Literature DB >> 170858

Irreversible inhibition of herpes simplex virus replication in BSC-1 cells by zinc ions.

Y J Gordon, Y Asher, Y Becker.   

Abstract

Zinc sulfate added to the medium of herpes simplex virus-infected BSC-1 cells, at a concentration of 0.1 mM, inhibited the synthesis of infectious virus progeny by 95 to 96%. A concentration of 0.2 mM zinc sulfate inhibited herpes simplex virus synthesis by 99.8% as determined by centrifugation in sucrose gradients and by plaque assay on BSC-1 monolayers. The inhibition of herpes simplex virus replication in BSC-1 cells was found to be irreversible.

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Year:  1975        PMID： 170858      PMCID： PMC429321          DOI： 10.1128/AAC.8.3.377

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  TREATMENT OF HERPETIC KERATITIS.

Authors:  A DEROETTH
Journal:  Am J Ophthalmol       Date:  1963-11       Impact factor: 5.258

2.  Effect of zinc ions on the synthesis of herpes simplex virus DNA in infected BSC-1 cells.

Authors:  J Shlomai; Y Asher; Y J Gordon; U Olshevsky; Y Becker
Journal:  Virology       Date:  1975-07       Impact factor: 3.616

3.  Characterization of the large picornaviral polypeptides produced in the presence of zinc ion.

Authors:  B E Butterworth; B D Korant
Journal:  J Virol       Date:  1974-08       Impact factor: 5.103

4.  Zinc ions inhibit replication of rhinoviruses.

Authors:  B D Korant; J C Kauer; B E Butterworth
Journal:  Nature       Date:  1974-04-12       Impact factor: 49.962

5.  [Ca++, histidine, and Zn++ as factors in the formation of giant cells by herpesivirus hominis].

Authors:  D Falke
Journal:  Z Med Mikrobiol Immunol       Date:  1967

6.  Adsorption, penetration and uncoating of herpes simplex virus.

Authors:  E Hochberg; Y Becker
Journal:  J Gen Virol       Date:  1968-03       Impact factor: 3.891

7.  Reversible inhibition of herpes simplex virus replication by hydroxyurea.

Authors:  H S Rosenkranz; Y Becker
Journal:  Antimicrob Agents Chemother       Date:  1973-03       Impact factor: 5.191
  7 in total
  5 in total

1.  Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides.

Authors:  B D Korant; B E Butterworth
Journal:  J Virol       Date:  1976-04       Impact factor: 5.103

2.  Specific effect of zinc ions on DNA polymerase activity of avian myeloblastosis virus.

Authors:  P R Palan; M L Eidinoff
Journal:  Mol Cell Biochem       Date:  1978-11-01       Impact factor: 3.396

3.  Zinc and genital infections.

Authors:  M S Cornell; L J Hinks; H S Singha; V Walker; F E Willmott
Journal:  Genitourin Med       Date:  1987-08

4.  A combined chemical-physical treatment for herpes simplex lesions in guinea pigs.

Authors:  T A Brawner; J E Senne; M Fahim
Journal:  Arch Dermatol Res       Date:  1979-05-29       Impact factor: 3.017

5.  Zinc Sulfate in Narrow Range as an In Vitro Anti-HSV-1 Assay.

Authors:  Mona Fani; Nastaran Khodadad; Saeedeh Ebrahimi; Rahil Nahidsamiei; Manoocher Makvandi; Ali Teimoori; Hadis Langari
Journal:  Biol Trace Elem Res       Date:  2019-04-26       Impact factor: 3.738
  5 in total

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