Literature DB >> 2118846

The effect of treatment with interferon-gamma on type II collagen-induced arthritis.

H Nakajima1, H Takamori, Y Hiyama, W Tsukada.   

Abstract

We have investigated the effects of recombinant murine interferon-gamma (rIFN-gamma) on type II collagen-induced arthritis (CA) in DBA/l mice. Therapeutic as well as prophylactic treatment with subcutaneous rIFN-gamma, at 10(5) U/mouse six times a week, inhibited the development of CA without any obvious side effects. The accompanying suppression of anti-CII antibody responses may partly explain the inhibition of CA by rIFN-gamma. The possible role of the anti-inflammatory effect of systemic IFN-gamma in the inhibition of CA is discussed.

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Year:  1990        PMID： 2118846      PMCID： PMC1534996          DOI： 10.1111/j.1365-2249.1990.tb05353.x

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  17 in total

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Journal:  Biochemistry       Date:  1972-12-19       Impact factor: 3.162

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Journal:  Arthritis Rheum       Date:  1989-08

5.  Evaluation of the effects of various anti-arthritic drugs on type II collagen-induced mouse arthritis model.

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Journal:  Immunopharmacology       Date:  1985-08

6.  Specificity of anti-type II collagen antibody response in rats.

Authors:  K Kakimoto; T Hirofuji; T Koga
Journal:  Clin Exp Immunol       Date:  1984-07       Impact factor: 4.330

7.  Immunisation against heterologous type II collagen induces arthritis in mice.

Authors:  J S Courtenay; M J Dallman; A D Dayan; A Martin; B Mosedale
Journal:  Nature       Date:  1980-02-14       Impact factor: 49.962

8.  [Interferon in chronic polyarthritis. Positive effect in clinical evaluation].

Authors:  H J Obert; P H Hofschneider
Journal:  Dtsch Med Wochenschr       Date:  1985-11-15       Impact factor: 0.628

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Authors:  J M Stuart; A S Townes; A H Kang
Journal:  Annu Rev Immunol       Date:  1984       Impact factor: 28.527

10.  Serum transfer of collagen-induced arthritis in mice.

Authors:  J M Stuart; F J Dixon
Journal:  J Exp Med       Date:  1983-08-01       Impact factor: 14.307
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  20 in total

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Authors:  I Gjertsson; O H Hultgren; A Tarkowski
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2.  Th17 cells can provide B cell help in autoantibody induced arthritis.

Authors:  Cynthia L Hickman-Brecks; Jennifer L Racz; Debra M Meyer; Timothy P LaBranche; Paul M Allen
Journal:  J Autoimmun       Date:  2010-11-13       Impact factor: 7.094

3.  Immunosuppressive activity of deer antler extracts of Cervus korean TEMMINCK var. mantchuricus Swinhoe, on type II collagen-induced arthritis.

Authors:  Sung-Koo Kang; Kap-Sung Kim; Sung-Il Kim; Kang-Hyun Chung; In-Seon Lee; Cheorl-Ho Kim
Journal:  In Vitro Cell Dev Biol Anim       Date:  2006 Mar-Apr       Impact factor: 2.416

4.  The Th1-Th2 model--what relevance to inflammatory arthritis?

Authors:  P D Kiely
Journal:  Ann Rheum Dis       Date:  1998-06       Impact factor: 19.103

5.  Effects of a highly selective plasma kallikrein inhibitor on collagen-induced arthritis in mice.

Authors:  Y Fujimori; T Nakamura; K Shimizu; T Yamamuro; K Wanaka; S Okamoto; Y Katsuura
Journal:  Agents Actions       Date:  1993-05

6.  Docosahexaenoic acid reduces inflammation and joint destruction in mice with collagen-induced arthritis.

Authors:  Melissa V Olson; Ying-Chun Liu; Bindi Dangi; J Paul Zimmer; Norman Salem; Julie M Nauroth
Journal:  Inflamm Res       Date:  2013-09-06       Impact factor: 4.575

7.  Increased limb involvement in murine collagen-induced arthritis following treatment with anti-interferon-gamma.

Authors:  R O Williams; D G Williams; M Feldmann; R N Maini
Journal:  Clin Exp Immunol       Date:  1993-05       Impact factor: 4.330

8.  Effect of etodolac on type-II collagen-induced arthritis in mice.

Authors:  K Inoue; A Motonaga; H Suzuka; H Yoshifusa; H Fujisawa; T Nishimura; Y Inoue; F Ueda; Y Shibata; K Kimura
Journal:  Agents Actions       Date:  1993-07

9.  The roles of interleukin-18 in collagen-induced arthritis in the BB rat.

Authors:  X J Ye; B Tang; Z Ma; A H Kang; L K Myers; M A Cremer
Journal:  Clin Exp Immunol       Date:  2004-06       Impact factor: 4.330

10.  Cell-mediated transfer of collagen-induced arthritis in mice and its application to the analysis of the inhibitory effects of interferon-gamma and cyclophosphamide.

Authors:  H Nakajima; Y Hiyama; H Takamori; W Tsukada
Journal:  Clin Exp Immunol       Date:  1993-05       Impact factor: 4.330
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