PURPOSE: To evaluate renal corticomedullary differentiation (CMD) in patients with differing serum creatinine (sCr) levels. MATERIALS AND METHODS: Ten patients with normal sCr levels (0.9-1.3 mg/dL [80-115 mumol/L]), 14 with mildly elevated levels (1.5-2.9 mg/dL [133-256 mumol/L]), and 15 with elevated levels (> 3.0 mg/dL [265 mumol/L]) were examined with unenhanced T1-weighted fat-suppressed spin-echo (T1FS) and immediate gadolinium-enhanced gradient-echo (Gd-GRE) imaging. RESULTS: Patients with normal sCr levels had CMD on T1FS and Gd-GRE images. Among patients with mildly elevated levels, seven did and seven did not have CMD on T1FS images; all had CMD on Gd-GRE images. Patients with elevated levels had no CMD on T1FS images; 13 had CMD on Gd-GRE images. Two patients with levels above 10.0 mg/dL (884 mumol/L) had no CMD on Gd-GRE images. CONCLUSION: Independent of the cause of elevated sCr level, levels above 3.0 mg/dL result in loss of CMD on T1FS images, while levels above 10.0 mg/dL result in loss of CMD on Gd-GRE images.
PURPOSE: To evaluate renal corticomedullary differentiation (CMD) in patients with differing serum creatinine (sCr) levels. MATERIALS AND METHODS: Ten patients with normal sCr levels (0.9-1.3 mg/dL [80-115 mumol/L]), 14 with mildly elevated levels (1.5-2.9 mg/dL [133-256 mumol/L]), and 15 with elevated levels (> 3.0 mg/dL [265 mumol/L]) were examined with unenhanced T1-weighted fat-suppressed spin-echo (T1FS) and immediate gadolinium-enhanced gradient-echo (Gd-GRE) imaging. RESULTS:Patients with normal sCr levels had CMD on T1FS and Gd-GRE images. Among patients with mildly elevated levels, seven did and seven did not have CMD on T1FS images; all had CMD on Gd-GRE images. Patients with elevated levels had no CMD on T1FS images; 13 had CMD on Gd-GRE images. Two patients with levels above 10.0 mg/dL (884 mumol/L) had no CMD on Gd-GRE images. CONCLUSION: Independent of the cause of elevated sCr level, levels above 3.0 mg/dL result in loss of CMD on T1FS images, while levels above 10.0 mg/dL result in loss of CMD on Gd-GRE images.
Authors: Matti Peperhove; Van Dai Vo Chieu; Mi-Sun Jang; Marcel Gutberlet; Dagmar Hartung; Susanne Tewes; Gregor Warnecke; Christiane Fegbeutel; Axel Haverich; Wilfried Gwinner; Frank Lehner; Jan Hinrich Bräsen; Hermann Haller; Frank Wacker; Faikah Gueler; Katja Hueper Journal: Eur Radiol Date: 2017-07-14 Impact factor: 5.315
Authors: Karen S Lee; Amelia Muñoz; Adán Bello Báez; Long Ngo; Neil M Rofsky; Ivan Pedrosa Journal: J Magn Reson Imaging Date: 2011-10-26 Impact factor: 4.813
Authors: Yin Huang; Elizabeth A Sadowski; Nathan S Artz; Songwon Seo; Arjang Djamali; Thomas M Grist; Sean B Fain Journal: J Magn Reson Imaging Date: 2011-05 Impact factor: 4.813
Authors: Marcos Wolf; Anneloes de Boer; Kanishka Sharma; Peter Boor; Tim Leiner; Gere Sunder-Plassmann; Ewald Moser; Anna Caroli; Neil Peter Jerome Journal: Nephrol Dial Transplant Date: 2018-09-01 Impact factor: 5.992