Literature DB >> 21519421

Pharmacogenomics training using an instructional software system.

John A Springer1, Nicholas V Iannotti, Michael D Kane, Kevin Haynes, Jon E Sprague.   

Abstract

OBJECTIVES: To implement an elective course in pharmacogenomics designed to teach pharmacy students about the fundamentals of pharmacogenomics and the anticipated changes it will bring to the profession.
DESIGN: The 8 sessions of the course covered the basics of pharmacogenomics, genomic biotechnology, implementation of pharmacogenetics in pharmacy, information security and privacy, ethical issues related to the use of genomic data, pharmacoepidemiology, and use and promotion of GeneScription, a software program designed to mimic the professional pharmacy environment. ASSESSMENT: Student grades were based on completion of a patient education pamphlet, a 2-page paper on pharmacogenomics, and precourse and postcourse survey instruments. In the postcourse survey, all students strongly agreed that genomic data could be used to determine the optimal dose of a drug and genomic data for metabolizing enzymes could be stored in a safe place. Students also were more willing to submit deoxyribonucleic acid (DNA) data for genetic profiling and better understood how DNA analysis is performed after completing the course.
CONCLUSIONS: An elective course in pharmacogenomics equipped pharmacy students with the basic knowledge necessary to make clinical decisions based on pharmacogenomic data and to teach other healthcare professionals and patients about pharmacogenomics. For personalized medicine to become a reality, all pharmacists and pharmacy students must learn this knowledge and these skills.

Entities:  

Keywords:  drug safety; instructional software; personalized medicine; pharmacogenomics

Mesh:

Year:  2011        PMID: 21519421      PMCID: PMC3073107          DOI: 10.5688/ajpe75232

Source DB:  PubMed          Journal:  Am J Pharm Educ        ISSN: 0002-9459            Impact factor:   2.047


  9 in total

1.  Assessing the cost-effectiveness of pharmacogenomics.

Authors:  D L Veenstra; M K Higashi; K A Phillips
Journal:  AAPS PharmSci       Date:  2000

2.  Tailor-made pharmacotherapy: future developments and ethical challenges in the field of pharmacogenomics.

Authors:  Johannes van Delden; Ineke Bolt; Annemarie Kalis; Jeroen Derijks; Hubert Leufkens
Journal:  Bioethics       Date:  2004-08       Impact factor: 1.898

3.  Context, ethics and pharmacogenetics.

Authors:  Adam M Hedgecoe
Journal:  Stud Hist Philos Biol Biomed Sci       Date:  2006-08-23

Review 4.  Updated guidelines for manuscripts describing instructional design and assessment: the IDEAS format.

Authors:  Therese Poirier; Michael Crouch; George MacKinnon; Reza Mehvar; Mary Monk-Tutor
Journal:  Am J Pharm Educ       Date:  2009-05-27       Impact factor: 2.047

5.  The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism.

Authors:  T H Sullivan-Klose; B I Ghanayem; D A Bell; Z Y Zhang; L S Kaminsky; G M Shenfield; J O Miners; D J Birkett; J A Goldstein
Journal:  Pharmacogenetics       Date:  1996-08

6.  Genetic polymorphisms and functional characterization of the 5'-flanking region of the human CYP2C9 gene: in vitro and in vivo studies.

Authors:  M Shintani; I Ieiri; K Inoue; K Mamiya; H Ninomiya; N Tashiro; S Higuchi; K Otsubo
Journal:  Clin Pharmacol Ther       Date:  2001-08       Impact factor: 6.875

7.  Randomized trial of genotype-guided versus standard warfarin dosing in patients initiating oral anticoagulation.

Authors:  Jeffrey L Anderson; Benjamin D Horne; Scott M Stevens; Amanda S Grove; Stephanie Barton; Zachery P Nicholas; Samera F S Kahn; Heidi T May; Kent M Samuelson; Joseph B Muhlestein; John F Carlquist
Journal:  Circulation       Date:  2007-11-07       Impact factor: 29.690

8.  Applying health education theory to patient safety programs: three case studies.

Authors:  Melissa B Gilkey; Jo Anne L Earp; Elizabeth A French
Journal:  Health Promot Pract       Date:  2008-04

9.  CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: a prospective randomized controlled study.

Authors:  Y Caraco; S Blotnick; M Muszkat
Journal:  Clin Pharmacol Ther       Date:  2007-09-12       Impact factor: 6.875

  9 in total
  10 in total

1.  Pharmacogenomics Education Improves Pharmacy Student Perceptions of Their Abilities and Roles in Its Use.

Authors:  Rebecca Marcinak; Meaghan Paris; Shannon R M Kinney
Journal:  Am J Pharm Educ       Date:  2018-11       Impact factor: 2.047

2.  Challenges and Solutions for Future Pharmacy Practice in the Era of Precision Medicine.

Authors:  Olivia M Dong; Rachel M Howard; Rachel Church; Mackenzie Cottrell; Alan Forrest; Federico Innocenti; Merrie Mosedale; Angela Kashuba; Daniel Gonzalez; Tim Wiltshire
Journal:  Am J Pharm Educ       Date:  2018-08       Impact factor: 2.047

3.  Advancing Pharmacogenomics Education in the Core PharmD Curriculum through Student Personal Genomic Testing.

Authors:  Solomon M Adams; Kacey B Anderson; James C Coons; Randall B Smith; Susan M Meyer; Lisa S Parker; Philip E Empey
Journal:  Am J Pharm Educ       Date:  2016-02-25       Impact factor: 2.047

4.  An Effective Approach to Teaching Pharmacogenomics in the First Year of Pharmacy Curriculum.

Authors:  Marina Gálvez-Peralta; Grazyna D Szklarz; Werner J Geldenhuys; Paul R Lockman
Journal:  Am J Pharm Educ       Date:  2018-10       Impact factor: 2.047

5.  Primary care physicians' knowledge of and experience with pharmacogenetic testing.

Authors:  S B Haga; W Burke; G S Ginsburg; R Mills; R Agans
Journal:  Clin Genet       Date:  2012-07-03       Impact factor: 4.438

6.  Implementation of an Active-Learning Laboratory on Pharmacogenetics.

Authors:  Kacie E Powers; Tonya M Buffington; Daniel Contaifer; Dayanjan S Wijesinghe; Krista L Donohoe
Journal:  Am J Pharm Educ       Date:  2019-04       Impact factor: 2.047

7.  Balancing personalized medicine and personalized care.

Authors:  Kenneth Cornetta; Candy Gunther Brown
Journal:  Acad Med       Date:  2013-03       Impact factor: 6.893

8.  Pharmacogenomics: From classroom to practice.

Authors:  Samantha C Nutter; Marina Gálvez-Peralta
Journal:  Mol Genet Genomic Med       Date:  2018-05-31       Impact factor: 2.183

9.  Knowledge, Attitude, and Perceptions of Pharmacists and Pharmacy Students towards Pharmacogenomics in Zimbabwe.

Authors:  Nyasha Muzoriana; Samuel Gavi; Victoria Nembaware; Milcah Dhoro; Alice Matimba
Journal:  Pharmacy (Basel)       Date:  2017-06-30

10.  Knowledge, perceptions and confidence of physicians and pharmacists towards pharmacogenetics practice in Kuwait.

Authors:  Abdullah Albassam; Shahad Alshammari; Ghadeer Ouda; Samuel Koshy; Abdelmoneim Awad
Journal:  PLoS One       Date:  2018-09-05       Impact factor: 3.240

  10 in total

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