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Literature DB >> 2159563

Evidence suggesting that virulence maps to the P1 region of the coxsackievirus B4 genome.

A Ramsingh¹, A Hixson, B Duceman, J Slack.

Abstract

A chimeric virus containing the P1 region of a virulent variant of coxsackievirus B4 and the P2 and P3 regions of a nonvirulent strain was constructed from cDNA clones. The chimeric virus induced pancreatitis with concurrent hypoglycemia similar to that observed in mice infected with the virulent variant.

Entities: Disease Species

Mesh：

Substances：

Year: 1990 PMID： 2159563 PMCID： PMC249496 DOI： 10.1128/JVI.64.6.3078-3081.1990

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

12 in total

1. On the enzymatic determination of blood glucose.

Authors: E RAABO; T C TERKILDSEN
Journal: Scand J Clin Lab Invest Date: 1960 Impact factor: 1.713

2. The complete nucleotide sequence of coxsackievirus B4 and its comparison to other members of the Picornaviridae.

Authors: O Jenkins; J D Booth; P D Minor; J W Almond
Journal: J Gen Virol Date: 1987-07 Impact factor: 3.891

Review 3. Enteroviruses in human disease.

Authors: N R Grist; E J Bell; F Assaad
Journal: Prog Med Virol Date: 1978

4. A recombinant virus between the Sabin 1 and Sabin 3 vaccine strains of poliovirus as a possible candidate for a new type 3 poliovirus live vaccine strain.

Authors: M Kohara; S Abe; T Komatsu; K Tago; M Arita; A Nomoto
Journal: J Virol Date: 1988-08 Impact factor: 5.103

5. Cloned poliovirus complementary DNA is infectious in mammalian cells.

Authors: V R Racaniello; D Baltimore
Journal: Science Date: 1981-11-20 Impact factor: 47.728

6. Theiler's murine encephalomyelitis virus neutralization escape mutants have a change in disease phenotype.

Authors: R P Roos; S Stein; M Routbort; A Senkowski; T Bodwell; R Wollmann
Journal: J Virol Date: 1989-10 Impact factor: 5.103

7. Increased neurovirulence associated with a single nucleotide change in a noncoding region of the Sabin type 3 poliovaccine genome.

Authors: D M Evans; G Dunn; P D Minor; G C Schild; A J Cann; G Stanway; J W Almond; K Currey; J V Maizel
Journal: Nature Date: 1985 Apr 11-17 Impact factor: 49.962

8. Molecular cloning of the genome of a cardiotropic Coxsackie B3 virus: full-length reverse-transcribed recombinant cDNA generates infectious virus in mammalian cells.

Authors: R Kandolf; P H Hofschneider
Journal: Proc Natl Acad Sci U S A Date: 1985-07 Impact factor: 11.205

9. Poliovirus type 1/type 3 antigenic hybrid virus constructed in vitro elicits type 1 and type 3 neutralizing antibodies in rabbits and monkeys.

Authors: M G Murray; R J Kuhn; M Arita; N Kawamura; A Nomoto; E Wimmer
Journal: Proc Natl Acad Sci U S A Date: 1988-05 Impact factor: 11.205

10. Virus-induced diabetes mellitus. XV. Beta cell damage and insulin-dependent hyperglycemia in mice infected with coxsackie virus B4.

Authors: J W Yoon; T Onodera; A L Notkins
Journal: J Exp Med Date: 1978-10-01 Impact factor: 14.307

10 in total

1. Mapping the genetic determinants of pathogenicity and plaque phenotype in swine vesicular disease virus.

Authors: T Kanno; D Mackay; T Inoue; G Wilsden; M Yamakawa; R Yamazoe; S Yamaguchi; J Shirai; P Kitching; Y Murakami
Journal: J Virol Date: 1999-04 Impact factor: 5.103

2. Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence.

Authors: S Tracy; K M Drescher; N M Chapman; K-S Kim; S D Carson; S Pirruccello; P H Lane; J R Romero; J S Leser
Journal: J Virol Date: 2002-12 Impact factor: 5.103

3. A point mutation in the VP4 coding sequence of coxsackievirus B4 influences virulence.

Authors: A I Ramsingh; D N Collins
Journal: J Virol Date: 1995-11 Impact factor: 5.103

4. Identification of a single amino acid residue in the capsid protein VP1 of coxsackievirus B4 that determines the virulent phenotype.

Authors: M Caggana; P Chan; A Ramsingh
Journal: J Virol Date: 1993-08 Impact factor: 5.103

5. Group B coxsackievirus diabetogenic phenotype correlates with replication efficiency.

Authors: Toru Kanno; Kisoon Kim; Ken Kono; Kristen M Drescher; Nora M Chapman; Steven Tracy
Journal: J Virol Date: 2006-06 Impact factor: 5.103

6. Direct evidence of a role for amino acid 101 of VP-1 in central nervous system disease in Theiler's murine encephalomyelitis virus infection.

Authors: A Zurbriggen; C Thomas; M Yamada; R P Roos; R S Fujinami
Journal: J Virol Date: 1991-04 Impact factor: 5.103

7. An infectious cDNA copy of the genome of a non-cardiovirulent coxsackievirus B3 strain: its complete sequence analysis and comparison to the genomes of cardiovirulent coxsackieviruses.

Authors: N M Chapman; Z Tu; S Tracy; C J Gauntt
Journal: Arch Virol Date: 1994 Impact factor: 2.574