Literature DB >> 2158188

Multiple sequence elements in the U3 region of the leukemogenic murine retrovirus SL3-2 contribute to cell-dependent gene expression.

H Y Dai1, M Etzerodt, A J Baekgaard, S Lovmand, P Jørgensen, N O Kjeldgaard, F S Pedersen.   

Abstract

Determination of the U3 sequence of the leukemogenic murine retrovirus SL3-2 revealed close relationships to SL3-3, Akv, and Gross passage A viruses. The SL3-2 and Akv regions showed wide differences in their relative transcriptional activity in four cell lines as determined by U3-driven transient expression assays. The U3 regions of SL3-2 and SL3-3 gave rise to similar but not identical levels of expression. Deletion mapping of the SL3-2 U3 region points to several determinants of expression of different relative importance in the cell lines tested.

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Year:  1990        PMID： 2158188     DOI： 10.1016/0042-6822(90)90445-w

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  12 in total

1.  Contributions to transcriptional activity and to viral leukemogenicity made by sequences within and downstream of the MCF13 murine leukemia virus enhancer.

Authors:  J C Tupper; H Chen; E F Hays; G C Bristol; F K Yoshimura
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

2.  Analysis of the significance of two single-base-pair differences in the SL3-3 and Akv virus long terminal repeats.

Authors:  H L Morrison; H Y Dai; F S Pedersen; J Lenz
Journal:  J Virol       Date:  1991-02       Impact factor: 5.103

3.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1990-09-11       Impact factor: 16.971

4.  Enhancer functions in U3 of Akv virus: a role for cooperativity of a tandem repeat unit and its flanking DNA sequences.

Authors:  S Lovmand; N O Kjeldgaard; P Jørgensen; F S Pedersen
Journal:  J Virol       Date:  1990-07       Impact factor: 5.103

5.  CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes.

Authors:  A L Zaiman; A Nieves; J Lenz
Journal:  J Virol       Date:  1998-04       Impact factor: 5.103

6.  A correlation between dexamethasone inducibility and basal expression levels of retroviral vector proviruses.

Authors:  M Duch; K Paludan; J Lovmand; L Pedersen; P Jørgensen; F S Pedersen
Journal:  Nucleic Acids Res       Date:  1993-10-11       Impact factor: 16.971

7.  E- vectors: development of novel self-inactivating and self-activating retroviral vectors for safer gene therapy.

Authors:  J G Julias; D Hash; V K Pathak
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

8.  B-Cell lymphoma induction by akv murine leukemia viruses harboring one or both copies of the tandem repeat in the U3 enhancer.

Authors:  J Lovmand; A B Sorensen; J Schmidt; M Ostergaard; A Luz; F S Pedersen
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103

9.  Molecular cloning of osteoma-inducing replication-competent murine leukemia viruses from the RFB osteoma virus stock.

Authors:  L Pedersen; W Behnisch; J Schmidt; A Luz; F S Pedersen; V Erfle; P G Strauss
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

10.  Inducible and cell type-specific expression of VL30 U3 subgroups correlate with their enhancer design.

Authors:  M Nilsson; S Bohm
Journal:  J Virol       Date:  1994-01       Impact factor: 5.103
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