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Literature DB >> 25142731

Pro-survival role of MITF in melanoma.

Abstract

Melanoma is a therapy-resistant skin cancer due to numerous mechanisms supporting cell survival. Although components of melanoma cytoprotective mechanisms are overexpressed in many types of tumors, some of their regulators are characteristic for melanoma. Several genes mediating pro-survival functions have been identified as direct targets of microphthalmia-associated transcription factor (MITF), a melanocyte-specific modulator also recognized as a lineage addiction oncogene in melanoma. BRAF(V600E) and other proteins deregulated in melanoma influence MITF expression and activity, or they are the partners of MITF in melanoma response to radiotherapy and chemotherapeutics. In this review, the pro-survival activity of MITF is discussed.

Entities: Disease Gene Mutation

Mesh：

Substances：

Year: 2014 PMID： 25142731 DOI： 10.1038/jid.2014.319

Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551

109 in total

Review 1. The molecular machinery regulating apoptosis signal transduction and its implication in human physiology and pathophysiologies.

Authors: C T Hellwig; E Passante; M Rehm
Journal: Curr Mol Med Date: 2011-02 Impact factor: 2.222

2. Regulation of MITF stability by the USP13 deubiquitinase.

Authors: Xiansi Zhao; Brian Fiske; Akinori Kawakami; Juying Li; David E Fisher
Journal: Nat Commun Date: 2011-08-02 Impact factor: 14.919

3. A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.

Authors: Corine Bertolotto; Fabienne Lesueur; Sandy Giuliano; Thomas Strub; Mahaut de Lichy; Karine Bille; Philippe Dessen; Benoit d'Hayer; Hamida Mohamdi; Audrey Remenieras; Eve Maubec; Arnaud de la Fouchardière; Vincent Molinié; Pierre Vabres; Stéphane Dalle; Nicolas Poulalhon; Tanguy Martin-Denavit; Luc Thomas; Pascale Andry-Benzaquen; Nicolas Dupin; Françoise Boitier; Annick Rossi; Jean-Luc Perrot; Bruno Labeille; Caroline Robert; Bernard Escudier; Olivier Caron; Laurence Brugières; Simon Saule; Betty Gardie; Sophie Gad; Stéphane Richard; Jérôme Couturier; Bin Tean Teh; Paola Ghiorzo; Lorenza Pastorino; Susana Puig; Celia Badenas; Hakan Olsson; Christian Ingvar; Etienne Rouleau; Rosette Lidereau; Philippe Bahadoran; Philippe Vielh; Eve Corda; Hélène Blanché; Diana Zelenika; Pilar Galan; François Aubin; Bertrand Bachollet; Céline Becuwe; Pascaline Berthet; Yves Jean Bignon; Valérie Bonadona; Jean-Louis Bonafe; Marie-Noëlle Bonnet-Dupeyron; Fréderic Cambazard; Jacqueline Chevrant-Breton; Isabelle Coupier; Sophie Dalac; Liliane Demange; Michel d'Incan; Catherine Dugast; Laurence Faivre; Lynda Vincent-Fétita; Marion Gauthier-Villars; Brigitte Gilbert; Florent Grange; Jean-Jacques Grob; Philippe Humbert; Nicolas Janin; Pascal Joly; Delphine Kerob; Christine Lasset; Dominique Leroux; Julien Levang; Jean-Marc Limacher; Cristina Livideanu; Michel Longy; Alain Lortholary; Dominique Stoppa-Lyonnet; Sandrine Mansard; Ludovic Mansuy; Karine Marrou; Christine Matéus; Christine Maugard; Nicolas Meyer; Catherine Nogues; Pierre Souteyrand; Laurence Venat-Bouvet; Hélène Zattara; Valérie Chaudru; Gilbert M Lenoir; Mark Lathrop; Irwin Davidson; Marie-Françoise Avril; Florence Demenais; Robert Ballotti; Brigitte Bressac-de Paillerets
Journal: Nature Date: 2011-10-19 Impact factor: 49.962

Review 4. MITF, the Janus transcription factor of melanoma.

Authors: Dana Koludrovic; Irwin Davidson
Journal: Future Oncol Date: 2013-02 Impact factor: 3.404

Review 5. Pro-apoptotic activity of BH3-only proteins and BH3 mimetics: from theory to potential cancer therapy.

Authors: Mariusz L Hartman; Malgorzata Czyz
Journal: Anticancer Agents Med Chem Date: 2012-10-01 Impact factor: 2.505

6. Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway.

Authors: A E Thurber; G Douglas; E C Sturm; S E Zabierowski; D J Smit; S N Ramakrishnan; E Hacker; J H Leonard; M Herlyn; R A Sturm
Journal: Oncogene Date: 2011-02-28 Impact factor: 9.867

7. Mitf regulation of Dia1 controls melanoma proliferation and invasiveness.

Authors: Suzanne Carreira; Jane Goodall; Laurence Denat; Mercedes Rodriguez; Paolo Nuciforo; Keith S Hoek; Alessandro Testori; Lionel Larue; Colin R Goding
Journal: Genes Dev Date: 2006-12-15 Impact factor: 11.361

8. Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching.

Authors: Ossia M Eichhoff; Ashani Weeraratna; Marie C Zipser; Laurence Denat; Daniel S Widmer; Mai Xu; Lydia Kriegl; Thomas Kirchner; Lionel Larue; Reinhard Dummer; Keith S Hoek
Journal: Pigment Cell Melanoma Res Date: 2011-06-09 Impact factor: 4.693

9. Identifying mRNA, microRNA and protein profiles of melanoma exosomes.

Authors: Deyi Xiao; Joanna Ohlendorf; Yinlu Chen; Douglas D Taylor; Shesh N Rai; Sabine Waigel; Wolfgang Zacharias; Hongying Hao; Kelly M McMasters
Journal: PLoS One Date: 2012-10-09 Impact factor: 3.240

10. Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions.

Authors: Caroline N Mills; Sandeep S Joshi; Richard M Niles
Journal: Mol Cancer Date: 2009-11-17 Impact factor: 27.401

44 in total

Review 1. The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology.

Authors: Akinori Kawakami; David E Fisher
Journal: Lab Invest Date: 2017-03-06 Impact factor: 5.662

2. Vemurafenib and trametinib reduce expression of CTGF and IL-8 in ^V600EBRAF melanoma cells.

Authors: Mariusz L Hartman; Michal Rozanski; Marta Osrodek; Izabela Zalesna; Malgorzata Czyz
Journal: Lab Invest Date: 2017-01-09 Impact factor: 5.662

3. MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.

Authors: Anjan K Pradhan; Praveen Bhoopathi; Sarmistha Talukdar; Danielle Scheunemann; Devanand Sarkar; Webster K Cavenee; Swadesh K Das; Luni Emdad; Paul B Fisher
Journal: Proc Natl Acad Sci U S A Date: 2019-03-06 Impact factor: 11.205

4. Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2.

Authors: Hui Zhao; Guosheng Wu; Ji Zhu; Mengyan Sun; Yuchong Wang; Yongjie Fan; Kai Wu; Hongda Bi; Haiying Dai; Chuan Lv; Chunyu Xue
Journal: Oncol Lett Date: 2017-12-12 Impact factor: 2.967

5. Phenotypic diversity of patient-derived melanoma populations in stem cell medium.

Authors: Malgorzata Sztiller-Sikorska; Mariusz L Hartman; Beata Talar; Justyna Jakubowska; Izabela Zalesna; Malgorzata Czyz
Journal: Lab Invest Date: 2015-04-13 Impact factor: 5.662

Review 6. Molecular mechanisms of flavonoids in melanin synthesis and the potential for the prevention and treatment of melanoma.

Authors: Feng Liu-Smith; Frank L Meyskens
Journal: Mol Nutr Food Res Date: 2016-03-21 Impact factor: 5.914

7. The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics.

Authors: William Giblin; Lauren Bringman-Rodenbarger; Angela H Guo; Surinder Kumar; Alexander C Monovich; Ahmed M Mostafa; Mary E Skinner; Michelle Azar; Ahmed Sa Mady; Carolina H Chung; Namrata Kadambi; Keith-Allen Melong; Ho-Joon Lee; Li Zhang; Peter Sajjakulnukit; Sophie Trefely; Erika L Varner; Sowmya Iyer; Min Wang; James S Wilmott; H Peter Soyer; Richard A Sturm; Antonia L Pritchard; Aleodor A Andea; Richard A Scolyer; Mitchell S Stark; David A Scott; Douglas R Fullen; Marcus W Bosenberg; Sriram Chandrasekaran; Zaneta Nikolovska-Coleska; Monique E Verhaegen; Nathaniel W Snyder; Miguel N Rivera; Andrei L Osterman; Costas A Lyssiotis; David B Lombard
Journal: J Clin Invest Date: 2021-06-15 Impact factor: 14.808

8. Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis.

Authors: Charles-Antoine Assenmacher; Sara F Santagostino; Mark A Oyama; Jean-Christophe Marine; Elise Bonvin; Enrico Radaelli
Journal: J Histochem Cytochem Date: 2020-12-07 Impact factor: 2.479

9. Clinical and Molecular Characterization of Microphthalmia-associated Transcription Factor (MITF)-related Renal Cell Carcinoma.

Authors: Martin Lang; Cathy D Vocke; Christopher J Ricketts; Adam R Metwalli; Mark W Ball; Laura S Schmidt; William M Linehan
Journal: Urology Date: 2020-11-24 Impact factor: 2.649

10. Nomogram Incorporating the WNT/β-Catenin Signaling Pathway for Predicting the Survival of Cutaneous Melanoma.

Authors: Yu-Xin Zhou; Xin Wang; De-Quan Pang; Ying-Man Wang; Jing Bai; Fei Tian; Duo Han; Shuwei Shi; Lei Hu
Journal: Int J Gen Med Date: 2021-06-23