Literature DB >> 30181675

Challenges and Solutions for Future Pharmacy Practice in the Era of Precision Medicine.

Olivia M Dong1,2, Rachel M Howard1,2, Rachel Church1, Mackenzie Cottrell1, Alan Forrest1, Federico Innocenti1,2, Merrie Mosedale1, Angela Kashuba1, Daniel Gonzalez1, Tim Wiltshire1,2,3.   

Abstract

As precision medicine research and its clinical applications continue to advance, it is critical for pharmacists to be involved in these developments to deliver optimal, tailored drug therapies for patients. To ensure pharmacists remain leaders in the field, the annual Pharmaceutical Sciences Conference convened by the University of North Carolina at Chapel Hill Eshelman School of Pharmacy focused on the role of pharmacy within precision medicine. This is a summary of the conference, highlighting the major challenges and solutions that will help advance individualized pharmacological methods within practice and research.

Entities:  

Keywords:  conference; pharmaceutical sciences; precision medicine

Mesh:

Year:  2018        PMID: 30181675      PMCID: PMC6116878          DOI: 10.5688/ajpe6652

Source DB:  PubMed          Journal:  Am J Pharm Educ        ISSN: 0002-9459            Impact factor:   2.047


  16 in total

1.  Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study.

Authors:  Frederick E Dewey; Michael F Murray; John D Overton; Lukas Habegger; Joseph B Leader; Samantha N Fetterolf; Colm O'Dushlaine; Cristopher V Van Hout; Jeffrey Staples; Claudia Gonzaga-Jauregui; Raghu Metpally; Sarah A Pendergrass; Monica A Giovanni; H Lester Kirchner; Suganthi Balasubramanian; Noura S Abul-Husn; Dustin N Hartzel; Daniel R Lavage; Korey A Kost; Jonathan S Packer; Alexander E Lopez; John Penn; Semanti Mukherjee; Nehal Gosalia; Manoj Kanagaraj; Alexander H Li; Lyndon J Mitnaul; Lance J Adams; Thomas N Person; Kavita Praveen; Anthony Marcketta; Matthew S Lebo; Christina A Austin-Tse; Heather M Mason-Suares; Shannon Bruse; Scott Mellis; Robert Phillips; Neil Stahl; Andrew Murphy; Aris Economides; Kimberly A Skelding; Christopher D Still; James R Elmore; Ingrid B Borecki; George D Yancopoulos; F Daniel Davis; William A Faucett; Omri Gottesman; Marylyn D Ritchie; Alan R Shuldiner; Jeffrey G Reid; David H Ledbetter; Aris Baras; David J Carey
Journal:  Science       Date:  2016-12-23       Impact factor: 47.728

Review 2.  Scalpels not hammers: The way forward for precision drug prescription.

Authors:  M Neely
Journal:  Clin Pharmacol Ther       Date:  2017-01-23       Impact factor: 6.875

3.  Advancing Pharmacogenomics Education in the Core PharmD Curriculum through Student Personal Genomic Testing.

Authors:  Solomon M Adams; Kacey B Anderson; James C Coons; Randall B Smith; Susan M Meyer; Lisa S Parker; Philip E Empey
Journal:  Am J Pharm Educ       Date:  2016-02-25       Impact factor: 2.047

4.  The role of hospital pharmacists in the adoption and use of pharmacogenomics and precision medicine.

Authors:  Emily J Schwartz; Amalia M Issa
Journal:  Per Med       Date:  2016-10-19       Impact factor: 2.512

Review 5.  Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers.

Authors:  Henry M Dunnenberger; Kristine R Crews; James M Hoffman; Kelly E Caudle; Ulrich Broeckel; Scott C Howard; Robert J Hunkler; Teri E Klein; William E Evans; Mary V Relling
Journal:  Annu Rev Pharmacol Toxicol       Date:  2014-10-02       Impact factor: 13.820

6.  The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?

Authors:  Elizabeth O Lillie; Bradley Patay; Joel Diamant; Brian Issell; Eric J Topol; Nicholas J Schork
Journal:  Per Med       Date:  2011-03       Impact factor: 2.512

7.  Improved Tacrolimus Target Concentration Achievement Using Computerized Dosing in Renal Transplant Recipients--A Prospective, Randomized Study.

Authors:  Elisabet Størset; Anders Åsberg; Morten Skauby; Michael Neely; Stein Bergan; Sara Bremer; Karsten Midtvedt
Journal:  Transplantation       Date:  2015-10       Impact factor: 4.939

Review 8.  Emerging roles for pharmacists in clinical implementation of pharmacogenomics.

Authors:  Aniwaa Owusu-Obeng; Kristin W Weitzel; Randy C Hatton; Benjamin J Staley; Jennifer Ashton; Rhonda M Cooper-Dehoff; Julie A Johnson
Journal:  Pharmacotherapy       Date:  2014-09-15       Impact factor: 4.705

9.  Metabolomics enables precision medicine: "A White Paper, Community Perspective".

Authors:  Richard D Beger; Warwick Dunn; Michael A Schmidt; Steven S Gross; Jennifer A Kirwan; Marta Cascante; Lorraine Brennan; David S Wishart; Matej Oresic; Thomas Hankemeier; David I Broadhurst; Andrew N Lane; Karsten Suhre; Gabi Kastenmüller; Susan J Sumner; Ines Thiele; Oliver Fiehn; Rima Kaddurah-Daouk
Journal:  Metabolomics       Date:  2016-09-02       Impact factor: 4.290

Review 10.  Precision Dosing: Public Health Need, Proposed Framework, and Anticipated Impact.

Authors:  Daniel Gonzalez; Gauri G Rao; Stacy C Bailey; Kim L R Brouwer; Yanguang Cao; Daniel J Crona; Angela D M Kashuba; Craig R Lee; Kathryn Morbitzer; J Herbert Patterson; Tim Wiltshire; Jon Easter; Scott W Savage; J Robert Powell
Journal:  Clin Transl Sci       Date:  2017-08-10       Impact factor: 4.689

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  1 in total

1.  Projected impact of a multigene pharmacogenetic test to optimize medication prescribing in cardiovascular patients.

Authors:  Olivia M Dong; Amy Li; Oscar Suzuki; Akinyemi Oni-Orisan; Ricardo Gonzalez; George A Stouffer; Craig R Lee; Tim Wiltshire
Journal:  Pharmacogenomics       Date:  2018-05-25       Impact factor: 2.533

  1 in total

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