Literature DB >> 2104661

Copy choice mechanism of immunoglobulin heavy-chain switch recombination.

W Dunnick1, J Stavnezer.   

Abstract

The immunoglobulin heavy-chain switch is mediated by a recombination event between DNA switch regions associated with donor and recipient constant-region genes. We have determined that the mutations which can be found in some switch regions after recombination appear to arise on only one strand of DNA. This result suggests that switch recombination involves error-prone synthesis of one DNA strand and ligation of the other strand from preexisting DNA.

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Year:  1990        PMID： 2104661      PMCID： PMC360764          DOI： 10.1128/mcb.10.1.397-400.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  25 in total

1.  Products and implied mechanism of H chain switch recombination.

Authors:  J Petrini; W A Dunnick
Journal:  J Immunol       Date:  1989-04-15       Impact factor: 5.422

2.  Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch.

Authors:  W Dunnick; M Wilson; J Stavnezer
Journal:  Mol Cell Biol       Date:  1989-05       Impact factor: 4.272

3.  I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch.

Authors:  D Klein; J Nietupski; S Sirlin; J Stavnezer
Journal:  J Immunol       Date:  1988-03-01       Impact factor: 5.422

4.  Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing.

Authors:  F Sanger; A R Coulson; B G Barrell; A J Smith; B A Roe
Journal:  J Mol Biol       Date:  1980-10-25       Impact factor: 5.469

5.  Expression of 2 immunoglobulin isotypes, IgM and IgA, with identical idiotype in the B cell lymphoma I.29.

Authors:  R Sitia; A Rubartelli; U Hammerling
Journal:  J Immunol       Date:  1981-10       Impact factor: 5.422

6.  DNA sequences mediating class switching in alpha-immunoglobulins.

Authors:  M M Davis; S K Kim; L E Hood
Journal:  Science       Date:  1980-09-19       Impact factor: 47.728

7.  Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes.

Authors:  H Sakano; R Maki; Y Kurosawa; W Roeder; S Tonegawa
Journal:  Nature       Date:  1980-08-14       Impact factor: 49.962

8.  An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing.

Authors:  W Dunnick; T H Rabbitts; C Milstein
Journal:  Nature       Date:  1980-08-14       Impact factor: 49.962

9.  Cell cycle kinetics model of LPS-stimulated spleen cells correlates switch region rearrangements with S phase.

Authors:  A L Kenter; J V Watson
Journal:  J Immunol Methods       Date:  1987-02-26       Impact factor: 2.303

10.  Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes.

Authors:  T Kataoka; T Miyata; T Honjo
Journal:  Cell       Date:  1981-02       Impact factor: 41.582
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  20 in total

Review 1.  Evolutionary consequences of nonrandom damage and repair of chromatin domains.

Authors:  T Boulikas
Journal:  J Mol Evol       Date:  1992-08       Impact factor: 2.395

2.  mRNA transcripts initiating within the human immunoglobulin mu heavy chain enhancer region contain a non-translatable exon and are extremely heterogeneous at the 5' end.

Authors:  G A Neale; G R Kitchingman
Journal:  Nucleic Acids Res       Date:  1991-05-11       Impact factor: 16.971

3.  Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates.

Authors:  J Li; G A Daniels; M R Lieber
Journal:  Nucleic Acids Res       Date:  1996-06-01       Impact factor: 16.971

4.  Analysis of immunoglobulin Sgamma3 recombination breakpoints by PCR: implications for the mechanism of isotype switching.

Authors:  J Du; Y Zhu; A Shanmugam; A L Kenter
Journal:  Nucleic Acids Res       Date:  1997-08-01       Impact factor: 16.971

Review 5.  DNA sequences at immunoglobulin switch region recombination sites.

Authors:  W Dunnick; G Z Hertz; L Scappino; C Gritzmacher
Journal:  Nucleic Acids Res       Date:  1993-02-11       Impact factor: 16.971

6.  RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination.

Authors:  G A Daniels; M R Lieber
Journal:  Nucleic Acids Res       Date:  1995-12-25       Impact factor: 16.971

7.  Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination.

Authors:  Carol E Schrader; Sean P Bradley; Joycelyn Vardo; Sofia N Mochegova; Erin Flanagan; Janet Stavnezer
Journal:  EMBO J       Date:  2003-11-03       Impact factor: 11.598

8.  Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells.

Authors:  S K Shapira; H H Jabara; C P Thienes; D J Ahern; D Vercelli; H J Gould; R S Geha
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205

9.  Internal IgH class switch region deletions are position-independent and enhanced by AID expression.

Authors:  Darryll D Dudley; John P Manis; Ali A Zarrin; Lianne Kaylor; Ming Tian; Frederick W Alt
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-11       Impact factor: 11.205

10.  Mapping of a functional recombination motif that defines isotype specificity for mu-->gamma3 switch recombination implicates NF-kappaB p50 as the isotype-specific switching factor.

Authors:  Amy L Kenter; Robert Wuerffel; Carmen Dominguez; Ananth Shanmugam; Hongmei Zhang
Journal:  J Exp Med       Date:  2004-03-01       Impact factor: 14.307
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