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Literature DB >> 21079648

TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine.

Haikuo Zhang, Xin Zhang, Erin Clark, Michelle Mulcahey, Stephen Huang, Yujiang Geno Shi.

Abstract

Entities: Chemical Gene

Mesh：

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Year: 2010 PMID： 21079648 DOI： 10.1038/cr.2010.156

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

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90 in total

1. Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders.

Authors: Aaron J Towers; Martine W Tremblay; Leeyup Chung; Xin-Lei Li; Alexandra L Bey; Wenhao Zhang; Xinyu Cao; Xiaoming Wang; Ping Wang; Lara J Duffney; Stephen K Siecinski; Sonia Xu; Yuna Kim; Xiangyin Kong; Simon Gregory; Wei Xie; Yong-Hui Jiang
Journal: JCI Insight Date: 2018-12-06

2. Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.

Authors: Yufei Xu; Feizhen Wu; Li Tan; Lingchun Kong; Lijun Xiong; Jie Deng; Andrew J Barbera; Lijuan Zheng; Haikuo Zhang; Stephen Huang; Jinrong Min; Thomas Nicholson; Taiping Chen; Guoliang Xu; Yang Shi; Kun Zhang; Yujiang Geno Shi
Journal: Mol Cell Date: 2011-04-21 Impact factor: 17.970

TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine.

1. Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders.

2. Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.

3. Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate.

4. Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells.

Review 5. TET family proteins: new players in gliomas.

6. Identification of TET1 Partners That Control Its DNA-Demethylating Function.

Review 7. Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond.

Review 8. Vitamin C in Stem Cell Reprogramming and Cancer.

Review 9. 5-Hydroxymethylcytosine--the elusive epigenetic mark in mammalian DNA.

Review 10. Epigenetics: the link between nature and nurture.