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Literature DB >> 21460238

Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae.

Abstract

The control of translation is a critical aspect of gene regulation. It is often inversely related to mRNA degradation and is typically controlled during initiation. The Stm1 protein in Saccharomyces cerevisiae has been shown to interact with ribosomes, affect the interaction of eEF3 with ribosomes, and promote the decapping of a subclass of mRNAs. We demonstrate that in vitro Stm1 inhibits translation after formation of an 80S complex. This suggests that Stm1 modulates translation and mRNA decapping by controlling translation elongation.

Entities: Gene Species

Mesh：

Substances：

Year: 2011 PMID： 21460238 PMCID： PMC3078733 DOI： 10.1261/rna.2677311

Source DB: PubMed Journal: RNA ISSN： 1355-8382 Impact factor: 4.942

31 in total

1. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications.

Authors: C B Brachmann; A Davies; G J Cost; E Caputo; J Li; P Hieter; J D Boeke
Journal: Yeast Date: 1998-01-30 Impact factor: 3.239

2. Evolutionary divergence of an elongation factor 3 from Cryptococcus neoformans.

Authors: G Blakely; J Hekman; K Chakraburtty; P R Williamson
Journal: J Bacteriol Date: 2001-04 Impact factor: 3.490

3. Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme.

Authors: T E LaGrandeur; R Parker
Journal: EMBO J Date: 1998-03-02 Impact factor: 11.598

4. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.

Authors: E A Winzeler; D D Shoemaker; A Astromoff; H Liang; K Anderson; B Andre; R Bangham; R Benito; J D Boeke; H Bussey; A M Chu; C Connelly; K Davis; F Dietrich; S W Dow; M El Bakkoury; F Foury; S H Friend; E Gentalen; G Giaever; J H Hegemann; T Jones; M Laub; H Liao; N Liebundguth; D J Lockhart; A Lucau-Danila; M Lussier; N M'Rabet; P Menard; M Mittmann; C Pai; C Rebischung; J L Revuelta; L Riles; C J Roberts; P Ross-MacDonald; B Scherens; M Snyder; S Sookhai-Mahadeo; R K Storms; S Véronneau; M Voet; G Volckaert; T R Ward; R Wysocki; G S Yen; K Yu; K Zimmermann; P Philippsen; M Johnston; R W Davis
Journal: Science Date: 1999-08-06 Impact factor: 47.728

5. Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae.

Authors: D C Schwartz; R Parker
Journal: Mol Cell Biol Date: 1999-08 Impact factor: 4.272

6. Translation-competent extracts from Saccharomyces cerevisiae: effects of L-A RNA, 5' cap, and 3' poly(A) tail on translational efficiency of mRNAs.

Authors: N Iizuka; P Sarnow
Journal: Methods Date: 1997-04 Impact factor: 3.608

7. Yeast Sm-like proteins function in mRNA decapping and decay.

Authors: S Tharun; W He; A E Mayes; P Lennertz; J D Beggs; R Parker
Journal: Nature Date: 2000-03-30 Impact factor: 49.962

8. One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs.

Authors: Toshifumi Inada; Eric Winstall; Salvador Z Tarun; John R Yates; Dave Schieltz; Alan B Sachs
Journal: RNA Date: 2002-07 Impact factor: 4.942

9. Yeast elongation factor 3: structure and function.

Authors: K Chakraburtty; F J Triana-Alonso
Journal: Biol Chem Date: 1998-07 Impact factor: 3.915

10. Comparative analysis of ribosome-associated adenosinetriphosphatase (ATPase) from pig liver and the ATPase of elongation factor 3 from Saccharomyces cerevisiae.

Authors: O Kovalchuke; K Chakraburtty
Journal: Eur J Biochem Date: 1994-11-15

32 in total

Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae.

1. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications.

2. Evolutionary divergence of an elongation factor 3 from Cryptococcus neoformans.

3. Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme.

4. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.

5. Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae.

6. Translation-competent extracts from Saccharomyces cerevisiae: effects of L-A RNA, 5' cap, and 3' poly(A) tail on translational efficiency of mRNAs.

7. Yeast Sm-like proteins function in mRNA decapping and decay.

8. One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs.

9. Yeast elongation factor 3: structure and function.

10. Comparative analysis of ribosome-associated adenosinetriphosphatase (ATPase) from pig liver and the ATPase of elongation factor 3 from Saccharomyces cerevisiae.

Review 1. One core, two shells: bacterial and eukaryotic ribosomes.

Review 2. P-bodies and stress granules: possible roles in the control of translation and mRNA degradation.

Review 3. Translational control in cellular and developmental processes.

4. Dissecting macromolecular recognition sites in ribosome: implication to its self-assembly.

5. Gle1 Regulates RNA Binding of the DEAD-Box Helicase Ded1 in Its Complex Role in Translation Initiation.

6. Codon optimality and mRNA decay.

7. A naturally thermolabile activity compromises genetic analysis of telomere function in Saccharomyces cerevisiae.

8. Gle1 is a multifunctional DEAD-box protein regulator that modulates Ded1 in translation initiation.

9. Dom34 rescues ribosomes in 3' untranslated regions.

Review 10. The intimate relationships of mRNA decay and translation.