Literature DB >> 21358276

T-body formation precedes virus-like particle maturation in S. cerevisiae.

Francisco Malagon1, Torben Heick Jensen.   

Abstract

T-bodies are localized S. cerevisiae RNPs containing Ty1 retroviral components and speculated to play a role in the assembly of virus-like particles (VLPs). Mapping requirements for T-body formation, we demonstrate that ectopic expression of immature TyA1/Gag (Gag-p49), a structural component of the Ty1 capsid, is sufficient for T-body formation both under normal conditions as well as in a strain background devoid of endogenous Gag. Moreover, T-bodies are readily formed when Ty1 transposition is blocked. Thus, T-bodies represent an early stage in the Ty1 life cycle, preceding VLP maturation.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21358276      PMCID： PMC3127098          DOI： 10.4161/rna.8.2.14822

Source DB:  PubMed          Journal:  RNA Biol        ISSN： 1547-6286            Impact factor:   4.652


  29 in total

1.  Ty element transposition: reverse transcriptase and virus-like particles.

Authors:  D J Garfinkel; J D Boeke; G R Fink
Journal:  Cell       Date:  1985-09       Impact factor: 41.582

2.  The functions and relationships of Ty-VLP proteins in yeast reflect those of mammalian retroviral proteins.

Authors:  S E Adams; J Mellor; K Gull; R B Sim; M F Tuite; S M Kingsman; A J Kingsman
Journal:  Cell       Date:  1987-04-10       Impact factor: 41.582

3.  Differential effects of chromatin and Gcn4 on the 50-fold range of expression among individual yeast Ty1 retrotransposons.

Authors:  Antonin Morillon; Lionel Bénard; Mathias Springer; Pascale Lesage
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

4.  Single-step selection for Ty1 element retrotransposition.

Authors:  M J Curcio; D J Garfinkel
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-01       Impact factor: 11.205

5.  Transpositional competence and transcription of endogenous Ty elements in Saccharomyces cerevisiae: implications for regulation of transposition.

Authors:  M J Curcio; N J Sanders; D J Garfinkel
Journal:  Mol Cell Biol       Date:  1988-09       Impact factor: 4.272

6.  The Saccharomyces cerevisiae genome contains functional and nonfunctional copies of transposon Ty1.

Authors:  J D Boeke; D Eichinger; D Castrillon; G R Fink
Journal:  Mol Cell Biol       Date:  1988-04       Impact factor: 4.272

7.  The gag homologue of retrotransposon Ty1 assembles into spherical particles in Escherichia coli.

Authors:  C Luschnig; M Hess; O Pusch; J Brookman; A Bachmair
Journal:  Eur J Biochem       Date:  1995-03-15

8.  A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

Authors:  R S Sikorski; P Hieter
Journal:  Genetics       Date:  1989-05       Impact factor: 4.562

9.  Ribosomal frameshifting in the yeast retrotransposon Ty: tRNAs induce slippage on a 7 nucleotide minimal site.

Authors:  M F Belcourt; P J Farabaugh
Journal:  Cell       Date:  1990-07-27       Impact factor: 41.582

10.  Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype.

Authors:  E H Kislauskis; X Zhu; R H Singer
Journal:  J Cell Biol       Date:  1994-10       Impact factor: 10.539
View more
  14 in total

1.  Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability.

Authors:  Melissa N Patterson; Alison E Scannapieco; Pak Ho Au; Savanna Dorsey; Catherine A Royer; Patrick H Maxwell
Journal:  DNA Repair (Amst)       Date:  2015-08-07

2.  The Ty1 LTR-retrotransposon of budding yeast, Saccharomyces cerevisiae.

Authors:  M Joan Curcio; Sheila Lutz; Pascale Lesage
Journal:  Microbiol Spectr       Date:  2015-04-01

3.  Ty1 gag enhances the stability and nuclear export of Ty1 mRNA.

Authors:  Mary Ann Checkley; Jessica A Mitchell; Linda D Eizenstat; Stephen J Lockett; David J Garfinkel
Journal:  Traffic       Date:  2012-10-17       Impact factor: 6.215

4.  A purine loop and the primer binding site are critical for the selective encapsidation of mouse mammary tumor virus genomic RNA by Pr77Gag.

Authors:  Akhil Chameettachal; Valérie Vivet-Boudou; Fathima Nuzra Nagoor Pitchai; Vineeta N Pillai; Lizna Mohamed Ali; Anjana Krishnan; Serena Bernacchi; Farah Mustafa; Roland Marquet; Tahir A Rizvi
Journal:  Nucleic Acids Res       Date:  2021-05-07       Impact factor: 16.971

5.  A trans-dominant form of Gag restricts Ty1 retrotransposition and mediates copy number control.

Authors:  Agniva Saha; Jessica A Mitchell; Yuri Nishida; Jonathan E Hildreth; Joshua A Ariberre; Wendy V Gilbert; David J Garfinkel
Journal:  J Virol       Date:  2015-01-21       Impact factor: 5.103

6.  Characterizing the functions of Ty1 Gag and the Gag-derived restriction factor p22/p18.

Authors:  Katarzyna Pachulska-Wieczorek; Leszek Błaszczyk; Julita Gumna; Yuri Nishida; Agniva Saha; Marcin Biesiada; David J Garfinkel; Katarzyna J Purzycka
Journal:  Mob Genet Elements       Date:  2016-03-07

7.  Regulation of age-related macular degeneration-like pathology by complement factor H.

Authors:  Christopher B Toomey; Una Kelly; Daniel R Saban; Catherine Bowes Rickman
Journal:  Proc Natl Acad Sci U S A       Date:  2015-05-19       Impact factor: 11.205

Review 8.  Nuclear trafficking of retroviral RNAs and Gag proteins during late steps of replication.

Authors:  Matthew S Stake; Darrin V Bann; Rebecca J Kaddis; Leslie J Parent
Journal:  Viruses       Date:  2013-11-18       Impact factor: 5.048

9.  Co-translational localization of an LTR-retrotransposon RNA to the endoplasmic reticulum nucleates virus-like particle assembly sites.

Authors:  Jung H Doh; Sheila Lutz; M Joan Curcio
Journal:  PLoS Genet       Date:  2014-03-06       Impact factor: 5.917

10.  The Ty1 Retrotransposon Restriction Factor p22 Targets Gag.

Authors:  Jessica M Tucker; Morgan E Larango; Lucas P Wachsmuth; Natarajan Kannan; David J Garfinkel
Journal:  PLoS Genet       Date:  2015-10-09       Impact factor: 5.917
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.