Impact factor: 5.157

2.  Cancer-fighting Smurf.

Authors:  Xi Wang; Charles W M Roberts
Journal:  Nat Med       Date:  2012-02-06       Impact factor: 53.440

Review 3.  Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes.

Authors:  Cedric R Clapier; Janet Iwasa; Bradley R Cairns; Craig L Peterson
Journal:  Nat Rev Mol Cell Biol       Date:  2017-05-17       Impact factor: 94.444

Review 4.  Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine.

Authors:  Erik S Knudsen; Eileen M O'Reilly; Jonathan R Brody; Agnieszka K Witkiewicz
Journal:  Gastroenterology       Date:  2015-09-15       Impact factor: 22.682

5.  Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress.

Authors:  Justin Wai-Chung Leung; Gargi Ghosal; Wenqi Wang; Xi Shen; Jiadong Wang; Lei Li; Junjie Chen
Journal:  J Biol Chem       Date:  2013-01-16       Impact factor: 5.157

6.  Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers.

Authors:  Gregory R Hoffman; Rami Rahal; Frank Buxton; Kay Xiang; Gregory McAllister; Elizabeth Frias; Linda Bagdasarian; Janina Huber; Alicia Lindeman; Dongshu Chen; Rodrigo Romero; Nadire Ramadan; Tanushree Phadke; Kristy Haas; Mariela Jaskelioff; Boris G Wilson; Matthew J Meyer; Veronica Saenz-Vash; Huili Zhai; Vic E Myer; Jeffery A Porter; Nicholas Keen; Margaret E McLaughlin; Craig Mickanin; Charles W M Roberts; Frank Stegmeier; Zainab Jagani
Journal:  Proc Natl Acad Sci U S A       Date:  2014-02-11       Impact factor: 11.205

Review 7.  Molecular markers in pediatric neuro-oncology.

Authors:  Koichi Ichimura; Ryo Nishikawa; Masao Matsutani
Journal:  Neuro Oncol       Date:  2012-09       Impact factor: 12.300

8.  Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions.

Authors:  Christopher J Lord; Niall Quinn; Colm J Ryan
Journal:  Elife       Date:  2020-05-28       Impact factor: 8.140

9.  Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.

Authors:  Tomomitsu Tahara; Eiichiro Yamamoto; Priyanka Madireddi; Hiromu Suzuki; Reo Maruyama; Woonbok Chung; Judith Garriga; Jaroslav Jelinek; Hiro-O Yamano; Tamotsu Sugai; Yutaka Kondo; Minoru Toyota; Jean-Pierre J Issa; Marcos R H Estécio
Journal:  Gastroenterology       Date:  2013-11-06       Impact factor: 22.682

10.  CARMA: CARM1 methylation of SWI/SNF in breast cancer.

Authors:  Xiaofeng Wang; Charles W M Roberts
Journal:  Cancer Cell       Date:  2014-01-13       Impact factor: 31.743
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