Literature DB >> 21500849

Fusarisetin A, an acinar morphogenesis inhibitor from a soil fungus, Fusarium sp. FN080326.

Jae-Hyuk Jang1, Yukihiro Asami, Jun-Pil Jang, Sun-Ok Kim, Dong Oh Moon, Kee-Sun Shin, Daisuke Hashizume, Makoto Muroi, Tamio Saito, Hyuncheol Oh, Bo Yeon Kim, Hiroyuki Osada, Jong Seog Ahn.   

Abstract

An acinar morphogenesis inhibitor named fusarisetin A (1) that possesses both an unprecedented carbon skeleton and a new pentacyclic ring system has been identified from an in-house fractionated fungal library using a three-dimensional matrigel-induced acinar morphogenesis assay system. The structure of 1 was determined in detail by NMR and circular dichroism spectroscopy, X-ray analysis, and chemical reaction experiments.
© 2011 American Chemical Society

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Year:  2011        PMID： 21500849     DOI： 10.1021/ja1110688

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  17 in total

1.  Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058.

Authors:  Toshihiko Nogawa; Naoki Kato; Takeshi Shimizu; Akiko Okano; Yushi Futamura; Shunji Takahashi; Hiroyuki Osada
Journal:  J Antibiot (Tokyo)       Date:  2017-09-13       Impact factor: 2.649

2.  Nature-inspired total synthesis of (-)-fusarisetin A.

Authors:  Jing Xu; Eduardo J E Caro-Diaz; Lynnie Trzoss; Emmanuel A Theodorakis
Journal:  J Am Chem Soc       Date:  2012-03-08       Impact factor: 15.419

3.  Navigating the fungal polyketide chemical space: from genes to molecules.

Authors:  Yit-Heng Chooi; Yi Tang
Journal:  J Org Chem       Date:  2012-09-13       Impact factor: 4.354

Review 4.  Recent advances of Diels-Alderases involved in natural product biosynthesis.

Authors:  Atsushi Minami; Hideaki Oikawa
Journal:  J Antibiot (Tokyo)       Date:  2016-06-15       Impact factor: 2.649

5.  Fusarisetin A: Scalable Total Synthesis and Related Studies.

Authors:  Jing Xu; Eduardo J E Caro-Diaz; Michelle H Lacoske; Chao-I Hung; Colin Jamora; Emmanuel A Theodorakis
Journal:  Chem Sci       Date:  2012-08-23       Impact factor: 9.825

6.  Synthetic Strategies Toward the Decalin Motif of Maklamicin and Related Spirotetronates.

Authors:  Michelle H Lacoske; Jing Xu; Noel Mansour; Chao Gao; Emmanuel A Theodorakis
Journal:  Org Chem Front       Date:  2015-04-01       Impact factor: 5.281

7.  Fusarisetins: Structure-function studies on a novel class of cell migration inhibitors.

Authors:  Eduardo J E Caro-Diaz; Aereas Aung; Jing Xu; Shyni Varghese; Emmanuel A Theodorakis
Journal:  Org Chem Front       Date:  2014-04-01       Impact factor: 5.281

8.  Construction of Polycyclic γ-Lactams and Related Heterocycles via Electron Catalysis.

Authors:  Jun Xuan; Constantin G Daniliuc; Armido Studer
Journal:  Org Lett       Date:  2016-11-29       Impact factor: 6.005

Review 9.  The Biological and Chemical Diversity of Tetramic Acid Compounds from Marine-Derived Microorganisms.

Authors:  Minghua Jiang; Senhua Chen; Jing Li; Lan Liu
Journal:  Mar Drugs       Date:  2020-02-15       Impact factor: 5.118

10.  Pyrenosetin D, a New Pentacyclic Decalinoyltetramic Acid Derivative from the Algicolous Fungus Pyrenochaetopsis sp. FVE-087.

Authors:  Bicheng Fan; Pradeep Dewapriya; Fengjie Li; Laura Grauso; Martina Blümel; Alfonso Mangoni; Deniz Tasdemir
Journal:  Mar Drugs       Date:  2020-05-26       Impact factor: 5.118
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