Renaud de Tayrac1, Vincent Letouzey. 1. Obstetrics and Gynaecology Department, Caremeau University Hospital, Nîmes, France. renaud.detayrac@chu-nimes.fr
Abstract
INTRODUCTION AND HYPOTHESIS: Bacterial colonization following mesh-augmented pelvic floor reconstructive surgery for pelvic organ prolapse is probably an underestimated consideration. METHODS: Although clinical infections are rare, subclinical contamination of the polypropylene mesh has been systematically demonstrated by bacteriological analyses during mesh implantation and on explanted meshes. RESULTS: A model of subclinical mesh infection does exist and bacterial colonization and mesh shrinkage have recently been correlated experimentally. CONCLUSIONS: New meshes with surface modifications or an antibiotic or antiseptic coating should be explored.
INTRODUCTION AND HYPOTHESIS: Bacterial colonization following mesh-augmented pelvic floor reconstructive surgery for pelvic organ prolapse is probably an underestimated consideration. METHODS: Although clinical infections are rare, subclinical contamination of the polypropylene mesh has been systematically demonstrated by bacteriological analyses during mesh implantation and on explanted meshes. RESULTS: A model of subclinical mesh infection does exist and bacterial colonization and mesh shrinkage have recently been correlated experimentally. CONCLUSIONS: New meshes with surface modifications or an antibiotic or antiseptic coating should be explored.
Authors: Jiongyu Ren; Rebecca Murray; Cynthia S Wong; Jilong Qin; Michael Chen; Makrina Totsika; Andrew D Riddell; Andrea Warwick; Nicholas Rukin; Maria A Woodruff Journal: Polymers (Basel) Date: 2022-02-16 Impact factor: 4.329