Literature DB >> 214695

Specific effect of zinc ions on DNA polymerase activity of avian myeloblastosis virus.

P R Palan, M L Eidinoff.   

Abstract

The effect of selected cations on DNA synthesis by DNA-polymerase of avian myeloblastosis virus (AMV) was studied. Zinc ions at low concentration (0.2mM) in the assay system enhanced the activity about 2 x fold and at higher concentration (2.0 mM) inhibited the activity completely. In contrast, addition of lithium and potassium salts produced inhibitory effects in this ionic concentration range. Replacement of K+ ion had an inhibitory effect on the activity.

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Year:  1978        PMID： 214695     DOI： 10.1007/bf00240277

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  19 in total

1.  A ZN++ REQUIREMENT FOR SYNTHESIS OF DEOXYRIBONUCLEIC ACID BY RAT LIVER.

Authors:  M FUJIOKA; I LIEBERMAN
Journal:  J Biol Chem       Date:  1964-04       Impact factor: 5.157

2.  Effect of zinc ions on the synthesis of herpes simplex virus DNA in infected BSC-1 cells.

Authors:  J Shlomai; Y Asher; Y J Gordon; U Olshevsky; Y Becker
Journal:  Virology       Date:  1975-07       Impact factor: 3.616

3.  Irreversible inhibition of herpes simplex virus replication in BSC-1 cells by zinc ions.

Authors:  Y J Gordon; Y Asher; Y Becker
Journal:  Antimicrob Agents Chemother       Date:  1975-09       Impact factor: 5.191

4.  Effect of zinc ions on synthesis of herpes simplex virus type 2-induced polypeptides.

Authors:  P Gupta; F Rapp
Journal:  Proc Soc Exp Biol Med       Date:  1976-07

5.  Metal activation of DNA synthesis.

Authors:  M A Sirover; L A Loeb
Journal:  Biochem Biophys Res Commun       Date:  1976-06-07       Impact factor: 3.575

6.  Inhibitors of the RNA and DNA dependent polymerase activities of RNA tumour viruses.

Authors:  C Gurgo; R K Ray; L Thiry; M Green
Journal:  Nat New Biol       Date:  1971-01-27

7.  Streptovaricins inhibit RNA dependent DNA polymerase present in an oncogenic RNA virus.

Authors:  W W Brockman; W A Carter; L H Li; F Reusser; F R Nichol
Journal:  Nature       Date:  1971-03-26       Impact factor: 49.962

8.  Inhibition of RNA-dependent DNA polymerase of Rous sarcoma virus by thiosemicarbazones and several cations.

Authors:  W Levinson; A Faras; B Woodson; J Jackson; J M Bishop
Journal:  Proc Natl Acad Sci U S A       Date:  1973-01       Impact factor: 11.205

9.  Inhibitors of DNA polymerases of murine leukemia viruses: activity of ethidium bromide.

Authors:  S Z Hirschman
Journal:  Science       Date:  1971-07-30       Impact factor: 47.728

10.  Inhibition of the DNA polymerase of Rauscher leukemia virus by single-stranded polyribonucleotides.

Authors:  F W Tuominen; F T Kenney
Journal:  Proc Natl Acad Sci U S A       Date:  1971-09       Impact factor: 11.205
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  3 in total

1.  Mechanism of HIV reverse transcriptase inhibition by zinc: formation of a highly stable enzyme-(primer-template) complex with profoundly diminished catalytic activity.

Authors:  Katherine J Fenstermacher; Jeffrey J DeStefano
Journal:  J Biol Chem       Date:  2011-09-26       Impact factor: 5.157

2.  Alternative divalent cations (Zn²⁺, Co²⁺, and Mn²⁺) are not mutagenic at conditions optimal for HIV-1 reverse transcriptase activity.

Authors:  Vasudevan Achuthan; Jeffrey J DeStefano
Journal:  BMC Biochem       Date:  2015-05-03       Impact factor: 4.059

3.  The Role of Zinc in Antiviral Immunity.

Authors:  Scott A Read; Stephanie Obeid; Chantelle Ahlenstiel; Golo Ahlenstiel
Journal:  Adv Nutr       Date:  2019-07-01       Impact factor: 8.701
  3 in total

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