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Literature DB >> 21629285

US academic drug discovery.

Stephen Frye, Marina Crosby, Teresa Edwards, Rudolph Juliano.

Abstract

Entities: Disease Gene

Mesh：

Year: 2011 PMID： 21629285 PMCID： PMC4461005 DOI： 10.1038/nrd3462

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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13 in total

Review 1. The druggable genome.

Authors: Andrew L Hopkins; Colin R Groom
Journal: Nat Rev Drug Discov Date: 2002-09 Impact factor: 84.694

Review 2. How to improve R&D productivity: the pharmaceutical industry's grand challenge.

Authors: Steven M Paul; Daniel S Mytelka; Christopher T Dunwiddie; Charles C Persinger; Bernard H Munos; Stacy R Lindborg; Aaron L Schacht
Journal: Nat Rev Drug Discov Date: 2010-02-19 Impact factor: 84.694

3. Small molecules: the missing link in the central dogma.

Authors: Stuart L Schreiber
Journal: Nat Chem Biol Date: 2005-07 Impact factor: 15.040

4. Drug discovery in jeopardy.

Authors: Pedro Cuatrecasas
Journal: J Clin Invest Date: 2006-11 Impact factor: 14.808

5. Open access chemical and clinical probes to support drug discovery.

Authors: Aled M Edwards; Chas Bountra; David J Kerr; Timothy M Willson
Journal: Nat Chem Biol Date: 2009-07 Impact factor: 15.040

Review 6. Lessons from 60 years of pharmaceutical innovation.

Authors: Bernard Munos
Journal: Nat Rev Drug Discov Date: 2009-12 Impact factor: 84.694

7. The emerging academic drug-discovery sector.

Authors: Paul G Wyatt
Journal: Future Med Chem Date: 2009-09 Impact factor: 3.808

8. The role of public-sector research in the discovery of drugs and vaccines.

Authors: Ashley J Stevens; Jonathan J Jensen; Katrine Wyller; Patrick C Kilgore; Sabarni Chatterjee; Mark L Rohrbaugh
Journal: N Engl J Med Date: 2011-02-10 Impact factor: 91.245

9. Academia-industry partnerships in drug discovery.

Authors: Michael Dalrymple; Debbie Taylor; Catherine Kettleborough; Justin Bryans; Roberto Solari
Journal: Expert Opin Drug Discov Date: 2006-06 Impact factor: 6.098

Review 10. Integration of small-molecule discovery in academic biomedical research.

Authors: Michael Ohlmeyer; Ming-Ming Zhou
Journal: Mt Sinai J Med Date: 2010 Jul-Aug

27 in total

1. Computer-aided molecular design under the SWOTlight.

Authors: Darren V S Green; Andrew R Leach; Martha S Head
Journal: J Comput Aided Mol Des Date: 2011-12-15 Impact factor: 3.686

2. Academic-Industrial Collaboration: Toward the Consilience of Two Solitudes.

Authors: Stephen Hanessian
Journal: ACS Med Chem Lett Date: 2015-12-22 Impact factor: 4.345

3. Medicinal chemistry for 2020.

Authors: Seetharama D Satyanarayanajois; Ronald A Hill
Journal: Future Med Chem Date: 2011-10 Impact factor: 3.808

4. UK academic drug discovery.

Authors: Cathy Tralau-Stewart; Caroline M R Low; Nicola Marlin
Journal: Nat Rev Drug Discov Date: 2014-01 Impact factor: 84.694

5. QSAR modeling: where have you been? Where are you going to?

Authors: Artem Cherkasov; Eugene N Muratov; Denis Fourches; Alexandre Varnek; Igor I Baskin; Mark Cronin; John Dearden; Paola Gramatica; Yvonne C Martin; Roberto Todeschini; Viviana Consonni; Victor E Kuz'min; Richard Cramer; Romualdo Benigni; Chihae Yang; James Rathman; Lothar Terfloth; Johann Gasteiger; Ann Richard; Alexander Tropsha
Journal: J Med Chem Date: 2014-01-06 Impact factor: 7.446