Literature DB >> 1846181

Analysis of the significance of two single-base-pair differences in the SL3-3 and Akv virus long terminal repeats.

H L Morrison1, H Y Dai, F S Pedersen, J Lenz.   

Abstract

Two single-base-pair differences between the long terminal repeats (LTRs) of the T-lymphomagenic murine retrovirus SL3-3 and nonleukemogenic Akv virus were tested for effects on activity of the LTRs. Evidence was obtained from electrophoretic mobility shift assays for the presence of at least one factor in both T and non-T cells that bound to the region of the viral enhancers that contained the differences. However, no significant differences in activity in expression assays were detected when the two base-pair differences were exchanged between the two LTRs. Therefore, they do not contribute to the higher activity of the SL3-3 LTR in T-lymphoma cell lines.

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Year:  1991        PMID: 1846181      PMCID: PMC239851     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  33 in total

1.  A DNA element responsible for the different tissue specificities of Friend and Moloney retroviral enhancers.

Authors:  H J Thiesen; Z Bösze; L Henry; P Charnay
Journal:  J Virol       Date:  1988-02       Impact factor: 5.103

2.  Mutant analysis of protein interactions with a nuclear factor I binding site in the SL3-3 virus enhancer.

Authors:  P Nilsson; B Hallberg; A Thornell; T Grundström
Journal:  Nucleic Acids Res       Date:  1989-06-12       Impact factor: 16.971

3.  A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes.

Authors:  H Singh; R Sen; D Baltimore; P A Sharp
Journal:  Nature       Date:  1986 Jan 9-15       Impact factor: 49.962

4.  Murine leukemia virus long terminal repeat sequences can enhance gene activity in a cell-type-specific manner.

Authors:  F K Yoshimura; B Davison; K Chaffin
Journal:  Mol Cell Biol       Date:  1985-10       Impact factor: 4.272

5.  Correlation of leukemogenic potential of murine retroviruses with transcriptional tissue preference of the viral long terminal repeats.

Authors:  M K Short; S A Okenquist; J Lenz
Journal:  J Virol       Date:  1987-04       Impact factor: 5.103

6.  Differential protein binding in lymphocytes to a sequence in the enhancer of the mouse retrovirus SL3-3.

Authors:  A Thornell; B Hallberg; T Grundström
Journal:  Mol Cell Biol       Date:  1988-04       Impact factor: 4.272

7.  Two different factors act separately or together to specify functionally distinct activities at a single transcriptional enhancer.

Authors:  D DeFranco; K R Yamamoto
Journal:  Mol Cell Biol       Date:  1986-04       Impact factor: 4.272

8.  Tissue specific sequence motifs in the enhancer of the leukaemogenic mouse retrovirus SL3-3.

Authors:  B Hallberg; T Grundström
Journal:  Nucleic Acids Res       Date:  1988-07-11       Impact factor: 16.971

9.  Enhancer binding protein (EBP1) makes base and backbone contacts over one complete turn of the DNA double helix.

Authors:  L Clark; J Nicholson; R T Hay
Journal:  J Mol Biol       Date:  1989-04-20       Impact factor: 5.469

10.  Regulatory elements within the murine leukemia virus enhancer regions mediate glucocorticoid responsiveness.

Authors:  D Celander; B L Hsu; W A Haseltine
Journal:  J Virol       Date:  1988-04       Impact factor: 5.103

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  4 in total

1.  Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3.

Authors:  A Nieves; L S Levy; J Lenz
Journal:  J Virol       Date:  1997-02       Impact factor: 5.103

2.  Pathogenic determinants in the U3 region of recombinant murine leukemia viruses isolated from CWD and HRS/J mice.

Authors:  S C Lawrenz-Smith; A C Massey; D J Innes; C Y Thomas
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

3.  B-Cell lymphoma induction by akv murine leukemia viruses harboring one or both copies of the tandem repeat in the U3 enhancer.

Authors:  J Lovmand; A B Sorensen; J Schmidt; M Ostergaard; A Luz; F S Pedersen
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103

4.  A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions.

Authors:  Clifford L Wang; J Graeme Hodgson; Tiffany Malek; Finn Skou Pedersen; Matthias Wabl
Journal:  Retrovirology       Date:  2004-04-05       Impact factor: 4.602

  4 in total

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