| Literature DB >> 21278792 |
Abstract
The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senescence by regulating genes implicated in S-phase progression and mitosis.Entities:
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Year: 2011 PMID: 21278792 DOI: 10.1038/onc.2010.641
Source DB: PubMed Journal: Oncogene ISSN: 0950-9232 Impact factor: 9.867