Literature DB >> 21481162

Combining ketamine and virtual reality pain control during severe burn wound care: one military and one civilian patient.

Christopher V Maani1, Hunter G Hoffman, Marcie Fowler, Alan J Maiers, Kathryn M Gaylord, Peter A Desocio.   

Abstract

BACKGROUND: US soldiers injured in Iraq, and civilian burn trauma patients are treated at the US Army Institute of Surgical Research. Burn patients experience extreme pain during wound care, and they typically receive opioid analgesics and anxiolytics for debridement. Virtual Reality (VR) has been applied as an adjunct to opioid analgesics for procedural pain. We describe the first use of ketamine combined with immersive VR to reduce excessive pain during wound care. CASE REPORT: A 21-year-old male US Army soldier stationed in Iraq, and a 41-year-old civilian male sustained a 13% and 50% total body surface area (TBSA) burn, respectively. Each patient received 40 mg ketamine intraveneous (IV) for wound care. Using a within-subject design, nurses conducted half of a painful segment of wound care treatments with no VR and the other half with immersive VR. Graphic pain rating scores for each of the two treatment conditions served as the dependent variables.
RESULTS: Compared to ketamine + no VR, both patients reported less pain during ketamine + VR for all three pain ratings. Both patients rated wound care during no VR as "no fun at all", but those same patients rated wound care during virtual reality as either "pretty fun" or "extremely fun", and rated nausea as either "mild" or "none".
CONCLUSIONS: Results from these first two cases suggest that a moderate dose of ketamine combined with immersive virtual reality distraction may be an effective multimodal analgesic regimen for reducing acute procedural pain during severe burn wound cleaning. Wiley Periodicals, Inc.

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Year:  2011        PMID: 21481162      PMCID: PMC4460983          DOI: 10.1111/j.1526-4637.2011.01091.x

Source DB:  PubMed          Journal:  Pain Med        ISSN: 1526-2375            Impact factor:   3.750


  28 in total

1.  Virtual-reality therapy.

Authors:  Hunter G Hoffman
Journal:  Sci Am       Date:  2004-08       Impact factor: 2.142

2.  The tragedy of needless pain.

Authors:  R Melzack
Journal:  Sci Am       Date:  1990-02       Impact factor: 2.142

3.  Virtual reality as an adjunctive pain control during burn wound care in adolescent patients.

Authors:  H G Hoffman; J N Doctor; D R Patterson; G J Carrougher; T A Furness
Journal:  Pain       Date:  2000-03       Impact factor: 6.961

4.  Virtual reality helmet display quality influences the magnitude of virtual reality analgesia.

Authors:  Hunter G Hoffman; Eric J Seibel; Todd L Richards; Thomas A Furness; David R Patterson; Sam R Sharar
Journal:  J Pain       Date:  2006-11       Impact factor: 5.820

Review 5.  Opioid therapy and immunosuppression: a review.

Authors:  Ricardo Vallejo; Oscar de Leon-Casasola; Ramsun Benyamin
Journal:  Am J Ther       Date:  2004 Sep-Oct       Impact factor: 2.688

6.  Water-friendly virtual reality pain control during wound care.

Authors:  Hunter G Hoffman; David R Patterson; Jeff Magula; Gretchen J Carrougher; Karen Zeltzer; Stephen Dagadakis; Sam R Sharar
Journal:  J Clin Psychol       Date:  2004-02

7.  Virtual reality pain control during burn wound debridement in the hydrotank.

Authors:  Hunter G Hoffman; David R Patterson; Eric Seibel; Maryam Soltani; Laura Jewett-Leahy; Sam R Sharar
Journal:  Clin J Pain       Date:  2008-05       Impact factor: 3.442

8.  Comparison of patient satisfaction and self-reports of pain in adult burn-injured patients.

Authors:  Gretchen J Carrougher; J T Ptacek; Sam R Sharar; Shelley Wiechman; Shari Honari; David R Patterson; David M Heimbach
Journal:  J Burn Care Rehabil       Date:  2003 Jan-Feb

9.  Ketamine and lornoxicam for preventing a fentanyl-induced increase in postoperative morphine requirement.

Authors:  Yu Xuerong; Huang Yuguang; Ju Xia; Wang Hailan
Journal:  Anesth Analg       Date:  2008-12       Impact factor: 5.108

10.  Investigation of the potentiation of the analgesic effects of fentanyl by ketamine in humans: a double-blinded, randomised, placebo controlled, crossover study of experimental pain[ISRCTN83088383].

Authors:  Adam P Tucker; Yong Ik Kim; Raymond Nadeson; Colin S Goodchild
Journal:  BMC Anesthesiol       Date:  2005-04-02       Impact factor: 2.217

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  9 in total

Review 1.  Virtual reality hand therapy: A new tool for nonopioid analgesia for acute procedural pain, hand rehabilitation, and VR embodiment therapy for phantom limb pain.

Authors:  Hunter G Hoffman; David A Boe; Eric Rombokas; Christelle Khadra; Sylvie LeMay; Walter J Meyer; Sam Patterson; Ann Ballesteros; Stephen W Pitt
Journal:  J Hand Ther       Date:  2020-05-30       Impact factor: 1.950

2.  Repeated use of immersive virtual reality therapy to control pain during wound dressing changes in pediatric and adult burn patients.

Authors:  Albertus W Faber; David R Patterson; Marco Bremer
Journal:  J Burn Care Res       Date:  2013 Sep-Oct       Impact factor: 1.845

3.  Virtual Reality Analgesia With Interactive Eye Tracking During Brief Thermal Pain Stimuli: A Randomized Controlled Trial (Crossover Design).

Authors:  Najood A Al-Ghamdi; Walter J Meyer; Barbara Atzori; Wadee Alhalabi; Clayton C Seibel; David Ullman; Hunter G Hoffman
Journal:  Front Hum Neurosci       Date:  2020-01-23       Impact factor: 3.169

Review 4.  Virtual reality, music, and pain: developing the premise for an interdisciplinary approach to pain management.

Authors:  Emily Honzel; Sarah Murthi; Barbara Brawn-Cinani; Giancarlo Colloca; Craig Kier; Amitabh Varshney; Luana Colloca
Journal:  Pain       Date:  2019-09       Impact factor: 7.926

5.  Virtual reality distraction decreases routine intravenous sedation and procedure-related pain during preoperative adductor canal catheter insertion: a retrospective study.

Authors:  Pooja G Pandya; T Edward Kim; Steven K Howard; Erica Stary; Jody C Leng; Oluwatobi O Hunter; Edward R Mariano
Journal:  Korean J Anesthesiol       Date:  2017-03-15

6.  Immersive Virtual Reality as an Adjunctive Non-opioid Analgesic for Pre-dominantly Latin American Children With Large Severe Burn Wounds During Burn Wound Cleaning in the Intensive Care Unit: A Pilot Study.

Authors:  Hunter G Hoffman; Robert A Rodriguez; Miriam Gonzalez; Mary Bernardy; Raquel Peña; Wanda Beck; David R Patterson; Walter J Meyer
Journal:  Front Hum Neurosci       Date:  2019-08-08       Impact factor: 3.169

7.  Interacting with virtual objects via embodied avatar hands reduces pain intensity and diverts attention.

Authors:  Hunter G Hoffman
Journal:  Sci Rep       Date:  2021-05-21       Impact factor: 4.379

8.  Attitudes of patients toward adoption of 3D technology in pain assessment: qualitative perspective.

Authors:  Fotios Spyridonis; Gheorghita Ghinea; Andrew O Frank
Journal:  J Med Internet Res       Date:  2013-04-10       Impact factor: 5.428

9.  Virtual Reality Clinical Research: Promises and Challenges.

Authors:  Bernie Garrett; Tarnia Taverner; Diane Gromala; Gordon Tao; Elliott Cordingley; Crystal Sun
Journal:  JMIR Serious Games       Date:  2018-10-17       Impact factor: 4.143

  9 in total

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