Literature DB >> 21306567

Synthesis and antiviral evaluation of new N-acylhydrazones containing glycine residue.

Baohe Tian1, Meizi He, Zhiwu Tan, Shixing Tang, Indira Hewlett, Shuguang Chen, Yinxue Jin, Ming Yang.   

Abstract

N-acylhydrazones containing glycine residue 3a-j and 8a-h were synthesized as HIV-1 capsid protein assembly inhibitors. The structures of the novel N-acylhydrazone derivatives were characterized using different spectroscopic methods. Antiviral activity demonstrated that compound 8c bearing 4-methylphenyl moiety was the most active with low cytotoxicity.
© 2011 John Wiley & Sons A/S.

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Year:  2011        PMID： 21306567     DOI： 10.1111/j.1747-0285.2010.01050.x

Source DB:  PubMed          Journal:  Chem Biol Drug Des        ISSN： 1747-0277            Impact factor:   2.817


  9 in total

1.  Crystal structure of (E)-N-{2-[2-(4-methyl-benzyl-idene)hydrazin-1-yl]-2-oxoeth-yl}-p-toluene-sulfonamide.

Authors:  H Purandara; Sabine Foro; B Thimme Gowda
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-05-30

2.  Crystal structure of (E)-N-{2-[2-(3-chloro-benzyl-idene)hydrazin-yl]-2-oxoeth-yl}-4-methyl-benzene-sulfonamide monohydrate.

Authors:  H Purandara; Sabine Foro; B Thimme Gowda
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-05-09

3.  Crystal structures of three ortho-substituted N-acyl-hydrazone derivatives.

Authors:  H Purandara; Sabine Foro; B Thimme Gowda
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2017-11-28

4.  Synthesis and antibacterial evaluation of New N-acylhydrazone derivatives from dehydroabietic acid.

Authors:  Wen Gu; Rongrong Wu; Shilong Qi; Chenhai Gu; Fanjunnan Si; Zhuhui Chen
Journal:  Molecules       Date:  2012-04-20       Impact factor: 4.411

5.  2-{(1E)-[(E)-2-(2,6-Di-chloro-benzyl-idene)hydrazin-1-yl-idene]meth-yl}phenol: crystal structure, Hirshfeld surface analysis and computational study.

Authors:  Rohit B Manawar; Mitesh B Gondaliya; Manish K Shah; Mukesh M Jotani; Edward R T Tiekink
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2019-09-10

6.  Crystal structure, Hirshfeld surface analysis and computational study of bis-(2-{[(2,6-di-chloro-benzyl-idene)hydrazinyl-idene]meth-yl}phenolato)cobalt(II) and of the copper(II) analogue.

Authors:  Rohit B Manawar; Mayank J Mamtora; Manish K Shah; Mukesh M Jotani; Edward R T Tiekink
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2020-01-01

7.  Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor.

Authors:  Micael Rodrigues Cunha; Rajesh Bhardwaj; Aline Lucie Carrel; Sonja Lindinger; Christoph Romanin; Roberto Parise-Filho; Matthias A Hediger; Jean-Louis Reymond
Journal:  RSC Med Chem       Date:  2020-07-16

8.  Synthesis of some new acylhydrazone compounds containing the 1,2,4-triazole structure and their neuritogenic activities in Neuro-2a cells.

Authors:  Xia Jiang; Genyun Tang; Jie Yang; Jiacheng Ding; Hongwei Lin; Xiaoliang Xiang
Journal:  RSC Adv       Date:  2020-05-19       Impact factor: 3.361

9.  Crystal structure of (E)-4-methyl-N-{2-[2-(4-nitro-benzyl-idene)hydrazin-1-yl]-2-oxoeth-yl}benzene-sulfonamide N,N-di-methyl-formamide monosolvate.

Authors:  H Purandara; Sabine Foro; B Thimme Gowda
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2017-10-20
  9 in total

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