PURPOSE: To measure and compare cortical and medullary T1 values in native and transplanted kidneys with a wide range of function as measured by estimated glomerular filtration rate (eGFR). MATERIALS AND METHODS: A total of 27 subjects (12 native and 15 transplants) were studied. Two magnetic resonance imaging (MRI) exams of T1 measurement were performed on separate days for reproducibility study. Group-wise comparisons of renal T1 on day 1 were performed between subjects with native and transplanted kidneys and also between subjects based on an eGFR threshold of 60 mL/min/1.73 m(2). RESULTS: Transplanted kidneys had higher cortical renal T1 (1183 ± 136 msec) than native kidneys (1057 ± 94 msec) with similar results in the medulla. Subjects with an eGFR < 60 mL/min/1.73 m(2) had higher renal T1 than subjects with an eGFR > 60 mL/min/1.73 m(2) (cortical T1: P < 0.0001; medullary T1: P = 0.008). Renal T1 was highly reproducible for both native and transplant groups (with percent differences less than 10%). CONCLUSION: There are differences in cortical and medullary T1 between native and transplanted kidneys at different levels of function.
PURPOSE: To measure and compare cortical and medullary T1 values in native and transplanted kidneys with a wide range of function as measured by estimated glomerular filtration rate (eGFR). MATERIALS AND METHODS: A total of 27 subjects (12 native and 15 transplants) were studied. Two magnetic resonance imaging (MRI) exams of T1 measurement were performed on separate days for reproducibility study. Group-wise comparisons of renal T1 on day 1 were performed between subjects with native and transplanted kidneys and also between subjects based on an eGFR threshold of 60 mL/min/1.73 m(2). RESULTS: Transplanted kidneys had higher cortical renal T1 (1183 ± 136 msec) than native kidneys (1057 ± 94 msec) with similar results in the medulla. Subjects with an eGFR < 60 mL/min/1.73 m(2) had higher renal T1 than subjects with an eGFR > 60 mL/min/1.73 m(2) (cortical T1: P < 0.0001; medullary T1: P = 0.008). Renal T1 was highly reproducible for both native and transplant groups (with percent differences less than 10%). CONCLUSION: There are differences in cortical and medullary T1 between native and transplanted kidneys at different levels of function.
Authors: J A Detre; W Zhang; D A Roberts; A C Silva; D S Williams; D J Grandis; A P Koretsky; J S Leigh Journal: NMR Biomed Date: 1994-03 Impact factor: 4.044
Authors: Matti Peperhove; Van Dai Vo Chieu; Mi-Sun Jang; Marcel Gutberlet; Dagmar Hartung; Susanne Tewes; Gregor Warnecke; Christiane Fegbeutel; Axel Haverich; Wilfried Gwinner; Frank Lehner; Jan Hinrich Bräsen; Hermann Haller; Frank Wacker; Faikah Gueler; Katja Hueper Journal: Eur Radiol Date: 2017-07-14 Impact factor: 5.315
Authors: Isabell K Bones; Anita A Harteveld; Suzanne L Franklin; Matthias J P van Osch; Jeroen Hendrikse; Chrit T W Moonen; Clemens Bos; Marijn van Stralen Journal: Magn Reson Med Date: 2019-03-18 Impact factor: 4.668
Authors: Felix Lugauer; Jens Wetzl; Christoph Forman; Manuel Schneider; Berthold Kiefer; Joachim Hornegger; Dominik Nickel; Andreas Maier Journal: MAGMA Date: 2018-01-25 Impact factor: 2.310
Authors: Tobias Breidthardt; Eleanor F Cox; Iain Squire; Aghogho Odudu; Nur Farhayu Omar; Mohamed Tarek Eldehni; Susan T Francis; Christopher W McIntyre Journal: Eur Radiol Date: 2015-01-11 Impact factor: 5.315
Authors: Yong Chen; Yun Jiang; Shivani Pahwa; Dan Ma; Lan Lu; Michael D Twieg; Katherine L Wright; Nicole Seiberlich; Mark A Griswold; Vikas Gulani Journal: Radiology Date: 2016-01-21 Impact factor: 11.105
Authors: David J Niles; Nathan S Artz; Arjang Djamali; Elizabeth A Sadowski; Thomas M Grist; Sean B Fain Journal: Invest Radiol Date: 2016-02 Impact factor: 6.016