Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Brain mechanisms for processing direct and averted gaze in individuals with autism.

Literature DB >> 21484518

Brain mechanisms for processing direct and averted gaze in individuals with autism.

Naomi B Pitskel¹, Danielle Z Bolling, Caitlin M Hudac, Stephen D Lantz, Nancy J Minshew, Brent C Vander Wyk, Kevin A Pelphrey.

Abstract

Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos depicting a simple but realistic social scenario, in which an approaching male figure maintained either direct or averted gaze. Significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. Our results provide initial evidence regarding brain mechanisms underlying the processing of gaze direction during simple social encounters, providing new insight into the social deficits in individuals with autism.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2011 PMID： 21484518 PMCID： PMC3337548 DOI： 10.1007/s10803-011-1197-x

Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257

54 in total

1. Reading the mind from eye gaze.

Authors: Andrew J Calder; Andrew D Lawrence; Jill Keane; Sophie K Scott; Adrian M Owen; Ingrid Christoffels; Andrew W Young
Journal: Neuropsychologia Date: 2002 Impact factor: 3.139

2. Voluntary orienting is dissociated from target detection in human posterior parietal cortex.

Authors: M Corbetta; J M Kincade; J M Ollinger; M P McAvoy; G L Shulman
Journal: Nat Neurosci Date: 2000-03 Impact factor: 24.884

3. Cortical regions involved in eye movements, shifts of attention, and gaze perception.

Authors: Marie-Hélène Grosbras; Angela R Laird; Tomás Paus
Journal: Hum Brain Mapp Date: 2005-05 Impact factor: 5.038

4. When eye creates the contact! ERP evidence for early dissociation between direct and averted gaze motion processing.

Authors: Laurence Conty; Karim N'Diaye; Charles Tijus; Nathalie George
Journal: Neuropsychologia Date: 2007-06-12 Impact factor: 3.139

5. Electrophysiological studies of human face perception. II: Response properties of face-specific potentials generated in occipitotemporal cortex.

Authors: G McCarthy; A Puce; A Belger; T Allison
Journal: Cereb Cortex Date: 1999 Jul-Aug Impact factor: 5.357

6. The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism.

Authors: C Lord; S Risi; L Lambrecht; E H Cook; B L Leventhal; P C DiLavore; A Pickles; M Rutter
Journal: J Autism Dev Disord Date: 2000-06

7. When strangers pass: processing of mutual and averted social gaze in the superior temporal sulcus.

Authors: Kevin A Pelphrey; Ronald J Viola; Gregory McCarthy
Journal: Psychol Sci Date: 2004-09

8. Severe impairments of social interaction and associated abnormalities in children: epidemiology and classification.

Authors: L Wing; J Gould
Journal: J Autism Dev Disord Date: 1979-03

9. Eye contact detection in humans from birth.

Authors: Teresa Farroni; Gergely Csibra; Francesca Simion; Mark H Johnson
Journal: Proc Natl Acad Sci U S A Date: 2002-06-24 Impact factor: 11.205

10. Can machines think? Interaction and perspective taking with robots investigated via fMRI.

Authors: Sören Krach; Frank Hegel; Britta Wrede; Gerhard Sagerer; Ferdinand Binkofski; Tilo Kircher
Journal: PLoS One Date: 2008-07-09 Impact factor: 3.240

37 in total

1. Atypical brain activation patterns during a face-to-face joint attention game in adults with autism spectrum disorder.

Authors: Elizabeth Redcay; David Dodell-Feder; Penelope L Mavros; Mario Kleiner; Mark J Pearrow; Christina Triantafyllou; John D Gabrieli; Rebecca Saxe
Journal: Hum Brain Mapp Date: 2012-04-16 Impact factor: 5.038

2. Analysis of cortical shape in children with simplex autism.

Authors: Donna L Dierker; Eric Feczko; John R Pruett; Steven E Petersen; Bradley L Schlaggar; John N Constantino; John W Harwell; Timothy S Coalson; David C Van Essen
Journal: Cereb Cortex Date: 2013-10-27 Impact factor: 5.357

3. No Evidence of Emotional Dysregulation or Aversion to Mutual Gaze in Preschoolers with Autism Spectrum Disorder: An Eye-Tracking Pupillometry Study.

Authors: Heather J Nuske; Giacomo Vivanti; Cheryl Dissanayake
Journal: J Autism Dev Disord Date: 2015-11

4. Preserved Self-other Distinction During Empathy in Autism is Linked to Network Integrity of Right Supramarginal Gyrus.

Authors: Ferdinand Hoffmann; Svenja Koehne; Nikolaus Steinbeis; Isabel Dziobek; Tania Singer
Journal: J Autism Dev Disord Date: 2016-02

5. Approximating implicit and explicit mentalizing with two naturalistic video-based tasks in typical development and autism spectrum disorder.

Authors: Gabriela Rosenblau; Dorit Kliemann; Hauke R Heekeren; Isabel Dziobek
Journal: J Autism Dev Disord Date: 2015-04