Literature DB >> 21544222

Bioinspired Strong and Highly Porous Glass Scaffolds.

Qiang Fu1, Eduardo Saiz, Antoni P Tomsia.   

Abstract

The quest for more efficient energy-related technologies is driving the development of porous and high-performance structural materials with exceptional mechanical strength. Natural materials achieve their strength through complex hierarchical designs and anisotropic structures that are extremely difficult to replicate synthetically. We emulate nature's design by direct-ink-write assembling of glass scaffolds with a periodic pattern, and controlled sintering of the filaments into anisotropic constructs similar to biological materials. The final product is a porous glass scaffold with a compressive strength (136 MPa) comparable to that of cortical bone and a porosity (60%) comparable to that of trabecular bone. The strength of this porous glass scaffold is ~100 times that of polymer scaffolds and 4-5 times that of ceramic and glass scaffolds with comparable porosities reported elsewhere. The ability to create both porous and strong structures opens a new avenue for fabricating scaffolds for a broad array of applications, including tissue engineering, filtration, lightweight composites, and catalyst support.

Entities:  

Year:  2011        PMID: 21544222      PMCID: PMC3085453          DOI: 10.1002/adfm.201002030

Source DB:  PubMed          Journal:  Adv Funct Mater        ISSN: 1616-301X            Impact factor:   18.808


  39 in total

1.  The fabrication and characterization of linearly oriented nerve guidance scaffolds for spinal cord injury.

Authors:  Shula Stokols; Mark H Tuszynski
Journal:  Biomaterials       Date:  2004-12       Impact factor: 12.479

2.  Sintering and robocasting of beta-tricalcium phosphate scaffolds for orthopaedic applications.

Authors:  Pedro Miranda; Eduardo Saiz; Karol Gryn; Antoni P Tomsia
Journal:  Acta Biomater       Date:  2006-05-24       Impact factor: 8.947

3.  Biomimetic nerve scaffolds with aligned intraluminal microchannels: a "sweet" approach to tissue engineering.

Authors:  Jianming Li; Todd A Rickett; Riyi Shi
Journal:  Langmuir       Date:  2009-02-03       Impact factor: 3.882

4.  Preparation and in vitro evaluation of bioactive glass (13-93) scaffolds with oriented microstructures for repair and regeneration of load-bearing bones.

Authors:  Qiang Fu; Mohamed N Rahaman; B Sonny Bal; Roger F Brown
Journal:  J Biomed Mater Res A       Date:  2010-06-15       Impact factor: 4.396

Review 5.  Tissue engineering.

Authors:  R Langer; J P Vacanti
Journal:  Science       Date:  1993-05-14       Impact factor: 47.728

Review 6.  A review of the mechanical behavior of CaP and CaP/polymer composites for applications in bone replacement and repair.

Authors:  Amy J Wagoner Johnson; Brad A Herschler
Journal:  Acta Biomater       Date:  2010-07-21       Impact factor: 8.947

7.  Smart hydrogels for in situ generated implants.

Authors:  Daniel Cohn; Alejandro Sosnik; Shai Garty
Journal:  Biomacromolecules       Date:  2005 May-Jun       Impact factor: 6.988

8.  Concentrated hydroxyapatite inks for direct-write assembly of 3-D periodic scaffolds.

Authors:  Sarah Michna; Willie Wu; Jennifer A Lewis
Journal:  Biomaterials       Date:  2005-04-21       Impact factor: 12.479

9.  Proangiogenic potential of a collagen/bioactive glass substrate.

Authors:  Ann Leu; J Kent Leach
Journal:  Pharm Res       Date:  2007-11-30       Impact factor: 4.200

Review 10.  The design of mineralised hard tissues for their mechanical functions.

Authors:  J D Currey
Journal:  J Exp Biol       Date:  1999-12       Impact factor: 3.312

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  36 in total

Review 1.  Three-Dimensional-Printing of Bio-Inspired Composites.

Authors:  Grace Xiang Gu; Isabelle Su; Shruti Sharma; Jamie L Voros; Zhao Qin; Markus J Buehler
Journal:  J Biomech Eng       Date:  2016-02       Impact factor: 2.097

2.  Photo-active collagen systems with controlled triple helix architecture.

Authors:  Giuseppe Tronci; Stephen J Russell; David J Wood
Journal:  J Mater Chem B       Date:  2013-08-14       Impact factor: 6.331

3.  Mechanical properties of bioactive glass (13-93) scaffolds fabricated by robotic deposition for structural bone repair.

Authors:  Xin Liu; Mohamed N Rahaman; Gregory E Hilmas; B Sonny Bal
Journal:  Acta Biomater       Date:  2013-02-21       Impact factor: 8.947

Review 4.  Bioinspired structural materials.

Authors:  Ulrike G K Wegst; Hao Bai; Eduardo Saiz; Antoni P Tomsia; Robert O Ritchie
Journal:  Nat Mater       Date:  2014-10-26       Impact factor: 43.841

5.  Cellular Response to 3-D Printed Bioactive Silicate and Borosilicate Glass Scaffolds.

Authors:  Weitao Jia; Grace Y Lau; Wenhai Huang; Changqing Zhang; Antoni P Tomsia; Qiang Fu
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2018-09-08       Impact factor: 3.368

6.  Tough and strong porous bioactive glass-PLA composites for structural bone repair.

Authors:  Wei Xiao; Mohsen Asle Zaeem; Guangda Li; B Sonny Bal; Mohamed N Rahaman
Journal:  J Mater Sci       Date:  2017-01-17       Impact factor: 4.220

7.  Toward Strong and Tough Glass and Ceramic Scaffolds for Bone Repair.

Authors:  Qiang Fu; Eduardo Saiz; Mohamed N Rahaman; Antoni P Tomsia
Journal:  Adv Funct Mater       Date:  2013-06-13       Impact factor: 18.808

Review 8.  Advances in Optical Sensing and Bioanalysis Enabled by 3D Printing.

Authors:  Alexander Lambert; Santino Valiulis; Quan Cheng
Journal:  ACS Sens       Date:  2018-11-30       Impact factor: 7.711

9.  Direct ink writing of highly porous and strong glass scaffolds for load-bearing bone defects repair and regeneration.

Authors:  Qiang Fu; Eduardo Saiz; Antoni P Tomsia
Journal:  Acta Biomater       Date:  2011-06-28       Impact factor: 8.947

Review 10.  Dental applications of nanostructured bioactive glass and its composites.

Authors:  Alessandro Polini; Hao Bai; Antoni P Tomsia
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2013-04-18
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