Literature DB >> 26941429

Advancing Pharmacogenomics Education in the Core PharmD Curriculum through Student Personal Genomic Testing.

Solomon M Adams1, Kacey B Anderson1, James C Coons2, Randall B Smith1, Susan M Meyer2, Lisa S Parker3, Philip E Empey2.   

Abstract

OBJECTIVE: To develop, implement, and evaluate "Test2Learn" a program to enhance pharmacogenomics education through the use of personal genomic testing (PGT) and real genetic data.
DESIGN: One hundred twenty-two second-year doctor of pharmacy (PharmD) students in a required course were offered PGT as part of a larger program approach to teach pharmacogenomics within a robust ethical framework. The program added novel learning objectives, lecture materials, analysis tools, and exercises using individual-level and population-level genetic data. Outcomes were assessed with objective measures and pre/post survey instruments. ASSESSMENT: One hundred students (82%) underwent PGT. Knowledge significantly improved on multiple assessments. Genotyped students reported a greater increase in confidence in understanding test results by the end of the course. Similarly, undergoing PGT improved student's self-perceived ability to empathize with patients compared to those not genotyped. Most students (71%) reported feeling PGT was an important part of the course, and 60% reported they had a better understanding of pharmacogenomics specifically because of the opportunity.
CONCLUSION: Implementation of PGT in the core pharmacy curriculum was feasible, well-received, and enhanced student learning of pharmacogenomics.

Entities:  

Keywords:  active learning; curriculum; genetics; personal genomic testing; pharmacogenomics

Mesh:

Year:  2016        PMID: 26941429      PMCID: PMC4776296          DOI: 10.5688/ajpe8013

Source DB:  PubMed          Journal:  Am J Pharm Educ        ISSN: 0002-9459            Impact factor:   2.047


  26 in total

1.  Establishment of the genetic/genomic competency center for education.

Authors:  Kathleen A Calzone; Bonnie Jerome-D'Emilia; Jean Jenkins; Constance Goldgar; Michael Rackover; John Jackson; Ye Chen; John Voss; W Gregory Feero
Journal:  J Nurs Scholarsh       Date:  2011-08-26       Impact factor: 3.176

2.  A genotyping exercise for pharmacogenetics in pharmacy practice.

Authors:  Daren L Knoell; Jeffrey S Johnston; Shengying Bao; Katherine A Kelley
Journal:  Am J Pharm Educ       Date:  2009-05-27       Impact factor: 2.047

3.  Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States.

Authors:  John E Murphy; James S Green; Laura A Adams; Robert B Squire; Grace M Kuo; Alan McKay
Journal:  Am J Pharm Educ       Date:  2010-02-10       Impact factor: 2.047

4.  Commentary: to genotype or not to genotype? Addressing the debate through the development of a genomics and personalized medicine curriculum.

Authors:  Keyan Salari; Philip A Pizzo; Charles G Prober
Journal:  Acad Med       Date:  2011-08       Impact factor: 6.893

5.  Evaluation of a shared pharmacogenomics curriculum for pharmacy students.

Authors:  Kelly C Lee; Karen Suchanek Hudmon; Joseph D Ma; Grace M Kuo
Journal:  Pharmacogenomics       Date:  2015       Impact factor: 2.533

Review 6.  Pharmacogenomics knowledge for personalized medicine.

Authors:  M Whirl-Carrillo; E M McDonagh; J M Hebert; L Gong; K Sangkuhl; C F Thorn; R B Altman; T E Klein
Journal:  Clin Pharmacol Ther       Date:  2012-10       Impact factor: 6.875

Review 7.  Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers.

Authors:  Henry M Dunnenberger; Kristine R Crews; James M Hoffman; Kelly E Caudle; Ulrich Broeckel; Scott C Howard; Robert J Hunkler; Teri E Klein; William E Evans; Mary V Relling
Journal:  Annu Rev Pharmacol Toxicol       Date:  2014-10-02       Impact factor: 13.820

8.  Medical and graduate students' attitudes toward personal genomics.

Authors:  Kelly E Ormond; Louanne Hudgins; Jennifer M Ladd; David M Magnus; Henry T Greely; Mildred K Cho
Journal:  Genet Med       Date:  2011-05       Impact factor: 8.822

9.  Ethical considerations regarding classroom use of personal genomic information.

Authors:  Lisa S Parker; Robin Grubs
Journal:  J Microbiol Biol Educ       Date:  2014-12-15

10.  Personal genome testing in medical education: student experiences with genotyping in the classroom.

Authors:  Simone Lucia Vernez; Keyan Salari; Kelly E Ormond; Sandra Soo-Jin Lee
Journal:  Genome Med       Date:  2013-03-19       Impact factor: 11.117

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  25 in total

1.  Clinical Pharmacogenomics: Applications in Nephrology.

Authors:  Solomon M Adams; Karryn R Crisamore; Philip E Empey
Journal:  Clin J Am Soc Nephrol       Date:  2018-05-23       Impact factor: 8.237

2.  Pharmacy students' attitudes and perceptions toward pharmacogenomics education.

Authors:  Shanice Coriolan; Nimota Arikawe; Arden Moscati; Lisheng Zhou; Stephanie Dym; Seda Donmez; Adinoyi Garba; Sasha Falbaum; Zvi Loewy; Melinda Lull; Maha Saad; Jane Shtaynberg; Aniwaa Owusu Obeng
Journal:  Am J Health Syst Pharm       Date:  2019-05-17       Impact factor: 2.637

3.  Pharmacogenomics courses in pharmacy school curricula.

Authors:  Susanne B Haga; Jivan Moaddeb
Journal:  Pharmacogenomics       Date:  2019-06       Impact factor: 2.533

4.  Pharmacogenomics Education Improves Pharmacy Student Perceptions of Their Abilities and Roles in Its Use.

Authors:  Rebecca Marcinak; Meaghan Paris; Shannon R M Kinney
Journal:  Am J Pharm Educ       Date:  2018-11       Impact factor: 2.047

Review 5.  Standardization can accelerate the adoption of pharmacogenomics: current status and the path forward.

Authors:  Kelly E Caudle; Nicholas J Keeling; Teri E Klein; Michelle Whirl-Carrillo; Victoria M Pratt; James M Hoffman
Journal:  Pharmacogenomics       Date:  2018-06-19       Impact factor: 2.533

6.  Challenges and Solutions for Future Pharmacy Practice in the Era of Precision Medicine.

Authors:  Olivia M Dong; Rachel M Howard; Rachel Church; Mackenzie Cottrell; Alan Forrest; Federico Innocenti; Merrie Mosedale; Angela Kashuba; Daniel Gonzalez; Tim Wiltshire
Journal:  Am J Pharm Educ       Date:  2018-08       Impact factor: 2.047

7.  An Effective Approach to Teaching Pharmacogenomics in the First Year of Pharmacy Curriculum.

Authors:  Marina Gálvez-Peralta; Grazyna D Szklarz; Werner J Geldenhuys; Paul R Lockman
Journal:  Am J Pharm Educ       Date:  2018-10       Impact factor: 2.047

8.  Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial.

Authors:  Rebecca C Pierson; Brandon T Gufford; Zeruesenay Desta; Michael T Eadon
Journal:  Pharmacogenomics       Date:  2017-06-08       Impact factor: 2.533

9.  Pharmacogenomics competencies in pharmacy practice: A blueprint for change.

Authors:  Mary W Roederer; Grace M Kuo; David F Kisor; Reginald F Frye; James M Hoffman; Jean Jenkins; Kristin Wiisanen Weitzel
Journal:  J Am Pharm Assoc (2003)       Date:  2016-11-03

10.  Participatory Genomic Testing Can Effectively Disseminate Cardiovascular Pharmacogenomics Concepts within Federally Qualified Health Centers: A Feasibility Study.

Authors:  Amber Johnson; Stephen Broughton; Lisa Aponte-Soto; Karriem Watson; Carla Da Goia Pinto; Philip Empey; Steven Reis; Robert Winn; Mylynda Massart
Journal:  Ethn Dis       Date:  2020-04-02       Impact factor: 1.847

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